37 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccnt2	Cyclin T2a; Belongs to the cyclin family. (704 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)
	LOC103024357	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (810 aa)
	LOC103038757	E2F transcription factor 4. (150 aa)
	LOC103045951	Transcription factor. (407 aa)
	smad7	Mothers against decapentaplegic homolog. (390 aa)
	sp1	Uncharacterized protein. (678 aa)
	LOC103028284	Cyclin T2b; Belongs to the cyclin family. (608 aa)
	LOC103043872	Transcription factor. (418 aa)
	LOC103027811	Mothers against decapentaplegic homolog. (425 aa)
	UBB	Ubiquitin B. (394 aa)
	e2f5	E2F transcription factor 5. (375 aa)
	kxd1	KxDL motif containing 1. (181 aa)
	ENSAMXP00000038206	JunB proto-oncogene, AP-1 transcription factor subunit b. (300 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	smad2	Mothers against decapentaplegic homolog. (468 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (252 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC103027004	Mothers against decapentaplegic homolog. (424 aa)
	Ccnt1	Cyclin T1; Belongs to the cyclin family. (668 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	CDK8	Cyclin dependent kinase 8. (221 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	LOC103041389	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
	LOC103043208	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (836 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	tfdp1	Transcription factor. (405 aa)
	W5L563_ASTMX	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (399 aa)
	W5L3X4_ASTMX	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (447 aa)
	Cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (457 aa)
	W5KYV8_ASTMX	Ring finger protein 111. (938 aa)
	rbl1	Retinoblastoma-like 1 (p107). (1053 aa)
	men1	Multiple endocrine neoplasia I. (623 aa)
	ccnk	Cyclin K; Belongs to the cyclin family. (541 aa)
	W5KB64_ASTMX	WW domain containing transcription regulator 1. (385 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK8	Ccnt1	ENSAMXP00000027220	ENSAMXP00000029477	Cyclin dependent kinase 8.	Cyclin T1; Belongs to the cyclin family.	0.561
CDK8	Cdk9	ENSAMXP00000027220	ENSAMXP00000013753	Cyclin dependent kinase 8.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.626
CDK8	LOC103028284	ENSAMXP00000027220	ENSAMXP00000048529	Cyclin dependent kinase 8.	Cyclin T2b; Belongs to the cyclin family.	0.561
CDK8	ccnk	ENSAMXP00000027220	ENSAMXP00000004977	Cyclin dependent kinase 8.	Cyclin K; Belongs to the cyclin family.	0.720
CDK8	ccnq	ENSAMXP00000027220	ENSAMXP00000034684	Cyclin dependent kinase 8.	Cyclin Q; Belongs to the cyclin family.	0.520
CDK8	ccnt2	ENSAMXP00000027220	ENSAMXP00000043514	Cyclin dependent kinase 8.	Cyclin T2a; Belongs to the cyclin family.	0.561
Ccnt1	CDK8	ENSAMXP00000029477	ENSAMXP00000027220	Cyclin T1; Belongs to the cyclin family.	Cyclin dependent kinase 8.	0.561
Ccnt1	Cdk9	ENSAMXP00000029477	ENSAMXP00000013753	Cyclin T1; Belongs to the cyclin family.	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	0.975
Ccnt1	W5L3X4_ASTMX	ENSAMXP00000029477	ENSAMXP00000014536	Cyclin T1; Belongs to the cyclin family.	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily.	0.561
Ccnt1	W5L563_ASTMX	ENSAMXP00000029477	ENSAMXP00000014975	Cyclin T1; Belongs to the cyclin family.	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.	0.561
Ccnt1	ccnk	ENSAMXP00000029477	ENSAMXP00000004977	Cyclin T1; Belongs to the cyclin family.	Cyclin K; Belongs to the cyclin family.	0.673
Ccnt1	sp1	ENSAMXP00000029477	ENSAMXP00000051043	Cyclin T1; Belongs to the cyclin family.	Uncharacterized protein.	0.555
Cdk9	CDK8	ENSAMXP00000013753	ENSAMXP00000027220	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Cyclin dependent kinase 8.	0.626
Cdk9	Ccnt1	ENSAMXP00000013753	ENSAMXP00000029477	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Cyclin T1; Belongs to the cyclin family.	0.975
Cdk9	ENSAMXP00000028486	ENSAMXP00000013753	ENSAMXP00000028486	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.496
Cdk9	ENSAMXP00000053345	ENSAMXP00000013753	ENSAMXP00000053345	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	MH1 domain-containing protein.	0.496
Cdk9	LOC103022359	ENSAMXP00000013753	ENSAMXP00000018891	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.496
Cdk9	LOC103027004	ENSAMXP00000013753	ENSAMXP00000031297	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.427
Cdk9	LOC103027811	ENSAMXP00000013753	ENSAMXP00000046514	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.427
Cdk9	LOC103028284	ENSAMXP00000013753	ENSAMXP00000048529	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.	Cyclin T2b; Belongs to the cyclin family.	0.975