STRINGSTRING
LOC103030051 LOC103030051 pdk4 pdk4 hagh hagh sucla2 sucla2 Pdhb Pdhb glo1 glo1 LOC103029083 LOC103029083 dlat dlat PDK3 PDK3 ENSAMXP00000039683 ENSAMXP00000039683 LOC103043532 LOC103043532 LOC103035067 LOC103035067 LOC103031800 LOC103031800 W5LV29_ASTMX W5LV29_ASTMX LACTB2 LACTB2 pdpr pdpr Mpc1 Mpc1 ENSAMXP00000031129 ENSAMXP00000031129 ENSAMXP00000031615 ENSAMXP00000031615 L2hgdh L2hgdh LOC103047177 LOC103047177 mblac2 mblac2 idh3a idh3a idh3b idh3b pdp1 pdp1 OGDH OGDH pdk1 pdk1 mpc2 mpc2 dld dld LOC103036986 LOC103036986 sdhd sdhd LOC103028647 LOC103028647 Adhfe1 Adhfe1 ogdh ogdh d2hgdh d2hgdh bsg bsg W5LFX4_ASTMX W5LFX4_ASTMX LOC103045952 LOC103045952 pdhx pdhx LOC103030709 LOC103030709 cs cs ACO2 ACO2 dlst dlst Sdhc Sdhc LOC103028316 LOC103028316 LOC103043721 LOC103043721 LOC103046317 LOC103046317 LOC103026358 LOC103026358 LOC103029821 LOC103029821 LOC103046247 LOC103046247 ldhb ldhb Sdha Sdha vdac1 vdac1 sdhb sdhb LOC103046511 LOC103046511 ppard ppard mdh2 mdh2 HAGHL HAGHL LOC103033906 LOC103033906 LOC103026590 LOC103026590 ENSAMXP00000042750 ENSAMXP00000042750 suclg2 suclg2 idh2 idh2 W5KHI0_ASTMX W5KHI0_ASTMX SUCLG1 SUCLG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103030051Malic enzyme. (588 aa)
pdk4Protein-serine/threonine kinase. (419 aa)
haghHydroxyacylglutathione hydrolase. (307 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (466 aa)
PdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (348 aa)
glo1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (180 aa)
LOC103029083Malic enzyme. (615 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (638 aa)
PDK3Protein-serine/threonine kinase. (406 aa)
ENSAMXP00000039683Nicotinamide nucleotide transhydrogenase 2. (954 aa)
LOC103043532Protein-serine/threonine kinase. (405 aa)
LOC103035067Protein-serine/threonine kinase. (408 aa)
LOC103031800Putative pyruvate dehydrogenase phosphatase isoenzyme 2. (530 aa)
W5LV29_ASTMXFumarylacetoacetate hydrolase domain containing 1. (229 aa)
LACTB2Lactamase beta 2. (287 aa)
pdprPyruvate dehydrogenase phosphatase regulatory subunit. (893 aa)
Mpc1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (99 aa)
ENSAMXP00000031129Uncharacterized protein. (199 aa)
ENSAMXP00000031615Malic enzyme. (544 aa)
L2hgdhL-2-hydroxyglutarate dehydrogenase. (417 aa)
LOC103047177L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
mblac2Metallo-beta-lactamase domain containing 2. (274 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (395 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
pdp1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (521 aa)
OGDHOxoglutarate dehydrogenase. (1054 aa)
pdk1Protein-serine/threonine kinase. (407 aa)
mpc2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
LOC103036986PNKD metallo-beta-lactamase domain containing. (361 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
LOC103028647L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
Adhfe1Alcohol dehydrogenase iron containing 1. (437 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (1025 aa)
d2hgdhD-2-hydroxyglutarate dehydrogenase. (520 aa)
bsgBasigin. (394 aa)
W5LFX4_ASTMXIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (306 aa)
LOC103045952Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (390 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (504 aa)
LOC103030709Nicotinamide nucleotide transhydrogenase. (1082 aa)
csCitrate synthase; Belongs to the citrate synthase family. (468 aa)
ACO2Aconitase 2. (686 aa)
dlstDihydrolipoamide S-succinyltransferase. (454 aa)
SdhcSuccinate dehydrogenase complex, subunit C, integral membrane protein. (140 aa)
LOC103028316Si:ch211-114c12.2. (629 aa)
LOC103043721Oxoglutarate dehydrogenase like. (1010 aa)
LOC103046317Protein-serine/threonine kinase. (409 aa)
LOC103026358Peroxisome proliferator-activated receptor delta a. (490 aa)
LOC103029821Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
LOC103046247Retinoid x receptor, alpha b. (501 aa)
ldhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
SdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (626 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
sdhbSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (284 aa)
LOC103046511Zgc:113208. (274 aa)
ppardPeroxisome proliferator-activated receptor delta b. (538 aa)
mdh2Malate dehydrogenase. (338 aa)
HAGHLHydroxyacylglutathione hydrolase like. (277 aa)
LOC103033906Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (143 aa)
LOC103026590Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
ENSAMXP00000042750Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (397 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (429 aa)
idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (469 aa)
W5KHI0_ASTMXRetinoid X receptor, alpha a. (456 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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