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W5K6B4_ASTMX W5K6B4_ASTMX W5K6L6_ASTMX W5K6L6_ASTMX creb1 creb1 LOC103030485 LOC103030485 ENSAMXP00000052466 ENSAMXP00000052466 ENSAMXP00000051733 ENSAMXP00000051733 ENSAMXP00000051608 ENSAMXP00000051608 LOC103040103 LOC103040103 ENSAMXP00000051182 ENSAMXP00000051182 LOC103038924 LOC103038924 ENSAMXP00000050613 ENSAMXP00000050613 uhmk1 uhmk1 LOC103025140 LOC103025140 LOC103038496 LOC103038496 ENSAMXP00000049282 ENSAMXP00000049282 Egf Egf ENSAMXP00000048538 ENSAMXP00000048538 LOC103042520 LOC103042520 LOC103029863 LOC103029863 LOC103028984 LOC103028984 nras nras pik3ca pik3ca SRC SRC ENSAMXP00000046768 ENSAMXP00000046768 ENSAMXP00000046240 ENSAMXP00000046240 LOC103024858-2 LOC103024858-2 gng8 gng8 LOC103024575 LOC103024575 ENSAMXP00000044861 ENSAMXP00000044861 hras hras ENSAMXP00000044322 ENSAMXP00000044322 LOC103033547 LOC103033547 LOC103044996 LOC103044996 akt1 akt1 ENSAMXP00000041454 ENSAMXP00000041454 prmt1 prmt1 LOC103024064 LOC103024064 LOC103021960 LOC103021960 LOC103023460 LOC103023460 gngt2 gngt2 LOC103023031 LOC103023031 LOC103023645 LOC103023645 LOC103031762 LOC103031762 ENSAMXP00000036546 ENSAMXP00000036546 cav2 cav2 LOC103029911 LOC103029911 LOC103034321 LOC103034321 ENSAMXP00000033848 ENSAMXP00000033848 foxo3 foxo3 HSPB1 HSPB1 cdkn1b cdkn1b LOC103035767 LOC103035767 ENSAMXP00000031423 ENSAMXP00000031423 LOC103030920 LOC103030920 gnb1 gnb1 LOC103040197 LOC103040197 gnao1 gnao1 LOC103028370 LOC103028370 LOC111193748 LOC111193748 ENSAMXP00000027821 ENSAMXP00000027821 LOC103024012 LOC103024012 LOC103035761 LOC103035761 LOC103037538 LOC103037538 LOC103027635 LOC103027635 LOC103029182 LOC103029182 akt2 akt2 LOC103045439 LOC103045439 W5LPS7_ASTMX W5LPS7_ASTMX LOC103024139 LOC103024139 LOC103032909 LOC103032909 LOC103024775 LOC103024775 LOC103024858 LOC103024858 LOC103037883 LOC103037883 LOC103043623 LOC103043623 elk1 elk1 LOC103038241 LOC103038241 LOC103032917 LOC103032917 LOC107196998 LOC107196998 gng3 gng3 LOC103030165 LOC103030165 W5LAG0_ASTMX W5LAG0_ASTMX SPHK1 SPHK1 cav3 cav3 LOC103021592 LOC103021592 W5KYT5_ASTMX W5KYT5_ASTMX LOC103031617 LOC103031617 pik3r1 pik3r1 AKT1 AKT1 W5KLY7_ASTMX W5KLY7_ASTMX strn3 strn3 strn4 strn4 W5KJ96_ASTMX W5KJ96_ASTMX zdhhc21 zdhhc21 LOC103033963 LOC103033963 LOC103044429 LOC103044429 LOC103029205 LOC103029205 LOC103035574 LOC103035574 LOC103043741 LOC103043741 LOC103029328 LOC103029328 GNG4 GNG4 zdhhc7 zdhhc7 LOC103023536 LOC103023536 mapk1 mapk1 LOC103042898 LOC103042898 LOC103022926 LOC103022926
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5K6B4_ASTMXExportin 1 (CRM1 homolog, yeast) a. (943 aa)
W5K6L6_ASTMXNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
creb1cAMP responsive element binding protein 1b. (334 aa)
LOC103030485Cyclin-dependent kinase inhibitor 1Ba. (204 aa)
ENSAMXP00000052466Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2. (156 aa)
ENSAMXP00000051733Uncharacterized protein. (227 aa)
ENSAMXP00000051608Tyrosine-protein kinase. (546 aa)
LOC103040103HRas proto-oncogene, GTPase b. (189 aa)
ENSAMXP00000051182ZP domain-containing protein. (372 aa)
LOC103038924Tyrosine-protein kinase. (551 aa)
ENSAMXP00000050613Uncharacterized protein. (85 aa)
uhmk1U2AF homology motif (UHM) kinase 1. (444 aa)
LOC103025140Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC103038496Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (172 aa)
ENSAMXP00000049282DAGKc domain-containing protein. (545 aa)
EgfUncharacterized protein. (284 aa)
ENSAMXP00000048538Uncharacterized protein. (467 aa)
LOC103042520Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (259 aa)
LOC103029863Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (204 aa)
LOC103028984Estrogen receptor 2a. (579 aa)
nrasNRAS proto-oncogene, GTPase. (188 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
SRCTyrosine-protein kinase. (617 aa)
ENSAMXP00000046768Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (78 aa)
ENSAMXP00000046240Uncharacterized protein. (54 aa)
LOC103024858-2Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5. (68 aa)
gng8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC103024575Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSAMXP00000044861Uncharacterized protein. (702 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSAMXP00000044322Uncharacterized protein. (353 aa)
LOC1030335473-phosphoinositide dependent protein kinase 1b. (537 aa)
LOC103044996Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
