STRINGSTRING
LOC108276435 LOC108276435 fgf2 fgf2 spry1 spry1 LOC108265141 LOC108265141 fzd8 fzd8 LOC108262840 LOC108262840 LOC108255556 LOC108255556 ern2 ern2 fzd4 fzd4 dusp10 dusp10 aida aida LOC108260470 LOC108260470 LOC108279384 LOC108279384 nox4 nox4 pdcd10 pdcd10 ENSIPUP00000004727 ENSIPUP00000004727 LOC108270447 LOC108270447 pdgfc pdgfc pik3r5 pik3r5 smpd1 smpd1 nf1 nf1 LOC108264167 LOC108264167 LOC108274787 LOC108274787 LOC108269670 LOC108269670 ENSIPUP00000006440 ENSIPUP00000006440 LOC108275773 LOC108275773 sash1 sash1 dusp19 dusp19 map3k4 map3k4 tnc tnc tsg101 tsg101 bmp4 bmp4 ajuba ajuba LOC108280750 LOC108280750 map3k13 map3k13 LOC108279299 LOC108279299 hgs hgs tgfb3 tgfb3 LOC108265400 LOC108265400 gba gba LOC108274431 LOC108274431 drd4 drd4 paqr3 paqr3 LOC108259026 LOC108259026 fgf1 fgf1 dkk1 dkk1 kit kit LOC108259423 LOC108259423 map3k7 map3k7 LOC108270559 LOC108270559 ern1 ern1 fgf1-2 fgf1-2 spry4 spry4 LOC108265732 LOC108265732 ENSIPUP00000017435 ENSIPUP00000017435 LOC108259440 LOC108259440 edn1 edn1 sorl1 sorl1 ENSIPUP00000018803 ENSIPUP00000018803 LOC108272952 LOC108272952 tnfrsf11a tnfrsf11a il1b il1b ENSIPUP00000020164 ENSIPUP00000020164 il1b-2 il1b-2 LOC108269231 LOC108269231 tenm1 tenm1 pdc10 pdc10 LOC108278928 LOC108278928 ENSIPUP00000021843 ENSIPUP00000021843 agt agt pik3cg pik3cg irak3 irak3 LOC108272579 LOC108272579 LOC108271731 LOC108271731 cdk5rap3 cdk5rap3 hmgcr hmgcr cav3 cav3 axin1 axin1 trib2 trib2 LOC108276426 LOC108276426 map2k5 map2k5 ptprc ptprc LOC108268090 LOC108268090 LOC108268415 LOC108268415 il34 il34 LOC108255518 LOC108255518 LOC108278595 LOC108278595 map2k7 map2k7 LOC108276969 LOC108276969 LOC108276876 LOC108276876 tnfsf11 tnfsf11 ts101 ts101 LOC108259581 LOC108259581 ENSIPUP00000033462 ENSIPUP00000033462 lrrk2 lrrk2 nek10 nek10 fzd5 fzd5 htr2b htr2b LOC108254833 LOC108254833
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108276435Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like; Belongs to the PI3/PI4-kinase family. (1099 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (151 aa)
spry1Protein sprouty homolog 1. (294 aa)
LOC108265141Basic salivary proline-rich protein 2-like isoform X1. (122 aa)
fzd8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
LOC108262840Dickkopf-related protein 1-like. (282 aa)
LOC108255556SH2B adapter protein 3-like. (346 aa)
ern2Serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1. (929 aa)
fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
dusp10Dual specificity protein phosphatase 10 isoform X1. (461 aa)
aidaAxin interactor, dorsalization-associated protein isoform X1. (303 aa)
LOC108260470RNA polymerase II degradation factor 1-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (581 aa)
LOC108279384Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
nox4NADPH oxidase 4 isoform X1. (539 aa)
pdcd10Programmed Cell death protein 10. (210 aa)
ENSIPUP00000004727annotation not available (151 aa)
LOC108270447SAM and SH3 domain-containing protein 1-like isoform X1. (1027 aa)
pdgfcPlatelet-derived growth factor C isoform X1. (375 aa)
pik3r5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (883 aa)
smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (598 aa)
nf1Neurofibromin isoform X5. (2745 aa)
LOC108264167Bone morphogenetic protein 2-like. (420 aa)
LOC108274787Uncharacterized protein LOC108274787. (1735 aa)
LOC108269670Tribbles homolog 2-like. (289 aa)
ENSIPUP00000006440annotation not available (274 aa)
LOC108275773Uncharacterized protein LOC108275773. (443 aa)
sash1SAM and SH3 domain-containing protein 1 isoform X2. (1171 aa)
dusp19Dual specificity protein phosphatase 19. (214 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4 isoform X2. (1528 aa)
tncTenascin isoform X1. (2220 aa)
tsg101Tumor susceptibility gene 101 protein isoform X1. (390 aa)
bmp4Bone morphogenetic protein 4. (402 aa)
ajubaLIM domain-containing protein ajuba. (714 aa)
LOC108280750Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
