STRINGSTRING
LOC103031338 LOC103031338 W5JYR7_ASTMX W5JYR7_ASTMX LOC103034175 LOC103034175 LOC103021856 LOC103021856 mapk1 mapk1 tgfb1 tgfb1 smad6 smad6 LOC103026097 LOC103026097 rps6kb2 rps6kb2 LOC103041202 LOC103041202 W5KF46_ASTMX W5KF46_ASTMX LOC103031445 LOC103031445 LOC103031498 LOC103031498 LOC103032850 LOC103032850 LOC103031419 LOC103031419 LOC103044365 LOC103044365 LOC103040899 LOC103040899 rbl1 rbl1 LOC103024607 LOC103024607 gdf5 gdf5 ACVR1 ACVR1 smad5 smad5 LOC103032568 LOC103032568 chrd chrd Gdf7 Gdf7 ep300 ep300 tgfb3 tgfb3 SMURF2 SMURF2 nodal nodal LOC103045580 LOC103045580 tfdp1 tfdp1 LOC103027116 LOC103027116 LOC103028705 LOC103028705 W5LD66_ASTMX W5LD66_ASTMX LOC103043735 LOC103043735 LOC103041389 LOC103041389 LOC103022359 LOC103022359 LOC103029394 LOC103029394 W5LJ85_ASTMX W5LJ85_ASTMX W5LJD2_ASTMX W5LJD2_ASTMX tgfbr2 tgfbr2 LOC103023108 LOC103023108 acvr2b acvr2b LOC103026512 LOC103026512 Grem2 Grem2 LOC103029721 LOC103029721 NBL1 NBL1 LOC103035375 LOC103035375 LOC103032572 LOC103032572 LOC103042113 LOC103042113 THSD4 THSD4 Ppp2cb Ppp2cb ppp2ca ppp2ca LOC103038302 LOC103038302 Bmpr2 Bmpr2 bmp6 bmp6 LOC103032351 LOC103032351 rgma rgma bmp5 bmp5 bmpr1b bmpr1b LOC103027004 LOC103027004 LOC103035751 LOC103035751 dcn dcn LOC103035022 LOC103035022 rps6kb1 rps6kb1 LOC111194478 LOC111194478 ENSAMXP00000033251 ENSAMXP00000033251 hamp hamp LOC103029431 LOC103029431 INHBC INHBC rgmb rgmb cul1 cul1 smad2 smad2 LOC103028976 LOC103028976 LOC103045393 LOC103045393 LOC103037767 LOC103037767 LOC111189396 LOC111189396 LOC103038167 LOC103038167 LOC103029324 LOC103029324 LOC103030936 LOC103030936 LOC103033997 LOC103033997 e2f5 e2f5 LOC103044553 LOC103044553 smad1 smad1 ENSAMXP00000040747 ENSAMXP00000040747 smurf1 smurf1 LOC103033691 LOC103033691 id3 id3 Crebbp Crebbp LOC103042559 LOC103042559 INHBB INHBB LOC103035456 LOC103035456 skp1 skp1 LOC103025122 LOC103025122 bmp4 bmp4 LOC103041954 LOC103041954 Amh Amh LOC103027811 LOC103027811 LOC103027457 LOC103027457 Rbx1 Rbx1 ENSAMXP00000047553 ENSAMXP00000047553 LOC103035745 LOC103035745 hjv hjv LOC103023889 LOC103023889 LOC103041475 LOC103041475 LOC103025967 LOC103025967 fst fst Thbs1 Thbs1 sp1 sp1 LOC103044657 LOC103044657 smad7 smad7 LOC103042476 LOC103042476 ACVR1C ACVR1C LOC103039137 LOC103039137 ENSAMXP00000052165 ENSAMXP00000052165 LOC103045951 LOC103045951 LOC103047891 LOC103047891 tgfb2 tgfb2 LOC103038757 LOC103038757 id4 id4 Bmp7 Bmp7 pitx2 pitx2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103031338Ras homolog family member Cb. (195 aa)
W5JYR7_ASTMXLeft-right determination factor. (381 aa)
LOC103034175Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (496 aa)
LOC103021856Bone morphogenetic protein 2a. (405 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
smad6Mothers against decapentaplegic homolog. (480 aa)
LOC103026097Inhibin subunit beta B. (387 aa)
rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (464 aa)
LOC103041202Inhibitor of DNA binding 2b. (133 aa)
W5KF46_ASTMXTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (561 aa)
LOC103031445Thrombospondin 1b. (1178 aa)
LOC103031498Fibromodulin a. (339 aa)
LOC103032850Protein phosphatase 2, regulatory subunit A, beta a. (589 aa)
LOC103031419Neogenin 1a. (1407 aa)
LOC103044365E1A binding protein p300 a. (2671 aa)
LOC103040899Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
rbl1Retinoblastoma-like 1 (p107). (1053 aa)
LOC103024607Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
gdf5Growth differentiation factor 5. (431 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (679 aa)
smad5Mothers against decapentaplegic homolog. (464 aa)
LOC103032568Tumor necrosis factor a (TNF superfamily, member 2). (234 aa)
chrdChordin; Belongs to the chordin family. (945 aa)
Gdf7Growth differentiation factor 7. (429 aa)
ep300E1A binding protein p300 b. (2652 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
SMURF2E3 ubiquitin-protein ligase. (761 aa)
nodalNodal-related 2. (373 aa)
LOC103045580Homeobox domain-containing protein. (408 aa)
tfdp1Transcription factor. (405 aa)
LOC103027116Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
LOC103028705Ras homolog gene family, member Aa. (193 aa)
W5LD66_ASTMXMothers against decapentaplegic homolog. (573 aa)
LOC103043735Inhibitor of DNA binding 2a. (134 aa)
LOC103041389Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
LOC103022359Mothers against decapentaplegic homolog. (587 aa)
LOC103029394Mothers against decapentaplegic homolog. (544 aa)