ENSAMXP00000041454Uncharacterized protein. (89 aa)
prmt1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (362 aa)
LOC103024064Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (286 aa)
LOC103021960BZIP domain-containing protein. (110 aa)
LOC103023460Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
LOC103023031Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
LOC103023645Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC103031762Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
ENSAMXP00000036546SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (584 aa)
cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (164 aa)
LOC103029911Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (340 aa)
LOC103034321Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
ENSAMXP00000033848ZP domain-containing protein. (395 aa)
foxo3Forkhead box O3b. (651 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (182 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (171 aa)
LOC103035767Uncharacterized protein. (314 aa)
ENSAMXP00000031423Guanine nucleotide binding protein (G protein), beta 5b. (367 aa)
LOC103030920Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
gnb1Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
LOC103040197Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
gnao1Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a. (354 aa)
LOC103028370Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
LOC111193748Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (374 aa)
ENSAMXP00000027821Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (77 aa)
LOC103024012Uncharacterized protein. (319 aa)
LOC103035761Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a. (354 aa)
LOC103037538Tyrosine-protein kinase receptor. (1389 aa)
LOC103027635Sphingosine-1-phosphate receptor 3a; Belongs to the G-protein coupled receptor 1 family. (401 aa)
LOC103029182WD_REPEATS_REGION domain-containing protein. (778 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC103045439Tyrosine-protein kinase receptor. (1396 aa)
W5LPS7_ASTMXStriatin, calmodulin binding protein. (764 aa)
LOC103024139Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (731 aa)
LOC103032909Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC103024775Protein arginine methyltransferase 8b; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (413 aa)
LOC103024858Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC103037883Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC103043623Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (173 aa)
elk1ETS transcription factor ELK1. (528 aa)
LOC103038241V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC103032917Guanine nucleotide binding protein (G protein), beta 5a. (353 aa)
LOC107196998Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (76 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC103030165WD_REPEATS_REGION domain-containing protein. (340 aa)
W5LAG0_ASTMXSHC (Src homology 2 domain containing) transforming protein 1. (449 aa)
SPHK1Sphingosine kinase 1. (541 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
LOC103021592Exportin 1 (CRM1 homolog, yeast) b. (1071 aa)
W5KYT5_ASTMXcAMP responsive element modulator a. (252 aa)
LOC103031617Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
W5KLY7_ASTMXEstrogen receptor 2b. (542 aa)
strn3Striatin, calmodulin binding protein 3. (716 aa)
strn4Striatin, calmodulin binding protein 4. (708 aa)
W5KJ96_ASTMXCold shock domain containing E1, RNA-binding. (767 aa)
zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (264 aa)
LOC103033963Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
LOC103044429Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC103029205Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
LOC103035574Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC103043741Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (588 aa)
LOC103029328Guanine nucleotide binding protein (G protein) alpha v1. (379 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
zdhhc7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (300 aa)
LOC103023536Zgc:55558. (187 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
LOC103042898Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (340 aa)
LOC1030229263-phosphoinositide dependent protein kinase 1a. (539 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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