STRINGSTRING
W5KHX3_ASTMX W5KHX3_ASTMX LOC103029205 LOC103029205 LOC103031445 LOC103031445 Pdgfra Pdgfra tgfb1 tgfb1 ADAM12 ADAM12 fgb fgb W5L8H6_ASTMX W5L8H6_ASTMX ccn4 ccn4 smad2 smad2 cav2 cav2 LOC103023460 LOC103023460 has3 has3 ENSAMXP00000039153 ENSAMXP00000039153 LOC103045523 LOC103045523 FBN1 FBN1 LOC103035536 LOC103035536 LOC103042476 LOC103042476 tgfb2 tgfb2 Agrn Agrn LOC103031663 LOC103031663 HAPLN1 HAPLN1 LOC103028370 LOC103028370 Lrrc10 Lrrc10 Col1a2 Col1a2 has2 has2 LOC103043623 LOC103043623 fbln1 fbln1 has1 has1 itga8 itga8 W5L7B9_ASTMX W5L7B9_ASTMX cav3 cav3 tgfb3 tgfb3 Adam12 Adam12 LOC103024607 LOC103024607 gpc3 gpc3 W5KK24_ASTMX W5KK24_ASTMX cryab cryab ccn2 ccn2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5KHX3_ASTMXProcollagen, type V, alpha 1. (1408 aa)
LOC103029205Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
LOC103031445Thrombospondin 1b. (1178 aa)
PdgfraPlatelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
ADAM12ADAM metallopeptidase domain 12. (735 aa)
fgbFibrinogen beta chain. (486 aa)
W5L8H6_ASTMXCartilage intermediate layer protein 2. (1213 aa)
ccn4Cellular communication network factor 4b. (358 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (164 aa)
LOC103023460Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
has3Hyaluronan synthase 3. (553 aa)
ENSAMXP00000039153Matrix metallopeptidase 9. (629 aa)
LOC103045523SRY-box transcription factor 9a. (492 aa)
FBN1Fibrillin 1. (2759 aa)
LOC103035536Periostin, osteoblast specific factor a. (947 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
AgrnAgrin. (1998 aa)
LOC103031663Transcription factor 21. (182 aa)
HAPLN1Hyaluronan and proteoglycan link protein 1. (327 aa)
LOC103028370Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
Lrrc10Leucine rich repeat containing 10. (282 aa)
Col1a2Collagen, type I, alpha 2. (1355 aa)
has2Hyaluronan synthase 2. (561 aa)
LOC103043623Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (173 aa)
fbln1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (681 aa)
has1Hyaluronan synthase 1. (566 aa)
itga8Integrin, alpha 8; Belongs to the integrin alpha chain family. (1049 aa)
W5L7B9_ASTMXFibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (665 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
Adam12ADAM metallopeptidase domain 12. (950 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
gpc3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (590 aa)
W5KK24_ASTMXMatrix metallopeptidase 9. (683 aa)
cryabCrystallin, alpha B, b; Belongs to the small heat shock protein (HSP20) family. (172 aa)
ccn2Cellular communication network factor 2a. (362 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (16%) [HD]