STRINGSTRING
psmd7 psmd7 psma3 psma3 psmd1 psmd1 psmd14 psmd14 tgfb1 tgfb1 Psmb6 Psmb6 LOC103034575 LOC103034575 psmd12 psmd12 LOC103022374 LOC103022374 Fndc3b Fndc3b psma5 psma5 ccn2 ccn2 LOC103044365 LOC103044365 LOC103036290 LOC103036290 Rbpjl Rbpjl snw1 snw1 LOC103037200 LOC103037200 psmf1 psmf1 LOC103024607 LOC103024607 fndc3a fndc3a MAML2 MAML2 psmb2 psmb2 LOC103047433 LOC103047433 rbpj rbpj LOC103029567 LOC103029567 hes1 hes1 Zfhx4 Zfhx4 psmd9 psmd9 ep300 ep300 LOC103040644 LOC103040644 psma4 psma4 LOC103024673 LOC103024673 LOC103025308 LOC103025308 Psmd6 Psmd6 LOC103034623 LOC103034623 LOC103026885 LOC103026885 W5L6R5_ASTMX W5L6R5_ASTMX W5L798_ASTMX W5L798_ASTMX psma1 psma1 SMURF2 SMURF2 W5L9B2_ASTMX W5L9B2_ASTMX psma2 psma2 W5LD66_ASTMX W5LD66_ASTMX LOC103022359 LOC103022359 LOC103029394 LOC103029394 cbfb cbfb psmb4 psmb4 Tp53 Tp53 kat2a kat2a psme3 psme3 ccnd1 ccnd1 ENSAMXP00000028486 ENSAMXP00000028486 psmc5 psmc5 ENSAMXP00000029721 ENSAMXP00000029721 psmc2 psmc2 LOC103027004 LOC103027004 LOC103027318 LOC103027318 tead1 tead1 ENSAMXP00000032387 ENSAMXP00000032387 hes4 hes4 LOC103041531 LOC103041531 uba52 uba52 psmd8 psmd8 LOC103037427 LOC103037427 LOC103040093 LOC103040093 LOC103047553 LOC103047553 maml1 maml1 psmb5 psmb5 rps27a rps27a ENSAMXP00000037082 ENSAMXP00000037082 Psme1 Psme1 Psmb7 Psmb7 LOC103024231 LOC103024231 ENSAMXP00000039454 ENSAMXP00000039454 LOC103036097 LOC103036097 UBB UBB zfhx3 zfhx3 smurf1 smurf1 psmc4 psmc4 LOC103039316 LOC103039316 psmd10 psmd10 Crebbp Crebbp LOC103045150 LOC103045150 LOC103033229 LOC103033229 tead3 tead3 lef1 lef1 psmd5 psmd5 psmb1 psmb1 tcf7l2 tcf7l2 Psmd2 Psmd2 LOC103027811 LOC103027811 psmd3 psmd3 psmc6 psmc6 SRC SRC psmb3 psmb3 ENSAMXP00000048293 ENSAMXP00000048293 Mdm2 Mdm2 psmd4 psmd4 psma6 psma6 ENSAMXP00000050414 ENSAMXP00000050414 ctnnb1 ctnnb1 LOC103038924 LOC103038924 LOC103034426 LOC103034426 ENSAMXP00000051608 ENSAMXP00000051608 LOC103025197 LOC103025197 psmc3 psmc3 mamld1 mamld1 ENSAMXP00000053288 ENSAMXP00000053288 ENSAMXP00000053345 ENSAMXP00000053345 psme2 psme2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psmd7Proteasome 26S subunit, non-ATPase 7. (330 aa)
psma3Proteasome subunit alpha type. (255 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (965 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Psmb6Proteasome subunit beta. (248 aa)
LOC103034575Catenin, beta 2. (779 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (481 aa)
LOC103022374Transcription factor 7 like 1b. (583 aa)
Fndc3bFibronectin type III domain containing 3Ba. (1177 aa)
psma5Proteasome subunit alpha type. (241 aa)
ccn2Cellular communication network factor 2a. (362 aa)
LOC103044365E1A binding protein p300 a. (2671 aa)
LOC103036290Proteasome 26S subunit, ATPase 1a; Belongs to the AAA ATPase family. (440 aa)
RbpjlRecombination signal binding protein for immunoglobulin kappa J region-like. (465 aa)
snw1SNW domain containing 1. (539 aa)
LOC103037200Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (460 aa)
psmf1Proteasome inhibitor subunit 1. (269 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
fndc3aFibronectin type III domain containing 3A. (1258 aa)
MAML2Mastermind like transcriptional coactivator 2. (870 aa)
psmb2Proteasome subunit beta. (198 aa)
LOC103047433Proteasome 26S subunit, non-ATPase 11b. (422 aa)
rbpjRecombination signal binding protein for immunoglobulin kappa J region b. (494 aa)
LOC103029567Recombination signal binding protein for immunoglobulin kappa J region a. (502 aa)
hes1Hairy-related 6. (270 aa)
Zfhx4Zinc finger homeobox 4. (3508 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (213 aa)
ep300E1A binding protein p300 b. (2652 aa)
LOC103040644Uncharacterized protein. (1194 aa)
psma4Proteasome subunit alpha type. (261 aa)
LOC103024673Proteasome subunit beta. (216 aa)
