STRINGSTRING
Wnt10a Wnt10a fzd3 fzd3 LOC103023536 LOC103023536 mapk1 mapk1 creb3l2 creb3l2 LOC103043104 LOC103043104 dct dct kit kit LOC103034575 LOC103034575 map2k1 map2k1 fzd4 fzd4 LOC103022374 LOC103022374 PLCB1 PLCB1 LOC103034112 LOC103034112 LOC103033963 LOC103033963 W5KJA8_ASTMX W5KJA8_ASTMX LOC103044365 LOC103044365 LOC103022398 LOC103022398 CALML6 CALML6 gsk3b gsk3b W5KP74_ASTMX W5KP74_ASTMX adcy8 adcy8 LOC103021666 LOC103021666 LOC103031589 LOC103031589 pomc pomc LOC103025973 LOC103025973 dvl2 dvl2 LOC103035729 LOC103035729 ep300 ep300 PLCB4 PLCB4 LOC103033987 LOC103033987 W5L6U8_ASTMX W5L6U8_ASTMX Fzd10 Fzd10 LOC103029625 LOC103029625 LOC103038241 LOC103038241 LOC103041389 LOC103041389 LOC103029357 LOC103029357 adcy7 adcy7 W5LQG8_ASTMX W5LQG8_ASTMX W5LQM2_ASTMX W5LQM2_ASTMX LOC103027103 LOC103027103 LOC103031621 LOC103031621 FZD7 FZD7 W5LSI7_ASTMX W5LSI7_ASTMX LOC103027133 LOC103027133 W5LU60_ASTMX W5LU60_ASTMX Fzd5 Fzd5 Creb3l3 Creb3l3 prkacb prkacb LOC103035761 LOC103035761 wnt9b wnt9b LOC103024012 LOC103024012 kitlg kitlg LOC111193748 LOC111193748 gnao1 gnao1 ENSAMXP00000029017 ENSAMXP00000029017 ENSAMXP00000029247 ENSAMXP00000029247 LOC103043510 LOC103043510 PLCB2 PLCB2 wnt7a wnt7a Wnt2b Wnt2b ENSAMXP00000032836 ENSAMXP00000032836 LOC103042747 LOC103042747 LOC103034748 LOC103034748 LOC103043574 LOC103043574 ENSAMXP00000034556 ENSAMXP00000034556 LOC103042896 LOC103042896 LOC111191807 LOC111191807 Wnt4 Wnt4 LOC103032713 LOC103032713 LOC103038704 LOC103038704 ENSAMXP00000038286 ENSAMXP00000038286 adcy9 adcy9 LOC103040843 LOC103040843 ENSAMXP00000040119 ENSAMXP00000040119 wnt16 wnt16 Fzd6 Fzd6 calm2 calm2 LOC103032770 LOC103032770 LOC103027930 LOC103027930 ENSAMXP00000042370 ENSAMXP00000042370 LOC103024963 LOC103024963 LOC103036102 LOC103036102 Crebbp Crebbp wnt8b wnt8b map2k2 map2k2 asip asip adcy5 adcy5 wnt5a wnt5a lef1 lef1 hras hras prkcb prkcb ENSAMXP00000045240 ENSAMXP00000045240 tcf7l2 tcf7l2 wnt6 wnt6 LOC103023241 LOC103023241 LOC103026929 LOC103026929 Adcy3 Adcy3 TYR TYR wnt10b wnt10b LOC103045689 LOC103045689 nras nras PLCB4-2 PLCB4-2 Wnt1 Wnt1 LOC103036916 LOC103036916 ctnnb1 ctnnb1 wnt7b wnt7b LOC103040103 LOC103040103 LOC103042808 LOC103042808 LOC103037950 LOC103037950 LOC103046093 LOC103046093 Fzd2 Fzd2 ENSAMXP00000053457 ENSAMXP00000053457 LOC103037168 LOC103037168 creb1 creb1 CREB3L4 CREB3L4 creb3l1 creb3l1 ENSAMXP00000054703 ENSAMXP00000054703
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
fzd3Frizzled class receptor 3b; Belongs to the G-protein coupled receptor Fz/Smo family. (689 aa)
LOC103023536Zgc:55558. (187 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (410 aa)
creb3l2cAMP responsive element binding protein 3-like 2. (530 aa)
LOC103043104Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (444 aa)
dctDopachrome tautomerase. (518 aa)
kitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
LOC103034575Catenin, beta 2. (779 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (526 aa)
LOC103022374Transcription factor 7 like 1b. (583 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1250 aa)
LOC103034112Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
LOC103033963Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
W5KJA8_ASTMXProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (402 aa)
LOC103044365E1A binding protein p300 a. (2671 aa)
LOC103022398Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
CALML6Calmodulin like 6. (165 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
W5KP74_ASTMXAdenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1228 aa)
LOC103021666Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOC103031589Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1183 aa)
pomcProopiomelanocortin a. (268 aa)
LOC103025973Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
dvl2Dishevelled segment polarity protein 2. (752 aa)
LOC103035729Dishevelled segment polarity protein 1a. (731 aa)
ep300E1A binding protein p300 b. (2652 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
LOC1030339871-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
W5L6U8_ASTMXProtein kinase C. (646 aa)
Fzd10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (527 aa)
LOC103029625Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
LOC103038241V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC103041389Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
LOC1030293571-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1251 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1156 aa)
W5LQG8_ASTMXTyrosinase related protein 1. (479 aa)
W5LQM2_ASTMXMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (962 aa)
LOC103027103Tyrosinase-related protein 1b. (526 aa)
LOC103031621Adenylate cyclase 4. (1303 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa)
