48 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ercc6	DNA excision repair protein ERCC-6. (1409 aa)
	LOC108273944	Histone acetyltransferase p300-like isoform X6. (2631 aa)
	e2f1	Transcription factor E2F1. (433 aa)
	LOC108260744	Folliculin-interacting protein 2-like. (841 aa)
	snw1	SNW domain-containing protein 1. (536 aa)
	LOC108255052	Tumor necrosis factor receptor superfamily member 1B-like. (418 aa)
	LOC108267538	Bcl2-associated agonist of cell death-like. (145 aa)
	prkdc	DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4101 aa)
	LOC108268142	Induced myeloid leukemia cell differentiation protein Mcl-1-like. (253 aa)
	tnfrsf1a	Tumor necrosis factor receptor superfamily member 1A. (402 aa)
	atm	Non-specific serine/threonine protein kinase. (3076 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (938 aa)
	casp2	LOW QUALITY PROTEIN: caspase-2; Belongs to the peptidase C14A family. (439 aa)
	tp63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (572 aa)
	shisa5	Protein shisa-5. (237 aa)
	cdip1	Cell death-inducing p53-target protein 1 isoform X1. (205 aa)
	brca2	Breast cancer type 2 susceptibility protein isoform X1. (2673 aa)
	bok	Bcl-2-related ovarian killer protein. (214 aa)
	bcl2l1	Bcl-2-like protein 1. (242 aa)
	bag6	Large proline-rich protein BAG6 isoform X1. (1196 aa)
	LOC108262800	Uncharacterized protein LOC108262800. (218 aa)
	LOC108267442	Ski-like protein isoform X1. (744 aa)
	mlh1	DNA mismatch repair protein Mlh1. (720 aa)
	LOC108270970	Apoptosis regulator BAX-like. (202 aa)
	nfatc4	Nuclear factor of activated T-cells, cytoplasmic 4. (643 aa)
	BAX	BCL2 associated X, apoptosis regulator. (176 aa)
	bax	Apoptosis regulator BAX. (189 aa)
	chek2	Serine/threonine-protein kinase Chk2. (539 aa)
	atad5	ATPase family AAA domain-containing protein 5 isoform X1. (1798 aa)
	LOC108264502	Anti-apoptotic protein NR13-like. (178 aa)
	LOC108274750	Apoptosis regulator BAX-like. (199 aa)
	LOC108256440	Ski-like protein. (675 aa)
	ENSIPUP00000025403	annotation not available (128 aa)
	LOC108278148	Bcl-2-related ovarian killer protein homolog B-like. (197 aa)
	bcl2l11	Bcl-2-like protein 11 isoform X2. (221 aa)
	sirt1	NAD-dependent protein deacetylase sirtuin-1 isoform X3. (731 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1428 aa)
	LOC108268551	Anti-apoptotic protein NR13-like. (178 aa)
	casp9	Caspase-9 isoform X2; Belongs to the peptidase C14A family. (432 aa)
	LOC108257145	Cell death-inducing p53-target protein 1-like isoform X2. (201 aa)
	usp47	Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1337 aa)
	tp73	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (586 aa)
	brca1	Breast cancer type 1 susceptibility protein isoform X2. (1369 aa)
	LOC108274846	Induced myeloid leukemia cell differentiation protein Mcl-1-like. (258 aa)
	LOC108273255	ATPase family AAA domain-containing protein 5-like. (927 aa)
	LOC108272975	Histone acetyltransferase p300-like isoform X2. (2494 aa)
	ier3	Radiation-inducible immediate-early gene IEX-1. (130 aa)
	LOC108277959	Large proline-rich protein BAG6-like isoform X1. (1305 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	LOC108267538	ENSIPUP00000022885	ENSIPUP00000005821	BCL2 associated X, apoptosis regulator.	Bcl2-associated agonist of cell death-like.	0.696
BAX	LOC108270970	ENSIPUP00000022885	ENSIPUP00000021392	BCL2 associated X, apoptosis regulator.	Apoptosis regulator BAX-like.	0.656
BAX	bcl2l1	ENSIPUP00000022885	ENSIPUP00000020079	BCL2 associated X, apoptosis regulator.	Bcl-2-like protein 1.	0.456
BAX	bcl2l11	ENSIPUP00000022885	ENSIPUP00000027147	BCL2 associated X, apoptosis regulator.	Bcl-2-like protein 11 isoform X2.	0.871
ENSIPUP00000025403	LOC108267538	ENSIPUP00000025403	ENSIPUP00000005821	annotation not available	Bcl2-associated agonist of cell death-like.	0.696
ENSIPUP00000025403	LOC108270970	ENSIPUP00000025403	ENSIPUP00000021392	annotation not available	Apoptosis regulator BAX-like.	0.639
ENSIPUP00000025403	bcl2l1	ENSIPUP00000025403	ENSIPUP00000020079	annotation not available	Bcl-2-like protein 1.	0.481
ENSIPUP00000025403	bcl2l11	ENSIPUP00000025403	ENSIPUP00000027147	annotation not available	Bcl-2-like protein 11 isoform X2.	0.871
LOC108255052	tnfrsf1a	ENSIPUP00000005601	ENSIPUP00000011585	Tumor necrosis factor receptor superfamily member 1B-like.	Tumor necrosis factor receptor superfamily member 1A.	0.714
LOC108264502	LOC108267538	ENSIPUP00000024401	ENSIPUP00000005821	Anti-apoptotic protein NR13-like.	Bcl2-associated agonist of cell death-like.	0.802
LOC108264502	bcl2l1	ENSIPUP00000024401	ENSIPUP00000020079	Anti-apoptotic protein NR13-like.	Bcl-2-like protein 1.	0.434
LOC108264502	bcl2l11	ENSIPUP00000024401	ENSIPUP00000027147	Anti-apoptotic protein NR13-like.	Bcl-2-like protein 11 isoform X2.	0.878
LOC108264502	tnfrsf1a	ENSIPUP00000024401	ENSIPUP00000011585	Anti-apoptotic protein NR13-like.	Tumor necrosis factor receptor superfamily member 1A.	0.469
LOC108267538	BAX	ENSIPUP00000005821	ENSIPUP00000022885	Bcl2-associated agonist of cell death-like.	BCL2 associated X, apoptosis regulator.	0.696
LOC108267538	ENSIPUP00000025403	ENSIPUP00000005821	ENSIPUP00000025403	Bcl2-associated agonist of cell death-like.	annotation not available	0.696
LOC108267538	LOC108264502	ENSIPUP00000005821	ENSIPUP00000024401	Bcl2-associated agonist of cell death-like.	Anti-apoptotic protein NR13-like.	0.802
LOC108267538	LOC108268142	ENSIPUP00000005821	ENSIPUP00000010331	Bcl2-associated agonist of cell death-like.	Induced myeloid leukemia cell differentiation protein Mcl-1-like.	0.683
LOC108267538	LOC108268551	ENSIPUP00000005821	ENSIPUP00000027965	Bcl2-associated agonist of cell death-like.	Anti-apoptotic protein NR13-like.	0.802
LOC108267538	LOC108270970	ENSIPUP00000005821	ENSIPUP00000021392	Bcl2-associated agonist of cell death-like.	Apoptosis regulator BAX-like.	0.787
LOC108267538	LOC108274750	ENSIPUP00000005821	ENSIPUP00000025129	Bcl2-associated agonist of cell death-like.	Apoptosis regulator BAX-like.	0.696