LOC103025308Proteasome subunit beta. (272 aa)
Psmd6Proteasome 26S subunit, non-ATPase 6. (358 aa)
LOC103034623Notch receptor 1a. (2450 aa)
LOC103026885Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (796 aa)
W5L6R5_ASTMXTEA domain-containing protein. (423 aa)
W5L798_ASTMXYes-associated protein 1. (431 aa)
psma1Proteasome subunit alpha type. (262 aa)
SMURF2E3 ubiquitin-protein ligase. (761 aa)
W5L9B2_ASTMXTranscription factor 7. (442 aa)
psma2Proteasome subunit alpha type. (234 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
cbfbCore-binding factor subunit beta. (187 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (258 aa)
Tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (356 aa)
kat2aK(lysine) acetyltransferase 2A. (855 aa)
psme3Proteasome activator subunit 3. (264 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
ENSAMXP00000028486Mothers against decapentaplegic homolog. (493 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ENSAMXP00000029721Mastermind-like transcriptional coactivator 3. (1154 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
LOC103027004Mothers against decapentaplegic homolog. (424 aa)
LOC103027318Hairy-related 8.2. (202 aa)
tead1TEA domain family member 1b. (440 aa)
ENSAMXP00000032387BHLH domain-containing protein. (246 aa)
hes4Hairy-related 9. (295 aa)
LOC103041531Runt-related transcription factor. (449 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (267 aa)
LOC103037427Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (394 aa)
LOC103040093Proteasome 26S subunit, non-ATPase 13. (384 aa)
LOC103047553Proteasome 26S subunit, non-ATPase 11a. (421 aa)
maml1Mastermind-like transcriptional coactivator 1. (1070 aa)
psmb5Proteasome subunit beta. (269 aa)
rps27aRibosomal protein S27a. (156 aa)
ENSAMXP00000037082RPN6_C_helix domain-containing protein. (287 aa)
Psme1Proteasome activator subunit 1. (90 aa)
Psmb7Proteasome subunit beta. (273 aa)
LOC103024231TEA domain family member 1a. (424 aa)
ENSAMXP00000039454Proteasome endopeptidase complex. (240 aa)
LOC103036097Ninjurin 2. (130 aa)
UBBUbiquitin B. (394 aa)
zfhx3Zinc finger homeobox 3. (3870 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (420 aa)
LOC103039316Proteasome subunit alpha type. (246 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (240 aa)
CrebbpCREB binding protein a. (2140 aa)
LOC103045150PCI domain-containing protein. (378 aa)
LOC103033229Proteasome subunit alpha type. (246 aa)
tead3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (411 aa)
lef1Lymphoid enhancer-binding factor 1. (384 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
psmb1Proteasome subunit beta. (240 aa)
tcf7l2Transcription factor 7 like 2. (630 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (894 aa)
LOC103027811Mothers against decapentaplegic homolog. (425 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (508 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
SRCTyrosine-protein kinase. (617 aa)
psmb3Proteasome subunit beta. (205 aa)
ENSAMXP00000048293Uncharacterized protein. (3355 aa)
Mdm2MDM2 proto-oncogene. (543 aa)
psmd4Proteasome 26S subunit, non-ATPase 4a. (373 aa)
psma6Proteasome subunit alpha type. (246 aa)
ENSAMXP00000050414E3 ubiquitin-protein ligase. (752 aa)
ctnnb1Catenin (cadherin-associated protein), beta 1. (790 aa)
LOC103038924Tyrosine-protein kinase. (551 aa)
LOC103034426Proteasome subunit beta. (278 aa)
ENSAMXP00000051608Tyrosine-protein kinase. (546 aa)
LOC103025197Notch receptor 1b. (2477 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (385 aa)
mamld1Uncharacterized protein. (994 aa)
ENSAMXP00000053288Proteasome subunit beta. (226 aa)
ENSAMXP00000053345MH1 domain-containing protein. (187 aa)
psme2Proteasome activator subunit 2. (238 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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