STRINGSTRING
LOC108262421 LOC108262421 LOC108266640 LOC108266640 nodal nodal gdf6 gdf6 gdf5 gdf5 LOC108269656 LOC108269656 LOC108279384 LOC108279384 inhba inhba LOC108267203 LOC108267203 LOC108274807 LOC108274807 LOC108264167 LOC108264167 LOC108267606 LOC108267606 gdf3 gdf3 inha inha LOC108279289 LOC108279289 smad4 smad4 LOC108276621 LOC108276621 acvr1 acvr1 bmp4 bmp4 LOC108260308 LOC108260308 LOC108280750 LOC108280750 LOC108257744 LOC108257744 LOC108267867 LOC108267867 mstn mstn LOC108275854 LOC108275854 LOC108259508 LOC108259508 LOC108280221 LOC108280221 bmp3 bmp3 LOC108266333 LOC108266333 dab2 dab2 bmpr2 bmpr2 LOC108254821 LOC108254821 gdf10 gdf10 LOC108273396 LOC108273396 bmp5 bmp5 LOC108255743 LOC108255743 tgfb2 tgfb2 tgfbr2 tgfbr2 LOC108256196 LOC108256196 LOC108273360 LOC108273360 LOC108255530 LOC108255530 INHBB INHBB LOC108270114 LOC108270114 LOC108272897 LOC108272897 bmp8a bmp8a LOC108268908 LOC108268908 LOC108255640 LOC108255640 inhbb inhbb bmp7 bmp7 INHBC INHBC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108262421Growth/differentiation factor 10-like. (439 aa)
LOC108266640Inhibin beta A chain-like. (397 aa)
nodalNodal homolog. (405 aa)
gdf6Growth/differentiation factor 6. (402 aa)
gdf5Growth/differentiation factor 5. (435 aa)
LOC108269656Left-right determination factor 1-like. (351 aa)
LOC108279384Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
inhbaInhibin beta A chain. (413 aa)
LOC108267203Bone morphogenetic protein 15-like. (439 aa)
LOC108274807Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
LOC108264167Bone morphogenetic protein 2-like. (420 aa)
LOC108267606Mothers against decapentaplegic homolog. (574 aa)
gdf3Growth/differentiation factor 3 isoform X1. (363 aa)
inhaInhibin alpha chain isoform X3. (356 aa)
LOC108279289Nodal homolog 2-A-like. (375 aa)
smad4Mothers against decapentaplegic homolog. (546 aa)
LOC108276621Bone morphogenetic protein 10-like isoform X1. (448 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (723 aa)
bmp4Bone morphogenetic protein 4. (402 aa)
LOC108260308Disabled homolog 2-like isoform X2. (602 aa)
LOC108280750Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
LOC108257744Left-right determination factor. (358 aa)
LOC108267867Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (526 aa)
mstnGrowth/differentiation factor 8. (390 aa)
LOC108275854Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
LOC108259508Growth/differentiation factor 8-like. (442 aa)
LOC108280221Derriere protein-like. (357 aa)
bmp3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (446 aa)
LOC108266333Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (581 aa)
dab2Disabled homolog 2 isoform X1. (716 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1058 aa)
LOC108254821Growth/differentiation factor 11-like isoform X1. (417 aa)
gdf10Growth/differentiation factor 10. (419 aa)
LOC108273396Growth/differentiation factor 2-like. (402 aa)
bmp5Bone morphogenetic protein 5. (452 aa)
LOC108255743Bone morphogenetic protein 10-like. (472 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (572 aa)
LOC108256196Growth/differentiation factor 6-A-like. (413 aa)
LOC108273360Mothers against decapentaplegic homolog. (561 aa)
LOC108255530Nodal homolog. (392 aa)
INHBBInhibin beta B chain-like. (388 aa)
LOC108270114Growth/differentiation factor 6-A-like. (407 aa)
LOC108272897Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
bmp8aBone morphogenetic protein 8A. (459 aa)
LOC108268908Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LOC108255640Mothers against decapentaplegic homolog. (523 aa)
inhbbInhibin beta B chain. (383 aa)
bmp7Bone morphogenetic protein 7. (425 aa)
INHBCInhibin beta B chain-like. (389 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.