38 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108259510	CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (436 aa)
	LOC108267538	Bcl2-associated agonist of cell death-like. (145 aa)
	LOC108279085	Diablo homolog, mitochondrial-like. (232 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1075 aa)
	LOC108278050	Caspase-8-like; Belongs to the peptidase C14A family. (362 aa)
	LOC108278075	Uncharacterized protein LOC108278075 isoform X2. (196 aa)
	nkx3-1	Homeobox protein Nkx-3.1. (215 aa)
	casp2	LOW QUALITY PROTEIN: caspase-2; Belongs to the peptidase C14A family. (439 aa)
	pidd1	P53-induced death domain-containing protein 1. (988 aa)
	LOC108280869	Mitochondrial ubiquitin ligase activator of nfkb 1-A-like. (339 aa)
	casp8ap2	CASP8-associated protein 2. (1894 aa)
	CRADD	Death domain-containing protein CRADD. (135 aa)
	p2rx1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (408 aa)
	cflar	CASP8 and FADD-like apoptosis regulator isoform X2; Belongs to the peptidase C14A family. (455 aa)
	f3	Tissue factor. (293 aa)
	faslg	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (260 aa)
	LOC108273098	Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (493 aa)
	LOC100304635	Caspase 8 isoform X1; Belongs to the peptidase C14A family. (371 aa)
	LOC108270970	Apoptosis regulator BAX-like. (202 aa)
	dap	Death-associated protein 1. (235 aa)
	BAX	BCL2 associated X, apoptosis regulator. (176 aa)
	bax	Apoptosis regulator BAX. (189 aa)
	hip1	Huntingtin-interacting protein 1 isoform X1. (1048 aa)
	LOC108280419	Tissue factor-like. (250 aa)
	LOC108260615	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (285 aa)
	LOC108274750	Apoptosis regulator BAX-like. (199 aa)
	ENSIPUP00000025403	annotation not available (128 aa)
	LOC108278350	Diablo homolog, mitochondrial-like. (265 aa)
	aifm1	LOW QUALITY PROTEIN: apoptosis-inducing factor 1, mitochondrial. (678 aa)
	LOC108266930	Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (525 aa)
	casp9	Caspase-9 isoform X2; Belongs to the peptidase C14A family. (432 aa)
	acer2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (274 aa)
	LOC108256952	Lysosomal-associated transmembrane protein 4A-like. (211 aa)
	pdcd2	Programmed Cell death protein 2. (337 aa)
	LOC108255864	Huntingtin-interacting protein 1-related protein-like isoform X1. (1064 aa)
	mul1	Mitochondrial ubiquitin ligase activator of NFKB 1. (348 aa)
	ctsh	Pro-cathepsin H precursor; Belongs to the peptidase C1 family. (326 aa)
	ngfr	Tumor necrosis factor receptor superfamily member 16 isoform X1. (378 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	LOC108267538	ENSIPUP00000022885	ENSIPUP00000005821	BCL2 associated X, apoptosis regulator.	Bcl2-associated agonist of cell death-like.	0.696
BAX	LOC108270970	ENSIPUP00000022885	ENSIPUP00000021392	BCL2 associated X, apoptosis regulator.	Apoptosis regulator BAX-like.	0.656
BAX	LOC108278350	ENSIPUP00000022885	ENSIPUP00000026051	BCL2 associated X, apoptosis regulator.	Diablo homolog, mitochondrial-like.	0.515
BAX	LOC108279085	ENSIPUP00000022885	ENSIPUP00000007968	BCL2 associated X, apoptosis regulator.	Diablo homolog, mitochondrial-like.	0.515
CRADD	casp2	ENSIPUP00000015391	ENSIPUP00000012697	Death domain-containing protein CRADD.	LOW QUALITY PROTEIN: caspase-2; Belongs to the peptidase C14A family.	0.961
CRADD	casp9	ENSIPUP00000015391	ENSIPUP00000028681	Death domain-containing protein CRADD.	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	0.545
CRADD	pidd1	ENSIPUP00000015391	ENSIPUP00000013200	Death domain-containing protein CRADD.	P53-induced death domain-containing protein 1.	0.984
ENSIPUP00000025403	LOC108267538	ENSIPUP00000025403	ENSIPUP00000005821	annotation not available	Bcl2-associated agonist of cell death-like.	0.696
ENSIPUP00000025403	LOC108270970	ENSIPUP00000025403	ENSIPUP00000021392	annotation not available	Apoptosis regulator BAX-like.	0.639
ENSIPUP00000025403	LOC108278350	ENSIPUP00000025403	ENSIPUP00000026051	annotation not available	Diablo homolog, mitochondrial-like.	0.515
ENSIPUP00000025403	LOC108279085	ENSIPUP00000025403	ENSIPUP00000007968	annotation not available	Diablo homolog, mitochondrial-like.	0.515
LOC100304635	LOC108259510	ENSIPUP00000020451	ENSIPUP00000004337	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family.	0.977
LOC100304635	LOC108278350	ENSIPUP00000020451	ENSIPUP00000026051	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Diablo homolog, mitochondrial-like.	0.404
LOC100304635	LOC108279085	ENSIPUP00000020451	ENSIPUP00000007968	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Diablo homolog, mitochondrial-like.	0.404
LOC100304635	casp2	ENSIPUP00000020451	ENSIPUP00000012697	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	LOW QUALITY PROTEIN: caspase-2; Belongs to the peptidase C14A family.	0.424
LOC100304635	casp9	ENSIPUP00000020451	ENSIPUP00000028681	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	0.536
LOC100304635	cflar	ENSIPUP00000020451	ENSIPUP00000016001	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	CASP8 and FADD-like apoptosis regulator isoform X2; Belongs to the peptidase C14A family.	0.815
LOC100304635	faslg	ENSIPUP00000020451	ENSIPUP00000017987	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family.	0.850
LOC108259510	LOC100304635	ENSIPUP00000004337	ENSIPUP00000020451	CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family.	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	0.977
LOC108259510	LOC108266930	ENSIPUP00000004337	ENSIPUP00000028592	CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family.	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	0.988