(68 nodes) Lysine degradation network (Astyanax mexicanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	aass	Aminoadipate-semialdehyde synthase. (930 aa)
	LOC103046024	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	acat2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	ehhadh	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (719 aa)
	Kmt2b	Lysine (K)-specific methyltransferase 2Bb. (3997 aa)
	bbox1	Butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1. (440 aa)
	acat1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (418 aa)
	Nsd1	PWWP domain-containing protein. (1052 aa)
	LOC103026903	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (487 aa)
	LOC103040137	SET domain containing 1A, histone lysine methyltransferase. (2267 aa)
	LOC103022779	Ash1 (absent, small, or homeotic)-like (Drosophila). (2955 aa)
	LOC103028156	SET domain bifurcated histone lysine methyltransferase 1a. (1657 aa)
	hadh	Hydroxyacyl-CoA dehydrogenase. (309 aa)
	aldh16a1	Aldehyde dehydrogenase 16 family, member A1. (795 aa)
	Nsd2	Nuclear receptor binding SET domain protein 2. (1468 aa)
	PRDM6	PR/SET domain 6. (577 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (750 aa)
	aldh7a1	Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family. (540 aa)
	kmt2d	Lysine (K)-specific methyltransferase 2D. (5061 aa)
	dlst	Dihydrolipoamide S-succinyltransferase. (454 aa)
	W5L7W3_ASTMX	RRM domain-containing protein. (1725 aa)
	LOC103023298	Euchromatic histone-lysine N-methyltransferase 1a. (1088 aa)
	LOC103036607	Bromo domain-containing protein. (1917 aa)
	LOC103035446	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (764 aa)
	LOC103025343	SET domain-containing protein. (876 aa)
	dhtkd1	Dehydrogenase E1 and transketolase domain containing 1. (926 aa)
	aldh9a1	Aldehyde dehydrogenase 9 family, member A1b; Belongs to the aldehyde dehydrogenase family. (518 aa)
	LOC103024967	Si:ch211-13f8.2. (602 aa)
	W5LMC2_ASTMX	Euchromatic histone-lysine N-methyltransferase 2. (330 aa)
	W5LMW3_ASTMX	Nuclear receptor binding SET domain protein 1a. (2028 aa)
	setd1b	SET domain containing 1B, histone lysine methyltransferase a. (1849 aa)
	LOC103044252	SET and MYND domain containing 1b. (486 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2886 aa)
	ENSAMXP00000030198	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
	ENSAMXP00000030509	Uncharacterized protein. (345 aa)
	LOC103037645	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3. (727 aa)
	ENSAMXP00000031068	Uncharacterized protein. (116 aa)
	ENSAMXP00000031142	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (408 aa)
	LOC103038801	Cerebral endothelial cell adhesion molecule. (592 aa)
	hykk	Hydroxylysine kinase, tandem duplicate 1. (376 aa)
	LOC103045481	SET domain bifurcated histone lysine methyltransferase 2. (667 aa)
	LOC103034071	SET and MYND domain containing 1a. (479 aa)
	ezh2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (762 aa)
	smyd2	SET and MYND domain containing 2a. (433 aa)
	LOC103043579	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
	echs1	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	Kmt2e	Lysine (K)-specific methyltransferase 2E. (1078 aa)
	gcdh	Glutaryl-CoA dehydrogenase b. (438 aa)
	LOC111197404	Lysine methyltransferase 5Ab. (339 aa)
	plod1	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a. (733 aa)
	dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1572 aa)
	ENSAMXP00000043602	Uncharacterized protein. (576 aa)
	LOC103034196	PR domain containing 2, with ZNF domain a. (1571 aa)
	LOC103031955	SET domain and mariner transposase fusion gene. (287 aa)
	LOC103040252	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
