STRINGSTRING
tgfb1 tgfb1 W5K668_ASTMX W5K668_ASTMX ago2 ago2 tgfb2 tgfb2 LOC103042476 LOC103042476 LOC111195965 LOC111195965 ENSAMXP00000047619 ENSAMXP00000047619 LOC103032492 LOC103032492 LOC103031629 LOC103031629 ENSAMXP00000043438 ENSAMXP00000043438 Mvp Mvp LOC103039990 LOC103039990 tgfb3 tgfb3 LOC103024607 LOC103024607 drosha drosha
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
W5K668_ASTMXUncharacterized protein. (82 aa)
ago2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (872 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LOC111195965TIR domain-containing protein. (848 aa)
ENSAMXP00000047619CD40 molecule, TNF receptor superfamily member 5. (353 aa)
LOC103032492Receptor protein-tyrosine kinase. (1173 aa)
LOC103031629Receptor protein-tyrosine kinase. (1211 aa)
ENSAMXP00000043438TIR domain-containing protein. (689 aa)
MvpMajor vault protein. (872 aa)
LOC103039990TIR domain-containing protein. (783 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
droshaDrosha ribonuclease III. (1309 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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