54 items (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccng2	Cyclin G2; Belongs to the cyclin family. (333 aa)
	Bcl6b	BCL6B transcription repressor. (541 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	LOC103022611	Forkhead box O4. (631 aa)
	LOC103044365	E1A binding protein p300 a. (2671 aa)
	sirt3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (353 aa)
	bcl6	BCL6A transcription repressor a. (712 aa)
	Sirt1	Deacetylase sirtuin-type domain-containing protein. (802 aa)
	W5K6L6_ASTMX	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
	btg1	B-cell translocation gene 1, anti-proliferative. (172 aa)
	LOC103045356	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like; Belongs to the 14-3-3 family. (245 aa)
	ENSAMXP00000053345	MH1 domain-containing protein. (187 aa)
	LOC103023259	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa)
	LOC103023504	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (244 aa)
	Nfya	Nuclear transcription factor Y, alpha, like. (280 aa)
	foxo1	Forkhead box O1 a. (661 aa)
	LOC103027811	Mothers against decapentaplegic homolog. (425 aa)
	LOC103047890	Agouti related neuropeptide. (143 aa)
	LOC103024575	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSAMXP00000044206	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (416 aa)
	Crebbp	CREB binding protein a. (2140 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	gdf11	Growth differentiation factor 11. (409 aa)
	LOC103041195	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa)
	LOC103025287	Myostatin a. (348 aa)
	ddit3	DNA-damage-inducible transcript 3. (280 aa)
	smad2	Mothers against decapentaplegic homolog. (468 aa)
	LOC103024851	Forkhead box O6 a. (664 aa)
	LOC103046520	Forkhead box O1 b. (638 aa)
	LOC103026113	Forkhead box O3A. (646 aa)
	foxo3	Forkhead box O3b. (651 aa)
	nfyc	Nuclear transcription factor Y, gamma. (359 aa)
	LOC103027004	Mothers against decapentaplegic homolog. (424 aa)
	ENSAMXP00000031283	Fork-head domain-containing protein. (312 aa)
	ENSAMXP00000031040	Forkhead box O6 b. (678 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (877 aa)
	ENSAMXP00000030615	BTB domain-containing protein. (442 aa)
	ywhaq	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a; Belongs to the 14-3-3 family. (245 aa)
	ENSAMXP00000029520	Fork-head domain-containing protein. (286 aa)
	LOC103043868	Ataxin 3. (341 aa)
	LOC103021402	3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa)
	ENSAMXP00000028486	Mothers against decapentaplegic homolog. (493 aa)
	LOC107197738	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (245 aa)
	W5LU00_ASTMX	Forkhead box G1a. (337 aa)
	W5LTK0_ASTMX	Forkhead box G1b. (323 aa)
	akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC103029394	Mothers against decapentaplegic homolog. (544 aa)
	mstn	Myostatin b. (435 aa)
	LOC103022359	Mothers against decapentaplegic homolog. (587 aa)
	nfyb	Nuclear transcription factor Y, beta a. (204 aa)
	W5LD66_ASTMX	Mothers against decapentaplegic homolog. (573 aa)
	ywhab	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a; Belongs to the 14-3-3 family. (253 aa)
	LOC103026885	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (796 aa)
	ep300	E1A binding protein p300 b. (2652 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	LOC103022611	ENSAMXP00000009486	ENSAMXP00000008548	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O4.	0.907
AKT1	LOC103024851	ENSAMXP00000009486	ENSAMXP00000034873	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O6 a.	0.767
AKT1	LOC103026113	ENSAMXP00000009486	ENSAMXP00000034226	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3A.	0.973
AKT1	LOC103046520	ENSAMXP00000009486	ENSAMXP00000034763	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O1 b.	0.973
AKT1	Sirt1	ENSAMXP00000009486	ENSAMXP00000003809	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Deacetylase sirtuin-type domain-containing protein.	0.407
AKT1	foxo1	ENSAMXP00000009486	ENSAMXP00000047550	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O1 a.	0.973
AKT1	foxo3	ENSAMXP00000009486	ENSAMXP00000032755	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3b.	0.973
Crebbp	ENSAMXP00000028486	ENSAMXP00000043375	ENSAMXP00000028486	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.554
Crebbp	ENSAMXP00000029520	ENSAMXP00000043375	ENSAMXP00000029520	CREB binding protein a.	Fork-head domain-containing protein.	0.431
Crebbp	ENSAMXP00000031040	ENSAMXP00000043375	ENSAMXP00000031040	CREB binding protein a.	Forkhead box O6 b.	0.410
Crebbp	ENSAMXP00000031283	ENSAMXP00000043375	ENSAMXP00000031283	CREB binding protein a.	Fork-head domain-containing protein.	0.431
Crebbp	ENSAMXP00000053345	ENSAMXP00000043375	ENSAMXP00000053345	CREB binding protein a.	MH1 domain-containing protein.	0.554
Crebbp	LOC103022359	ENSAMXP00000043375	ENSAMXP00000018891	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.554
Crebbp	LOC103022611	ENSAMXP00000043375	ENSAMXP00000008548	CREB binding protein a.	Forkhead box O4.	0.811
Crebbp	LOC103024851	ENSAMXP00000043375	ENSAMXP00000034873	CREB binding protein a.	Forkhead box O6 a.	0.410
Crebbp	LOC103026113	ENSAMXP00000043375	ENSAMXP00000034226	CREB binding protein a.	Forkhead box O3A.	0.811
Crebbp	LOC103026885	ENSAMXP00000043375	ENSAMXP00000015457	CREB binding protein a.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.985
Crebbp	LOC103027004	ENSAMXP00000043375	ENSAMXP00000031297	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.703
Crebbp	LOC103027811	ENSAMXP00000043375	ENSAMXP00000046514	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.703
Crebbp	LOC103029394	ENSAMXP00000043375	ENSAMXP00000019787	CREB binding protein a.	Mothers against decapentaplegic homolog.	0.554