W5LJ85_ASTMXZinc finger, FYVE domain containing 9a. (1227 aa)
W5LJD2_ASTMXReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
tgfbr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
LOC103023108Southpaw. (418 aa)
acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LOC103026512Gremlin 2, DAN family BMP antagonist a. (195 aa)
Grem2Gremlin 2, DAN family BMP antagonist b. (166 aa)
LOC103029721BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b. (276 aa)
NBL1NBL1, DAN family BMP antagonist. (271 aa)
LOC103035375Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (519 aa)
LOC103032572Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
LOC103042113Bone morphogenetic protein 7a. (403 aa)
THSD4Thrombospondin type 1 domain containing 4. (959 aa)
Ppp2cbSerine/threonine-protein phosphatase. (309 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC103038302Inhibin subunit beta Ab. (431 aa)
Bmpr2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1070 aa)
bmp6Bone morphogenetic protein 6. (427 aa)
LOC103032351Zgc:113307. (363 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (460 aa)
bmp5Bone morphogenetic protein 5. (445 aa)
bmpr1bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
LOC103027004Mothers against decapentaplegic homolog. (424 aa)
LOC103035751Follistatin b. (362 aa)
dcnDecorin; May affect the rate of fibrils formation. (364 aa)
LOC103035022Growth differentiation factor 6a. (406 aa)
rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
LOC111194478Cullin 1a; Belongs to the cullin family. (777 aa)
ENSAMXP00000033251Bone morphogenetic protein 8a. (450 aa)
hampUncharacterized protein. (99 aa)
LOC103029431Uncharacterized protein. (193 aa)
INHBCInhibin subunit beta C. (389 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (439 aa)
cul1Cullin 1b; Belongs to the cullin family. (772 aa)
smad2Mothers against decapentaplegic homolog. (468 aa)
LOC103028976Bone morphogenetic protein 2b. (445 aa)
LOC103045393BHLH domain-containing protein. (125 aa)
LOC103037767TGFB-induced factor homeobox 1. (253 aa)
LOC111189396ANK_REP_REGION domain-containing protein. (152 aa)
LOC103038167Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (392 aa)
LOC103029324Bone morphogenetic protein 16. (430 aa)
LOC103030936BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (265 aa)
LOC103033997Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (393 aa)
e2f5E2F transcription factor 5. (375 aa)
LOC103044553Gremlin 1a, DAN family BMP antagonist. (171 aa)
smad1Mothers against decapentaplegic homolog. (488 aa)
ENSAMXP00000040747Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (578 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
LOC103033691Inhibin subunit beta Aa. (392 aa)
id3Inhibitor of DNA binding 3. (112 aa)
CrebbpCREB binding protein a. (2140 aa)
LOC103042559Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
INHBBInhibin subunit beta B. (389 aa)
LOC103035456Ras homolog family member Ca. (193 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC103025122Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
bmp4TGF_BETA_2 domain-containing protein. (481 aa)
LOC103041954Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
AmhAnti-Mullerian hormone. (551 aa)
LOC103027811Mothers against decapentaplegic homolog. (425 aa)
LOC103027457Ras homolog gene family, member Ab. (193 aa)
Rbx1Ring-box 1, E3 ubiquitin protein ligase. (123 aa)
ENSAMXP00000047553Nodal-related 1. (115 aa)
LOC103035745Growth differentiation factor 6b. (398 aa)
hjvHemojuvelin BMP co-receptor. (460 aa)
LOC103023889Fibromodulin b. (366 aa)
LOC103041475Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1048 aa)
LOC103025967Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
fstFollistatin a. (347 aa)
Thbs1Thrombospondin 1a. (1133 aa)
sp1Uncharacterized protein. (678 aa)
LOC103044657RGM domain family, member D. (491 aa)
smad7Mothers against decapentaplegic homolog. (390 aa)
LOC103042476Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (495 aa)
LOC103039137Anti-dorsalizing morphogenic protein. (459 aa)
ENSAMXP00000052165PLAC domain-containing protein. (230 aa)
LOC103045951Transcription factor. (407 aa)
LOC103047891Inhibitor of DNA binding 1, HLH protein. (131 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
LOC103038757E2F transcription factor 4. (150 aa)
id4Inhibitor of DNA binding 4. (125 aa)
Bmp7Bone morphogenetic protein 7b. (416 aa)
pitx2Homeobox protein. (300 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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