22 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108271110	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (550 aa)
	LOC108255052	Tumor necrosis factor receptor superfamily member 1B-like. (418 aa)
	tradd	Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (332 aa)
	birc7	Baculoviral IAP repeat-containing protein 7-like. (397 aa)
	LOC108262934	Toll-like receptor 4. (472 aa)
	LOC108271158	Receptor-interacting serine/threonine-protein kinase 2-like isoform X1. (531 aa)
	LOC108255825	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (581 aa)
	tnfrsf1a	Tumor necrosis factor receptor superfamily member 1A. (402 aa)
	nod1	Nucleotide-binding oligomerization domain-containing protein 1. (946 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (579 aa)
	LOC108264960	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa)
	map3k7	Mitogen-activated protein kinase kinase kinase 7. (550 aa)
	tab2	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (673 aa)
	ikbkg	NF-kappa-B essential modulator. (568 aa)
	tab3	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (554 aa)
	nod2	Nucleotide-binding oligomerization domain-containing protein 2. (981 aa)
	traf2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (529 aa)
	cyld	Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (768 aa)
	tab1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (495 aa)
	plekhg5	Pleckstrin homology domain-containing family G member 5 isoform X7. (1192 aa)
	map3k20	Mitogen-activated protein kinase kinase kinase MLT. (796 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108255052	LOC108255825	ENSIPUP00000005601	ENSIPUP00000008445	Tumor necrosis factor receptor superfamily member 1B-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.979
LOC108255052	LOC108264960	ENSIPUP00000005601	ENSIPUP00000014783	Tumor necrosis factor receptor superfamily member 1B-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.802
LOC108255052	LOC108271110	ENSIPUP00000005601	ENSIPUP00000003064	Tumor necrosis factor receptor superfamily member 1B-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.747
LOC108255052	birc7	ENSIPUP00000005601	ENSIPUP00000007700	Tumor necrosis factor receptor superfamily member 1B-like.	Baculoviral IAP repeat-containing protein 7-like.	0.557
LOC108255052	tnfrsf1a	ENSIPUP00000005601	ENSIPUP00000011585	Tumor necrosis factor receptor superfamily member 1B-like.	Tumor necrosis factor receptor superfamily member 1A.	0.714
LOC108255052	tradd	ENSIPUP00000005601	ENSIPUP00000007385	Tumor necrosis factor receptor superfamily member 1B-like.	Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2.	0.412
LOC108255052	traf2	ENSIPUP00000005601	ENSIPUP00000024025	Tumor necrosis factor receptor superfamily member 1B-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.979
LOC108255052	traf6	ENSIPUP00000005601	ENSIPUP00000032978	Tumor necrosis factor receptor superfamily member 1B-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.519
LOC108255825	LOC108255052	ENSIPUP00000008445	ENSIPUP00000005601	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Tumor necrosis factor receptor superfamily member 1B-like.	0.979
LOC108255825	LOC108262934	ENSIPUP00000008445	ENSIPUP00000007781	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Toll-like receptor 4.	0.695
LOC108255825	LOC108264960	ENSIPUP00000008445	ENSIPUP00000014783	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.911
LOC108255825	LOC108271110	ENSIPUP00000008445	ENSIPUP00000003064	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.963
LOC108255825	LOC108271158	ENSIPUP00000008445	ENSIPUP00000007939	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Receptor-interacting serine/threonine-protein kinase 2-like isoform X1.	0.950
LOC108255825	birc7	ENSIPUP00000008445	ENSIPUP00000007700	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Baculoviral IAP repeat-containing protein 7-like.	0.745
LOC108255825	cyld	ENSIPUP00000008445	ENSIPUP00000024046	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	0.589
LOC108255825	ikbkg	ENSIPUP00000008445	ENSIPUP00000019557	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	NF-kappa-B essential modulator.	0.769
LOC108255825	map3k20	ENSIPUP00000008445	ENSIPUP00000029930	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Mitogen-activated protein kinase kinase kinase MLT.	0.546
LOC108255825	map3k7	ENSIPUP00000008445	ENSIPUP00000015661	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Mitogen-activated protein kinase kinase kinase 7.	0.663
LOC108255825	plekhg5	ENSIPUP00000008445	ENSIPUP00000028602	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Pleckstrin homology domain-containing family G member 5 isoform X7.	0.456
LOC108255825	ripk2	ENSIPUP00000008445	ENSIPUP00000013628	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.950