STRINGSTRING
axin2 axin2 LOC103023202 LOC103023202 tgfb2 tgfb2 mycn mycn LOC103042476 LOC103042476 ENSAMXP00000051577 ENSAMXP00000051577 myog myog LOC103021971 LOC103021971 Fgfr3 Fgfr3 LOC103025657 LOC103025657 ENSAMXP00000048061 ENSAMXP00000048061 ENSAMXP00000047900 ENSAMXP00000047900 TYR TYR LOC103032492 LOC103032492 plek plek dlx3 dlx3 bmp4 bmp4 LOC103031629 LOC103031629 dlx6 dlx6 dlx5 dlx5 itgb1 itgb1 ENSAMXP00000044581 ENSAMXP00000044581 asip asip LOC103040080 LOC103040080 tia1 tia1 dot1l dot1l wnt16 wnt16 prkd2 prkd2 nfatc1 nfatc1 ENSAMXP00000040318 ENSAMXP00000040318 Slc24a5 Slc24a5 LOC103040843 LOC103040843 slc20a2 slc20a2 ENSAMXP00000038632 ENSAMXP00000038632 ENSAMXP00000038500 ENSAMXP00000038500 fgf2 fgf2 LOC103027532 LOC103027532 atp6v0a1 atp6v0a1 LOC103029324 LOC103029324 prkd1 prkd1 efnb1 efnb1 atf4 atf4 smad2 smad2 LOC103034468 LOC103034468 LOC103024286 LOC103024286 fosb fosb ENSAMXP00000033251 ENSAMXP00000033251 hes4 hes4 ENSAMXP00000032387 ENSAMXP00000032387 hand2 hand2 tead1 tead1 PDE4D PDE4D rspo3 rspo3 LOC103033481 LOC103033481 bmp5 bmp5 ENSAMXP00000030497 ENSAMXP00000030497 Xbp1 Xbp1 ENSAMXP00000029247 ENSAMXP00000029247 LOC111194137 LOC111194137 allc allc bmp3 bmp3 LOC103037538 LOC103037538 Twist2 Twist2 LOC107197907 LOC107197907 W5LQ48_ASTMX W5LQ48_ASTMX Col1a2 Col1a2 LOC103029394 LOC103029394 mstn mstn has2 has2 PRKD3 PRKD3 dkk1 dkk1 tph1 tph1 LOC103029625 LOC103029625 W5LAE5_ASTMX W5LAE5_ASTMX MTMR4 MTMR4 Sp9 Sp9 drd3 drd3 tgfb3 tgfb3 LOC103044978 LOC103044978 Adamtsl2 Adamtsl2 vgll4 vgll4 itga2 itga2 Scx Scx hes1 hes1 mmp13 mmp13 tgfbi tgfbi smad5 smad5 LOC103042974 LOC103042974 LOC103021666 LOC103021666 LOC103024607 LOC103024607 sost sost gsk3b gsk3b W5KLY4_ASTMX W5KLY4_ASTMX traf6 traf6 axin1 axin1 araf araf Lrp5 Lrp5 porcn porcn Lrp2 Lrp2 Sox6 Sox6 sarm1 sarm1 LOC103036701 LOC103036701 W5JXV7_ASTMX W5JXV7_ASTMX myf5 myf5 Runx2 Runx2 W5K0W4_ASTMX W5K0W4_ASTMX dct dct W5K3H2_ASTMX W5K3H2_ASTMX satb2 satb2 tgfb1 tgfb1 map2k1 map2k1 Bmp7 Bmp7 cxcr4 cxcr4 LOC103039568 LOC103039568 pgap1 pgap1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
axin2Uncharacterized protein. (820 aa)
LOC103023202Msh homeobox 2. (240 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
mycnMYCN proto-oncogene, bHLH transcription factor. (438 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
ENSAMXP00000051577Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (399 aa)
myogMyogenin. (254 aa)
LOC103021971Syntaxin binding protein 5b (tomosyn). (1210 aa)
Fgfr3Fibroblast growth factor receptor. (815 aa)
LOC103025657Runt-related transcription factor. (468 aa)
ENSAMXP00000048061Fibroblast growth factor receptor. (806 aa)
ENSAMXP00000047900Protein kinase D3. (646 aa)
TYRTyrosinase. (537 aa)
LOC103032492Receptor protein-tyrosine kinase. (1173 aa)
plekPleckstrin. (352 aa)
dlx3Distal-less homeobox 3b. (265 aa)
bmp4TGF_BETA_2 domain-containing protein. (481 aa)
LOC103031629Receptor protein-tyrosine kinase. (1211 aa)
dlx6Distal-less homeobox 6a. (247 aa)
dlx5Distal-less homeobox 5a. (276 aa)
itgb1Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ENSAMXP00000044581Phosphodiesterase. (677 aa)
asipAgouti signaling protein 1. (129 aa)
LOC103040080Regulator of G protein signaling 4. (208 aa)
tia1Cytotoxic granule-associated RNA binding protein 1, like. (340 aa)
dot1lHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1572 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
prkd2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (923 aa)
nfatc1Nuclear factor of activated T cells 1. (862 aa)
ENSAMXP00000040318Granulin a. (872 aa)
Slc24a5Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (112 aa)
LOC103040843Tyrosinase. (539 aa)
slc20a2Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (662 aa)
ENSAMXP00000038632EBF transcription factor 3a. (583 aa)
ENSAMXP00000038500Apolipoprotein Ea. (321 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC103027532V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
atp6v0a1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (843 aa)