W5LSI7_ASTMXFrizzled class receptor 9a; Belongs to the G-protein coupled receptor Fz/Smo family. (596 aa)
LOC103027133Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa)
W5LU60_ASTMXFrizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (561 aa)
Fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
Creb3l3cAMP responsive element binding protein 3-like 3b. (434 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (395 aa)
LOC103035761Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a. (354 aa)
wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
LOC103024012Uncharacterized protein. (319 aa)
kitlgKit ligand a. (271 aa)
LOC111193748Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (374 aa)
gnao1Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a. (354 aa)
ENSAMXP00000029017Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (203 aa)
ENSAMXP00000029247Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
LOC103043510G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (421 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1187 aa)
wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
Wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (558 aa)
ENSAMXP00000032836Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b. (285 aa)
LOC103042747Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1174 aa)
LOC103034748Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
LOC103043574Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (420 aa)
ENSAMXP00000034556Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
LOC103042896Dishevelled segment polarity protein 3a. (676 aa)
LOC111191807Guanine nucleotide binding protein (G protein), alpha 14. (353 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LOC103032713Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1. (628 aa)
LOC103038704Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
ENSAMXP00000038286Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (299 aa)
adcy9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1417 aa)
LOC103040843Tyrosinase. (539 aa)
ENSAMXP00000040119Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (404 aa)
wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
Fzd6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (704 aa)
calm2Calmodulin 2b, (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC103032770Calmodulin-like 4b. (153 aa)
LOC103027930Raf-1 proto-oncogene, serine/threonine kinase b. (636 aa)
ENSAMXP00000042370Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LOC103024963Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (419 aa)
LOC103036102Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CrebbpCREB binding protein a. (2140 aa)
wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
map2k2Mitogen-activated protein kinase kinase 2b; Belongs to the protein kinase superfamily. (394 aa)
asipAgouti signaling protein 1. (129 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1205 aa)
wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
lef1Lymphoid enhancer-binding factor 1. (384 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
prkcbProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
ENSAMXP00000045240Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (281 aa)
tcf7l2Transcription factor 7 like 2. (630 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC103023241Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
LOC103026929Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
Adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1141 aa)
TYRTyrosinase. (537 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (427 aa)
LOC103045689Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
nrasNRAS proto-oncogene, GTPase. (188 aa)
PLCB4-21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1225 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (403 aa)
LOC103036916Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1150 aa)
ctnnb1Catenin (cadherin-associated protein), beta 1. (790 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC103040103HRas proto-oncogene, GTPase b. (189 aa)
LOC103042808Uncharacterized protein. (359 aa)
LOC103037950Kit ligand b. (267 aa)
LOC103046093Dishevelled segment polarity protein 1b. (726 aa)
Fzd2Frizzled class receptor 2. (240 aa)
ENSAMXP00000053457Calmodulin-like 4a. (117 aa)
LOC103037168cAMP responsive element binding protein 3-like 3 like. (469 aa)
creb1cAMP responsive element binding protein 1b. (334 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (498 aa)
creb3l1cAMP responsive element binding protein 3-like 1. (521 aa)
ENSAMXP00000054703Melanocyte inducing transcription factor a. (497 aa)
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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