STRINGSTRING
th th tgfb1 tgfb1 LOC103024607 LOC103024607 tgfb3 tgfb3 shh shh gbx1 gbx1 OTX2 OTX2 ENSAMXP00000035546 ENSAMXP00000035546 LOC103032897 LOC103032897 Ins Ins OTX2-2 OTX2-2 LOC103044969 LOC103044969 isl1 isl1 LOC103042476 LOC103042476 tgfb2 tgfb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thTyrosine hydroxylase. (517 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
gbx1Gastrulation brain homeobox 1. (322 aa)
OTX2Orthodenticle homeobox 2. (271 aa)
ENSAMXP00000035546Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (56 aa)
LOC103032897Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (443 aa)
InsInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (151 aa)
OTX2-2Orthodenticle homeobox 2. (298 aa)
LOC103044969Oxytocin; Belongs to the vasopressin/oxytocin family. (155 aa)
isl1ISL LIM homeobox 1. (332 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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