LOC103029324Bone morphogenetic protein 16. (430 aa)
prkd1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (885 aa)
efnb1Ephrin-B1; Belongs to the ephrin family. (344 aa)
atf4Activating transcription factor 4a. (398 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
LOC103034468Cell division cycle 42. (191 aa)
LOC103024286TIMP metallopeptidase inhibitor 2a. (219 aa)
fosbFBJ murine osteosarcoma viral oncogene homolog B. (434 aa)
ENSAMXP00000033251Bone morphogenetic protein 8a. (450 aa)
hes4Hairy-related 9. (295 aa)
ENSAMXP00000032387BHLH domain-containing protein. (246 aa)
hand2Heart and neural crest derivatives expressed 2. (200 aa)
tead1TEA domain family member 1b. (440 aa)
PDE4DPhosphodiesterase. (750 aa)
rspo3R-spondin 3. (314 aa)
LOC103033481Protein kinase D4. (823 aa)
bmp5Bone morphogenetic protein 5. (445 aa)
ENSAMXP00000030497Myocyte enhancer factor 2ca. (397 aa)
Xbp1X-box binding protein 1. (264 aa)
ENSAMXP00000029247Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
LOC111194137BHLH domain-containing protein. (176 aa)
allcAllantoicase. (401 aa)
bmp3Bone morphogenetic protein 3. (442 aa)
LOC103037538Tyrosine-protein kinase receptor. (1389 aa)
Twist2Twist2. (168 aa)
LOC107197907Toll-like receptor 22; Belongs to the Toll-like receptor family. (963 aa)
W5LQ48_ASTMXActinin alpha 3b. (799 aa)
Col1a2Collagen, type I, alpha 2. (1355 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
mstnMyostatin b. (435 aa)
has2Hyaluronan synthase 2. (561 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (889 aa)
dkk1Dickkopf WNT signaling pathway inhibitor 1b. (243 aa)
tph1Tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a. (483 aa)
LOC103029625Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
W5LAE5_ASTMXCalcium/calmodulin-dependent protein kinase 1Da; Belongs to the protein kinase superfamily. (398 aa)
MTMR4Myotubularin related protein 4. (1229 aa)
Sp9Sp9 transcription factor. (443 aa)
drd3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (471 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC103044978Syntaxin binding protein 5a (tomosyn). (1122 aa)
Adamtsl2ADAMTS-like 2. (923 aa)
vgll4Vestigial-like family member 4b. (287 aa)
itga2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family. (1188 aa)
ScxScleraxis bHLH transcription factor a. (195 aa)
hes1Hairy-related 6. (270 aa)
mmp13Matrix metallopeptidase 13b. (462 aa)
tgfbiTransforming growth factor, beta-induced. (677 aa)
smad5Mothers against decapentaplegic homolog. (464 aa)
LOC103042974Axin 2 (conductin, axil). (838 aa)
LOC103021666Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
sostSclerostin. (224 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
W5KLY4_ASTMXDachsous cadherin-related 1b. (3289 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa)
axin1Axin 1. (866 aa)
arafA-Raf proto-oncogene, serine/threonine kinase. (609 aa)
Lrp5Low density lipoprotein receptor-related protein 5. (1518 aa)
porcnPorcupine O-acyltransferase like; Belongs to the membrane-bound acyltransferase family. (446 aa)
Lrp2Low density lipoprotein receptor-related protein 2a. (4559 aa)
Sox6SRY-box transcription factor 6. (787 aa)
sarm1Sterile alpha and TIR motif containing 1. (716 aa)
LOC103036701Endothelial PAS domain protein 1a. (816 aa)
W5JXV7_ASTMXDisco-interacting protein 2 homolog A. (1430 aa)
myf5Myogenic factor. (237 aa)
Runx2Runt-related transcription factor. (417 aa)
W5K0W4_ASTMXEBF transcription factor 3a. (591 aa)
dctDopachrome tautomerase. (518 aa)
W5K3H2_ASTMXHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (418 aa)
satb2DNA-binding protein SATB. (869 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
Bmp7Bone morphogenetic protein 7b. (416 aa)
cxcr4Chemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (356 aa)
LOC103039568SRY-box transcription factor 9b. (480 aa)
pgap1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (940 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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