(17 nodes) (2023) Evolution and function of calponin and transgelin. network (Astyanax mexicanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	parp1	Poly [ADP-ribose] polymerase. (1021 aa)
	LOC103045968	Transgelin; Belongs to the calponin family. (208 aa)
	LOC103024979	Annexin. (333 aa)
	Syk	Tyrosine-protein kinase. (631 aa)
	LOC103033745	Gelsolin a. (738 aa)
	LOC103025197	Notch receptor 1b. (2477 aa)
	LOC103044821	Annexin. (337 aa)
	LOC103041389	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
	LOC103039625	Scinderin like a. (740 aa)
	LOC103034623	Notch receptor 1a. (2450 aa)
	Cd44	Link domain-containing protein. (75 aa)
	ENSAMXP00000039153	Matrix metallopeptidase 9. (629 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2518 aa)
	scin	Scinderin. (725 aa)
	LOC103027267	Gelsolin b. (729 aa)
	W5KK24_ASTMX	Matrix metallopeptidase 9. (683 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd44	ENSAMXP00000039153	ENSAMXP00000040116	ENSAMXP00000039153	Link domain-containing protein.	Matrix metallopeptidase 9.	0.645
Cd44	W5KK24_ASTMX	ENSAMXP00000040116	ENSAMXP00000007936	Link domain-containing protein.	Matrix metallopeptidase 9.	0.645
ENSAMXP00000039153	Cd44	ENSAMXP00000039153	ENSAMXP00000040116	Matrix metallopeptidase 9.	Link domain-containing protein.	0.645
LOC103024979	LOC103044821	ENSAMXP00000045792	ENSAMXP00000050739	Annexin.	Annexin.	0.927
LOC103041389	mapk1	ENSAMXP00000018355	ENSAMXP00000001246	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.948
LOC103044821	LOC103024979	ENSAMXP00000050739	ENSAMXP00000045792	Annexin.	Annexin.	0.927
W5KK24_ASTMX	Cd44	ENSAMXP00000007936	ENSAMXP00000040116	Matrix metallopeptidase 9.	Link domain-containing protein.	0.645
mapk1	LOC103041389	ENSAMXP00000001246	ENSAMXP00000018355	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.948