map3k13Mitogen-activated protein kinase kinase kinase. (953 aa)
LOC108279299Protein sprouty homolog 2-like. (283 aa)
hgsHepatocyte growth factor-regulated tyrosine kinase substrate isoform X5. (766 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC108265400Fibroblast growth factor receptor. (827 aa)
gbaGlucosylceramidase. (531 aa)
LOC108274431Fibroblast growth factor 18-like isoform X1; Belongs to the heparin-binding growth factors family. (208 aa)
drd4D(4) dopamine receptor. (384 aa)
paqr3Progestin and adipoQ receptor family member 3 isoform X1. (312 aa)
LOC108259026Protein sprouty homolog 2-like. (333 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
dkk1Dickkopf-related protein 1. (236 aa)
kitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
LOC108259423Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (476 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (550 aa)
LOC108270559D(4) dopamine receptor-like; Belongs to the G-protein coupled receptor 1 family. (402 aa)
ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (1038 aa)
fgf1-2Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
spry4Protein sprouty homolog 4. (312 aa)
LOC108265732Fibroblast growth factor receptor 1-A-like. (260 aa)
ENSIPUP00000017435Fibroblast growth factor receptor 1-A-like. (285 aa)
LOC108259440Platelet-derived growth factor subunit A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (203 aa)
edn1Endothelin-1. (195 aa)
sorl1Sortilin-related receptor isoform X1. (2208 aa)
ENSIPUP00000018803annotation not available (129 aa)
LOC108272952Tribbles homolog 1-like. (350 aa)
tnfrsf11aTumor necrosis factor receptor superfamily member 11A isoform X1. (572 aa)
il1bInterleukin-1. (280 aa)
ENSIPUP00000020164annotation not available (180 aa)
il1b-2Interleukin-1. (280 aa)
LOC108269231Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
tenm1Teneurin-1. (2638 aa)
pdc10Programmed cell death protein 10 isoform X1. (210 aa)
LOC1082789283-hydroxy-3-methylglutaryl coenzyme A reductase. (858 aa)
ENSIPUP00000021843Secreted frizzled-related protein 2 like. (231 aa)
agtAngiotensinogen; Belongs to the serpin family. (451 aa)
pik3cgPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1105 aa)
irak3Interleukin-1 receptor-associated kinase 3. (609 aa)
LOC108272579Dysbindin-like isoform X1. (188 aa)
LOC108271731Protransforming growth factor alpha-like isoform X1. (196 aa)
cdk5rap3CDK5 regulatory subunit-associated protein 3. (504 aa)
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (886 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
axin1Axin-1 isoform X1. (806 aa)
trib2Tribbles homolog 2 isoform X1. (346 aa)
LOC108276426Tumor necrosis factor receptor superfamily member 5-like. (310 aa)
map2k5Dual specificity mitogen-activated protein kinase kinase 5 isoform X4; Belongs to the protein kinase superfamily. (449 aa)
ptprcReceptor-type tyrosine-protein phosphatase C precursor. (1165 aa)
LOC108268090Serine/threonine-protein kinase ppk4-like. (408 aa)
LOC108268415Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
il34Interleukin-34. (211 aa)
LOC108255518C-C motif chemokine 19-like isoform X1. (115 aa)
LOC108278595Uncharacterized protein LOC108278567. (879 aa)
map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (445 aa)
LOC108276969Neurofibromin isoform X3. (2756 aa)
LOC108276876Progestin and adipoQ receptor family member 3-like. (308 aa)
tnfsf11Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (255 aa)
ts101Tumor susceptibility gene 101 protein. (389 aa)
LOC108259581Uncharacterized protein LOC108259581. (357 aa)
ENSIPUP00000033462annotation not available (73 aa)
lrrk2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2455 aa)
nek10Serine/threonine-protein kinase Nek10 isoform X1. (1058 aa)
fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
htr2b5-hydroxytryptamine receptor 2B. (445 aa)
LOC108254833Tribbles homolog 2-like. (348 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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