46 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108268977	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (243 aa)
	LOC108280865	Vascular endothelial growth factor A-A-like; Belongs to the PDGF/VEGF growth factor family. (185 aa)
	mdk	Midkine. (146 aa)
	ENSIPUP00000001685	Prokineticin 2. (107 aa)
	LOC108260470	RNA polymerase II degradation factor 1-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (581 aa)
	vegfc	Vascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (399 aa)
	apela	Apelin receptor early endogenous ligand. (60 aa)
	nf1	Neurofibromin isoform X5. (2745 aa)
	aplnr	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	LOC108264167	Bone morphogenetic protein 2-like. (420 aa)
	LOC108260832	Fibroblast growth factor-binding protein 1-like. (201 aa)
	prok1	Prokineticin-1. (105 aa)
	bmp4	Bone morphogenetic protein 4. (402 aa)
	ecm1	Extracellular matrix protein 1 isoform X4. (648 aa)
	lrg1	Leucine-rich alpha-2-glycoprotein isoform X6. (327 aa)
	LOC108270647	VIP peptides-like. (190 aa)
	scg2	Secretogranin-2. (591 aa)
	LOC108274967	midkine-B-like. (144 aa)
	LOC108259423	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (476 aa)
	f3	Tissue factor. (293 aa)
	jcad	Junctional protein associated with coronary artery disease. (1489 aa)
	jun	Transcription factor AP-1; Belongs to the bZIP family. (324 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1058 aa)
	LOC108267848	Transcription factor AP-1-like. (275 aa)
	LOC108280860	Junctional protein associated with coronary artery disease-like. (1958 aa)
	LOC108280419	Tissue factor-like. (250 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
	vegfa	Vascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (252 aa)
	sirt6	NAD-dependent protein deacetylase sirtuin-6 isoform X1. (386 aa)
	sirt1	NAD-dependent protein deacetylase sirtuin-1 isoform X3. (731 aa)
	LOC108260086	Transcription factor AP-1-like. (343 aa)
	LOC108262931	VIP peptides-like. (120 aa)
	LOC108260337	LOW QUALITY PROTEIN: ribonuclease-like 3; Belongs to the pancreatic ribonuclease family. (143 aa)
	LOC108279200	Vascular endothelial growth factor A-like; Belongs to the PDGF/VEGF growth factor family. (136 aa)
	LOC108276969	Neurofibromin isoform X3. (2756 aa)
	aggf1	Angiogenic factor with G patch and FHA domains 1 isoform X1. (758 aa)
	LOC108272897	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
	rptor	Regulatory-associated protein of mTOR isoform X1. (1351 aa)
	LOC108270063	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1. (838 aa)
	LOC108257789	Disintegrin and metalloproteinase domain-containing protein 17-like. (833 aa)
	pgf	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (164 aa)
	il10	Interleukin-10. (223 aa)
	LOC108277359	Apelin receptor B-like; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	htr2b	5-hydroxytryptamine receptor 2B. (445 aa)
	sp1	Transcription factor Sp1. (621 aa)
	mydgf	Myeloid-derived growth factor. (178 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108257789	LOC108270063	ENSIPUP00000035010	ENSIPUP00000034998	Disintegrin and metalloproteinase domain-containing protein 17-like.	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1.	0.901
LOC108259423	LOC108279200	ENSIPUP00000015408	ENSIPUP00000030754	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor A-like; Belongs to the PDGF/VEGF growth factor family.	0.912
LOC108259423	pgf	ENSIPUP00000015408	ENSIPUP00000035786	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.916
LOC108259423	vegfa	ENSIPUP00000015408	ENSIPUP00000025653	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.906
LOC108259423	vegfc	ENSIPUP00000015408	ENSIPUP00000003657	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.934
LOC108260086	LOC108267848	ENSIPUP00000027461	ENSIPUP00000019327	Transcription factor AP-1-like.	Transcription factor AP-1-like.	0.903
LOC108260086	jun	ENSIPUP00000027461	ENSIPUP00000018160	Transcription factor AP-1-like.	Transcription factor AP-1; Belongs to the bZIP family.	0.900
LOC108260086	sirt1	ENSIPUP00000027461	ENSIPUP00000027456	Transcription factor AP-1-like.	NAD-dependent protein deacetylase sirtuin-1 isoform X3.	0.575
LOC108260086	sp1	ENSIPUP00000027461	ENSIPUP00000036790	Transcription factor AP-1-like.	Transcription factor Sp1.	0.676
LOC108260832	fgf7	ENSIPUP00000005922	ENSIPUP00000024091	Fibroblast growth factor-binding protein 1-like.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.840
LOC108262931	LOC108270647	ENSIPUP00000027496	ENSIPUP00000014701	VIP peptides-like.	VIP peptides-like.	0.903
LOC108264167	LOC108272897	ENSIPUP00000005898	ENSIPUP00000032237	Bone morphogenetic protein 2-like.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.972
LOC108264167	bmpr2	ENSIPUP00000005898	ENSIPUP00000018349	Bone morphogenetic protein 2-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.972
LOC108267848	LOC108260086	ENSIPUP00000019327	ENSIPUP00000027461	Transcription factor AP-1-like.	Transcription factor AP-1-like.	0.903
LOC108267848	jun	ENSIPUP00000019327	ENSIPUP00000018160	Transcription factor AP-1-like.	Transcription factor AP-1; Belongs to the bZIP family.	0.905
LOC108267848	sirt1	ENSIPUP00000019327	ENSIPUP00000027456	Transcription factor AP-1-like.	NAD-dependent protein deacetylase sirtuin-1 isoform X3.	0.575
LOC108267848	sp1	ENSIPUP00000019327	ENSIPUP00000036790	Transcription factor AP-1-like.	Transcription factor Sp1.	0.676
LOC108268977	pgf	ENSIPUP00000000556	ENSIPUP00000035786	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.590
LOC108268977	vegfc	ENSIPUP00000000556	ENSIPUP00000003657	Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.555
LOC108270063	LOC108257789	ENSIPUP00000034998	ENSIPUP00000035010	Disintegrin and metalloproteinase domain-containing protein 17-like isoform X1.	Disintegrin and metalloproteinase domain-containing protein 17-like.	0.901