STRINGSTRING
cbl cbl W5K1Q3_ASTMX W5K1Q3_ASTMX LTBP3 LTBP3 Usp9x Usp9x tgfb1 tgfb1 W5K7I2_ASTMX W5K7I2_ASTMX nedd4l nedd4l ENSAMXP00000053345 ENSAMXP00000053345 LOC103024357 LOC103024357 LOC103024300 LOC103024300 LOC103038757 LOC103038757 tgfb2 tgfb2 LOC103045951 LOC103045951 LOC103042476 LOC103042476 smad7 smad7 sp1 sp1 ENSAMXP00000050414 ENSAMXP00000050414 meis2 meis2 LOC103029032 LOC103029032 W5KB64_ASTMX W5KB64_ASTMX LOC103028284 LOC103028284 LOC103027845 LOC103027845 itgb8 itgb8 irx3 irx3 ccnt2 ccnt2 LOC103030452 LOC103030452 fkbp1b fkbp1b LOC103044361 LOC103044361 FBN1 FBN1 LOC103042889 LOC103042889 LOC103044996 LOC103044996 ENSAMXP00000042051 ENSAMXP00000042051 smurf1 smurf1 UBB UBB ENSAMXP00000040529 ENSAMXP00000040529 trim33 trim33 atp1b4 atp1b4 e2f5 e2f5 kxd1 kxd1 ube2d1 ube2d1 ENSAMXP00000038206 ENSAMXP00000038206 LOC111189978 LOC111189978 LOC103030936 LOC103030936 strap strap rps27a rps27a ldlrad4 ldlrad4 LOC103037767 LOC103037767 smad2 smad2 LOC103040235 LOC103040235 ccnq ccnq f11r f11r Cgn Cgn uba52 uba52 ENSAMXP00000033683 ENSAMXP00000033683 ube2m ube2m W5KF46_ASTMX W5KF46_ASTMX parp1 parp1 men1 men1 snw1 snw1 LOC103032373 LOC103032373 rbl1 rbl1 LOC103027004 LOC103027004 LOC103031474 LOC103031474 LOC103040682 LOC103040682 PARD3 PARD3 LOC103025323 LOC103025323 ENSAMXP00000044583 ENSAMXP00000044583 ENSAMXP00000043951 ENSAMXP00000043951 W5L7A1_ASTMX W5L7A1_ASTMX LOC103043996 LOC103043996 W5L637_ASTMX W5L637_ASTMX W5L563_ASTMX W5L563_ASTMX tgfb3 tgfb3 W5L3X4_ASTMX W5L3X4_ASTMX LOC103046211 LOC103046211 W5L1R3_ASTMX W5L1R3_ASTMX Cdk9 Cdk9 LOC103030012 LOC103030012 LOC103030299 LOC103030299 irx2 irx2 irx1 irx1 W5KYV8_ASTMX W5KYV8_ASTMX SMURF2 SMURF2 Stub1 Stub1 LOC103045580 LOC103045580 Arhgef18 Arhgef18 itga8 itga8 tfdp1 tfdp1 W5LD66_ASTMX W5LD66_ASTMX LOC103043208 LOC103043208 LOC103041389 LOC103041389 LOC103022359 LOC103022359 LOC103029394 LOC103029394 W5LJ85_ASTMX W5LJ85_ASTMX W5LKA6_ASTMX W5LKA6_ASTMX Ncor2 Ncor2 tgfbr2 tgfbr2 pard6a pard6a W5LP11_ASTMX W5LP11_ASTMX W5LQI1_ASTMX W5LQI1_ASTMX CDK8 CDK8 LOC103029721 LOC103029721 ENSAMXP00000028486 ENSAMXP00000028486 Ccnt1 Ccnt1 Ltbp2 Ltbp2 W5KYP8_ASTMX W5KYP8_ASTMX LOC103024607 LOC103024607 LOC103042559 LOC103042559 LOC103036846 LOC103036846 meis1 meis1 LOC103043872 LOC103043872 skil skil LOC103027018 LOC103027018 ccnk ccnk W5KCP4_ASTMX W5KCP4_ASTMX LOC103039420 LOC103039420 itgb5 itgb5 LOC103032663 LOC103032663 LOC103027811 LOC103027811 LOC103038944 LOC103038944 LOC103034175 LOC103034175 mapk1 mapk1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (908 aa)
W5K1Q3_ASTMXIntegrin beta; Belongs to the integrin beta chain family. (746 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1247 aa)
Usp9xUbiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2524 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
W5K7I2_ASTMXMeis homeobox 1 a. (364 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1269 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
LOC103024357Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (810 aa)
LOC103024300Mohawk homeobox a. (348 aa)
LOC103038757E2F transcription factor 4. (150 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
LOC103045951Transcription factor. (407 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
smad7Mothers against decapentaplegic homolog. (390 aa)
sp1Uncharacterized protein. (678 aa)
ENSAMXP00000050414E3 ubiquitin-protein ligase. (752 aa)
meis2Meis homeobox 2a. (504 aa)
LOC103029032Par-3 family cell polarity regulator beta b. (1199 aa)
W5KB64_ASTMXWW domain containing transcription regulator 1. (385 aa)
LOC103028284Cyclin T2b; Belongs to the cyclin family. (608 aa)
LOC103027845SKI-like proto-oncogene b. (715 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (790 aa)
irx3Iroquois homeobox 3b. (361 aa)
ccnt2Cyclin T2a; Belongs to the cyclin family. (704 aa)
LOC103030452Iroquois homeobox 4b. (449 aa)
fkbp1bPeptidylprolyl isomerase. (165 aa)
LOC103044361NEDD8 ubiquitin like modifier, like. (80 aa)
FBN1Fibrillin 1. (2759 aa)
LOC103042889Cbl proto-oncogene C, E3 ubiquitin protein ligase. (583 aa)
LOC103044996Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
ENSAMXP00000042051Integrin beta; Belongs to the integrin beta chain family. (503 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
UBBUbiquitin B. (394 aa)
ENSAMXP00000040529Uncharacterized protein. (373 aa)
trim33Tripartite motif containing 33. (1251 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (349 aa)
