(12 nodes) GroEL-like equatorial domain superfamily network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cct4	T-complex protein 1 subunit delta. (582 aa)
	Bbs12	Bardet-Biedl syndrome 12. (655 aa)
	cct7	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (567 aa)
	mkks	McKusick-Kaufman syndrome. (596 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (535 aa)
	cct8	Chaperonin containing TCP1, subunit 8 (theta). (558 aa)
	bbs10	Uncharacterized protein. (618 aa)
	hspd1	Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family. (574 aa)
	tcp1	T-complex 1. (558 aa)
	cct6a	Chaperonin containing TCP1, subunit 6A (zeta 1). (531 aa)
	cct3	T-complex protein 1 subunit gamma. (541 aa)
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bbs12	Cct4	ENSAMXP00000025563	ENSAMXP00000003135	Bardet-Biedl syndrome 12.	T-complex protein 1 subunit delta.	0.625
Bbs12	bbs10	ENSAMXP00000025563	ENSAMXP00000004228	Bardet-Biedl syndrome 12.	Uncharacterized protein.	0.890
Bbs12	cct2	ENSAMXP00000025563	ENSAMXP00000049423	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1, subunit 2 (beta).	0.625
Bbs12	cct3	ENSAMXP00000025563	ENSAMXP00000019003	Bardet-Biedl syndrome 12.	T-complex protein 1 subunit gamma.	0.625
Bbs12	cct5	ENSAMXP00000025563	ENSAMXP00000021238	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1, subunit 5 (epsilon).	0.625
Bbs12	cct6a	ENSAMXP00000025563	ENSAMXP00000017688	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1, subunit 6A (zeta 1).	0.429
Bbs12	cct8	ENSAMXP00000025563	ENSAMXP00000036009	Bardet-Biedl syndrome 12.	Chaperonin containing TCP1, subunit 8 (theta).	0.666
Bbs12	mkks	ENSAMXP00000025563	ENSAMXP00000050360	Bardet-Biedl syndrome 12.	McKusick-Kaufman syndrome.	0.852
Bbs12	tcp1	ENSAMXP00000025563	ENSAMXP00000011128	Bardet-Biedl syndrome 12.	T-complex 1.	0.779
Cct4	Bbs12	ENSAMXP00000003135	ENSAMXP00000025563	T-complex protein 1 subunit delta.	Bardet-Biedl syndrome 12.	0.625
Cct4	bbs10	ENSAMXP00000003135	ENSAMXP00000004228	T-complex protein 1 subunit delta.	Uncharacterized protein.	0.935
Cct4	cct2	ENSAMXP00000003135	ENSAMXP00000049423	T-complex protein 1 subunit delta.	Chaperonin containing TCP1, subunit 2 (beta).	0.999
Cct4	cct3	ENSAMXP00000003135	ENSAMXP00000019003	T-complex protein 1 subunit delta.	T-complex protein 1 subunit gamma.	0.999
Cct4	cct5	ENSAMXP00000003135	ENSAMXP00000021238	T-complex protein 1 subunit delta.	Chaperonin containing TCP1, subunit 5 (epsilon).	0.999
Cct4	cct6a	ENSAMXP00000003135	ENSAMXP00000017688	T-complex protein 1 subunit delta.	Chaperonin containing TCP1, subunit 6A (zeta 1).	0.999
Cct4	cct7	ENSAMXP00000003135	ENSAMXP00000052637	T-complex protein 1 subunit delta.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
Cct4	cct8	ENSAMXP00000003135	ENSAMXP00000036009	T-complex protein 1 subunit delta.	Chaperonin containing TCP1, subunit 8 (theta).	0.999
Cct4	hspd1	ENSAMXP00000003135	ENSAMXP00000002258	T-complex protein 1 subunit delta.	Heat shock 60 protein 1; Belongs to the chaperonin (HSP60) family.	0.513
Cct4	mkks	ENSAMXP00000003135	ENSAMXP00000050360	T-complex protein 1 subunit delta.	McKusick-Kaufman syndrome.	0.935
Cct4	tcp1	ENSAMXP00000003135	ENSAMXP00000011128	T-complex protein 1 subunit delta.	T-complex 1.	0.999