	PIPOX	Pipecolic acid and sarcosine oxidase. (389 aa)
	kmt5b	Lysine methyltransferase 5B. (829 aa)
	setd7	Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (373 aa)
	LOC103042875	Collagen beta(1-O)galactosyltransferase 2. (603 aa)
	ENSAMXP00000046727	Uncharacterized protein. (2715 aa)
	aldh2	Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. (522 aa)
	aadat	Aminoadipate aminotransferase. (439 aa)
	LOC103047782	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	dld	Dihydrolipoyl dehydrogenase. (508 aa)
	Camkmt	Calmodulin-lysine N-methyltransferase. (209 aa)
	colgalt1	Collagen beta(1-O)galactosyltransferase 1. (608 aa)
	LOC103032474	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2. (756 aa)
	LOC103033426	PR domain containing 9. (855 aa)

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Camkmt	ENSAMXP00000030509	ENSAMXP00000051378	ENSAMXP00000030509	Calmodulin-lysine N-methyltransferase.	Uncharacterized protein.	0.659
Camkmt	ENSAMXP00000031068	ENSAMXP00000051378	ENSAMXP00000031068	Calmodulin-lysine N-methyltransferase.	Uncharacterized protein.	0.658
Camkmt	ENSAMXP00000031142	ENSAMXP00000051378	ENSAMXP00000031142	Calmodulin-lysine N-methyltransferase.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.684
Camkmt	ENSAMXP00000043602	ENSAMXP00000051378	ENSAMXP00000043602	Calmodulin-lysine N-methyltransferase.	Uncharacterized protein.	0.659
Camkmt	ENSAMXP00000046727	ENSAMXP00000051378	ENSAMXP00000046727	Calmodulin-lysine N-methyltransferase.	Uncharacterized protein.	0.658
Camkmt	EZH1	ENSAMXP00000051378	ENSAMXP00000013017	Calmodulin-lysine N-methyltransferase.	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.674
Camkmt	Kmt2b	ENSAMXP00000051378	ENSAMXP00000004791	Calmodulin-lysine N-methyltransferase.	Lysine (K)-specific methyltransferase 2Bb.	0.658
Camkmt	Kmt2e	ENSAMXP00000051378	ENSAMXP00000037378	Calmodulin-lysine N-methyltransferase.	Lysine (K)-specific methyltransferase 2E.	0.658
Camkmt	LOC103022779	ENSAMXP00000051378	ENSAMXP00000010273	Calmodulin-lysine N-methyltransferase.	Ash1 (absent, small, or homeotic)-like (Drosophila).	0.693
Camkmt	LOC103023298	ENSAMXP00000051378	ENSAMXP00000016487	Calmodulin-lysine N-methyltransferase.	Euchromatic histone-lysine N-methyltransferase 1a.	0.685
Camkmt	LOC103025343	ENSAMXP00000051378	ENSAMXP00000017767	Calmodulin-lysine N-methyltransferase.	SET domain-containing protein.	0.660
Camkmt	LOC103028156	ENSAMXP00000051378	ENSAMXP00000010304	Calmodulin-lysine N-methyltransferase.	SET domain bifurcated histone lysine methyltransferase 1a.	0.677
Camkmt	LOC103031955	ENSAMXP00000051378	ENSAMXP00000044554	Calmodulin-lysine N-methyltransferase.	SET domain and mariner transposase fusion gene.	0.660
Camkmt	LOC103032474	ENSAMXP00000051378	ENSAMXP00000053482	Calmodulin-lysine N-methyltransferase.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2.	0.900
Camkmt	LOC103033426	ENSAMXP00000051378	ENSAMXP00000054485	Calmodulin-lysine N-methyltransferase.	PR domain containing 9.	0.661
Camkmt	LOC103034071	ENSAMXP00000051378	ENSAMXP00000033628	Calmodulin-lysine N-methyltransferase.	SET and MYND domain containing 1a.	0.674
Camkmt	LOC103034196	ENSAMXP00000051378	ENSAMXP00000043707	Calmodulin-lysine N-methyltransferase.	PR domain containing 2, with ZNF domain a.	0.685
Camkmt	LOC103036607	ENSAMXP00000051378	ENSAMXP00000016705	Calmodulin-lysine N-methyltransferase.	Bromo domain-containing protein.	0.693
Camkmt	LOC103037645	ENSAMXP00000051378	ENSAMXP00000030724	Calmodulin-lysine N-methyltransferase.	Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3.	0.900
Camkmt	LOC103040137	ENSAMXP00000051378	ENSAMXP00000009797	Calmodulin-lysine N-methyltransferase.	SET domain containing 1A, histone lysine methyltransferase.	0.674