STRINGSTRING
mdk mdk LOC108279384 LOC108279384 LOC108277119 LOC108277119 LOC108274807 LOC108274807 LOC108264167 LOC108264167 LOC108267606 LOC108267606 smad4 smad4 bmp4 bmp4 LOC108260308 LOC108260308 LOC108280750 LOC108280750 lef1 lef1 lrg1 lrg1 LOC108274967 LOC108274967 LOC108280666 LOC108280666 LOC108274338 LOC108274338 dab2 dab2 il1b il1b ENSIPUP00000020164 ENSIPUP00000020164 il1b-2 il1b-2 tgfb2 tgfb2 tgfbr2 tgfbr2 alx1 alx1 LOC108273360 LOC108273360 glipr2 glipr2 mtor mtor LOC108255679 LOC108255679 rgcc rgcc LOC108268908 LOC108268908 LOC108255640 LOC108255640 loxl2 loxl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mdkMidkine. (146 aa)
LOC108279384Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
LOC108277119Zinc finger protein 703-like. (586 aa)
LOC108274807Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
LOC108264167Bone morphogenetic protein 2-like. (420 aa)
LOC108267606Mothers against decapentaplegic homolog. (574 aa)
smad4Mothers against decapentaplegic homolog. (546 aa)
bmp4Bone morphogenetic protein 4. (402 aa)
LOC108260308Disabled homolog 2-like isoform X2. (602 aa)
LOC108280750Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
lef1Lymphoid enhancer-binding factor 1 isoform X1. (362 aa)
lrg1Leucine-rich alpha-2-glycoprotein isoform X6. (327 aa)
LOC108274967midkine-B-like. (144 aa)
LOC108280666BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
LOC108274338BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
dab2Disabled homolog 2 isoform X1. (716 aa)
il1bInterleukin-1. (280 aa)
ENSIPUP00000020164annotation not available (180 aa)
il1b-2Interleukin-1. (280 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (572 aa)
alx1ALX homeobox protein 1 isoform X1. (328 aa)
LOC108273360Mothers against decapentaplegic homolog. (561 aa)
glipr2Golgi-associated plant pathogenesis-related protein 1; Belongs to the CRISP family. (154 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2525 aa)
LOC108255679Lysyl oxidase homolog 2B. (766 aa)
rgccRegulator of cell cycle RGCC. (156 aa)
LOC108268908Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LOC108255640Mothers against decapentaplegic homolog. (523 aa)
loxl2Lysyl oxidase homolog 2. (741 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.