48 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCN3	Protein NOV-like. (315 aa)
	cytl1	Cytokine-like protein 1. (192 aa)
	LOC108272268	High mobility group protein HMGI-C-like. (103 aa)
	rb1	Retinoblastoma-associated protein. (902 aa)
	trip11	Thyroid receptor-interacting protein 11. (1983 aa)
	LOC108279384	Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
	sox6	Transcription factor SOX-6 isoform X7. (759 aa)
	LOC108265471	AT-rich interactive domain-containing protein 5A-like. (563 aa)
	LOC108274807	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
	LOC108264167	Bone morphogenetic protein 2-like. (420 aa)
	runx2	Runt-related transcription factor. (472 aa)
	ext2	Exostosin-2; Belongs to the glycosyltransferase 47 family. (719 aa)
	bmpr1b	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
	ift80	Intraflagellar transport protein 80 homolog isoform X1. (836 aa)
	bmp4	Bone morphogenetic protein 4. (402 aa)
	mef2d	Myocyte-specific enhancer factor 2D isoform X3. (552 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1075 aa)
	anxa6	Annexin. (662 aa)
	LOC108280750	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	runx1	Runt-related transcription factor. (508 aa)
	LOC108274296	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
	LOC108274431	Fibroblast growth factor 18-like isoform X1; Belongs to the heparin-binding growth factors family. (208 aa)
	sulf2	Extracellular sulfatase Sulf-2 isoform X1. (1057 aa)
	ecm1	Extracellular matrix protein 1 isoform X4. (648 aa)
	ccn2	Connective Tissue growth factor. (344 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1058 aa)
	ENSIPUP00000018352	annotation not available (131 aa)
	sulf1	Extracellular sulfatase Sulf-1 isoform X2. (1091 aa)
	smpd3	Sphingomyelin phosphodiesterase 3. (688 aa)
	LOC108277729	Tsukushin-like isoform X1. (374 aa)
	ENSIPUP00000021843	Secreted frizzled-related protein 2 like. (231 aa)
	LOC108278262	Serpin H1-like; Belongs to the serpin family. (405 aa)
	snx19	Sorting nexin-19. (973 aa)
	creb3l2	Cyclic AMP-responsive element-binding protein 3-like protein 2. (536 aa)
	bmpr1a	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (550 aa)
	hmga2	High mobility group protein HMGI-C isoform X2. (109 aa)
	gnptab	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. (1235 aa)
	tgfbr2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (572 aa)
	LOC108258149	Runt-related transcription factor. (527 aa)
	runx3	Runt-related transcription factor. (446 aa)
	LOC108268415	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	tsku	Tsukushin. (346 aa)
	LOC108277285	Serpin peptidase inhibitor clade H member 1a; Belongs to the serpin family. (403 aa)
	LOC108272897	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
	LOC108279752	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	ENSIPUP00000036008	annotation not available (118 aa)
	wnt5a	Wingless-type MMTV integration site family, member 5. (163 aa)
	LOC108265003	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (114 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSIPUP00000021843	LOC108265003	ENSIPUP00000021843	ENSIPUP00000037241	Secreted frizzled-related protein 2 like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.577
ENSIPUP00000021843	LOC108279752	ENSIPUP00000021843	ENSIPUP00000034521	Secreted frizzled-related protein 2 like.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.577
ENSIPUP00000021843	wnt5a	ENSIPUP00000021843	ENSIPUP00000036586	Secreted frizzled-related protein 2 like.	Wingless-type MMTV integration site family, member 5.	0.577
ENSIPUP00000036008	sox6	ENSIPUP00000036008	ENSIPUP00000005000	annotation not available	Transcription factor SOX-6 isoform X7.	0.752
LOC108258149	LOC108264167	ENSIPUP00000027746	ENSIPUP00000005898	Runt-related transcription factor.	Bone morphogenetic protein 2-like.	0.448
LOC108258149	LOC108279384	ENSIPUP00000027746	ENSIPUP00000003544	Runt-related transcription factor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.546
LOC108258149	LOC108280750	ENSIPUP00000027746	ENSIPUP00000009954	Runt-related transcription factor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.546
LOC108258149	bmp4	ENSIPUP00000027746	ENSIPUP00000008975	Runt-related transcription factor.	Bone morphogenetic protein 4.	0.415
LOC108258149	rb1	ENSIPUP00000027746	ENSIPUP00000001212	Runt-related transcription factor.	Retinoblastoma-associated protein.	0.563
LOC108264167	LOC108258149	ENSIPUP00000005898	ENSIPUP00000027746	Bone morphogenetic protein 2-like.	Runt-related transcription factor.	0.448
LOC108264167	LOC108272897	ENSIPUP00000005898	ENSIPUP00000032237	Bone morphogenetic protein 2-like.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.972
LOC108264167	LOC108274296	ENSIPUP00000005898	ENSIPUP00000010986	Bone morphogenetic protein 2-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.973
LOC108264167	bmpr1a	ENSIPUP00000005898	ENSIPUP00000024163	Bone morphogenetic protein 2-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.973
LOC108264167	bmpr1b	ENSIPUP00000005898	ENSIPUP00000006921	Bone morphogenetic protein 2-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.973
LOC108264167	bmpr2	ENSIPUP00000005898	ENSIPUP00000018349	Bone morphogenetic protein 2-like.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.972
LOC108264167	runx1	ENSIPUP00000005898	ENSIPUP00000010539	Bone morphogenetic protein 2-like.	Runt-related transcription factor.	0.415
LOC108264167	runx2	ENSIPUP00000005898	ENSIPUP00000006243	Bone morphogenetic protein 2-like.	Runt-related transcription factor.	0.451
LOC108264167	runx3	ENSIPUP00000005898	ENSIPUP00000029359	Bone morphogenetic protein 2-like.	Runt-related transcription factor.	0.415
LOC108265003	ENSIPUP00000021843	ENSIPUP00000037241	ENSIPUP00000021843	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2 like.	0.577
LOC108265003	wnt5a	ENSIPUP00000037241	ENSIPUP00000036586	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Wingless-type MMTV integration site family, member 5.	0.616