e2f5E2F transcription factor 5. (375 aa)
kxd1KxDL motif containing 1. (181 aa)
ube2d1Ubiquitin-conjugating enzyme E2D 1b; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSAMXP00000038206JunB proto-oncogene, AP-1 transcription factor subunit b. (300 aa)
LOC111189978Homeobox domain-containing protein. (411 aa)
LOC103030936BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (265 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
rps27aRibosomal protein S27a. (156 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4a. (311 aa)
LOC103037767TGFB-induced factor homeobox 1. (253 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
LOC103040235Peptidylprolyl isomerase. (108 aa)
ccnqCyclin Q; Belongs to the cyclin family. (252 aa)
f11rF11 receptor, tandem duplicate 1. (301 aa)
CgnSi:dkey-238m4.3. (223 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
ENSAMXP00000033683Integrin, alpha V; Belongs to the integrin alpha chain family. (1028 aa)
ube2mUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
parp1Poly [ADP-ribose] polymerase. (1021 aa)
men1Multiple endocrine neoplasia I. (623 aa)
snw1SNW domain containing 1. (539 aa)
LOC103032373Meis homeobox 2b. (381 aa)
rbl1Retinoblastoma-like 1 (p107). (1053 aa)
LOC103027004Mothers against decapentaplegic homolog. (424 aa)
LOC103031474V-ski avian sarcoma viral oncogene homolog b. (964 aa)
LOC103040682NEDD8 ubiquitin like modifier. (89 aa)
PARD3Par-3 family cell polarity regulator. (1394 aa)
LOC103025323Iroquois homeobox 4a. (466 aa)
ENSAMXP00000044583Iroquois homeobox 5b. (398 aa)
ENSAMXP00000043951Integrin beta. (210 aa)
W5L7A1_ASTMXPar-3 family cell polarity regulator beta a. (1088 aa)
LOC103043996Integrin beta; Belongs to the integrin beta chain family. (796 aa)
W5L637_ASTMXFibrillin 2a. (2750 aa)
W5L563_ASTMXCyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (399 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
W5L3X4_ASTMXCyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (447 aa)
LOC103046211V-ski avian sarcoma viral oncogene homolog a. (790 aa)
W5L1R3_ASTMXUSP domain-containing protein; Belongs to the peptidase C19 family. (2529 aa)
Cdk9Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (457 aa)
LOC103030012Prostate transmembrane protein, androgen induced 1. (270 aa)
LOC103030299Peptidylprolyl isomerase. (108 aa)
irx2Iroquois homeobox 2a. (481 aa)
irx1Iroquois homeobox 1a. (448 aa)
W5KYV8_ASTMXRing finger protein 111. (938 aa)
SMURF2E3 ubiquitin-protein ligase. (761 aa)
Stub1STIP1 homology and U-Box containing protein 1. (290 aa)
LOC103045580Homeobox domain-containing protein. (408 aa)
Arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1172 aa)
itga8Integrin, alpha 8; Belongs to the integrin alpha chain family. (1049 aa)
tfdp1Transcription factor. (405 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103043208Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (836 aa)
LOC103041389Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
W5LJ85_ASTMXZinc finger, FYVE domain containing 9a. (1227 aa)
W5LKA6_ASTMXNuclear receptor corepressor 1. (2396 aa)
Ncor2Nuclear receptor corepressor 2. (2241 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
pard6aPar-6 family cell polarity regulator alpha. (392 aa)
W5LP11_ASTMXUncharacterized protein. (1626 aa)
W5LQI1_ASTMXFibrillin 2b. (2754 aa)
CDK8Cyclin dependent kinase 8. (221 aa)
LOC103029721BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b. (276 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
Ccnt1Cyclin T1; Belongs to the cyclin family. (668 aa)
Ltbp2Uncharacterized protein. (689 aa)
W5KYP8_ASTMXPar-3 family cell polarity regulator alpha, b. (1298 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LOC103036846Iroquois homeobox 7. (315 aa)
meis1Meis homeobox 1 b. (482 aa)
LOC103043872Transcription factor. (418 aa)
skilSKI-like proto-oncogene a. (681 aa)
LOC103027018Mohawk homeobox b. (344 aa)
ccnkCyclin K; Belongs to the cyclin family. (541 aa)
W5KCP4_ASTMXLatent transforming growth factor beta binding protein 1. (1455 aa)
LOC103039420Myeloid ecotropic viral integration site 3. (415 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (804 aa)
LOC103032663Low density lipoprotein receptor class A domain containing 4b. (331 aa)
LOC103027811Mothers against decapentaplegic homolog. (425 aa)
LOC103038944Protein phosphatase 1, regulatory subunit 15B. (471 aa)
LOC103034175Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (20%) [HD]