20 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ddit3	DNA damage-inducible transcript 3 protein. (273 aa)
	ENSIPUP00000025403	annotation not available (128 aa)
	nf1	Neurofibromin isoform X5. (2745 aa)
	LOC108274195	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1; Belongs to the protein kinase superfamily. (425 aa)
	atm	Non-specific serine/threonine protein kinase. (3076 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (651 aa)
	nfatc4	Nuclear factor of activated T-cells, cytoplasmic 4. (643 aa)
	BAX	BCL2 associated X, apoptosis regulator. (176 aa)
	bax	Apoptosis regulator BAX. (189 aa)
	LOC108274750	Apoptosis regulator BAX-like. (199 aa)
	cdk5	Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
	bcl2l11	Bcl-2-like protein 11 isoform X2. (221 aa)
	aifm1	LOW QUALITY PROTEIN: apoptosis-inducing factor 1, mitochondrial. (678 aa)
	casp9	Caspase-9 isoform X2; Belongs to the peptidase C14A family. (432 aa)
	map2k7	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (445 aa)
	LOC108276969	Neurofibromin isoform X3. (2756 aa)
	map2k4	Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily. (420 aa)
	LOC108268908	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	rapsn	43 kDa receptor-associated protein of the synapse. (419 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	bcl2l11	ENSIPUP00000022885	ENSIPUP00000027147	BCL2 associated X, apoptosis regulator.	Bcl-2-like protein 11 isoform X2.	0.871
ENSIPUP00000025403	bcl2l11	ENSIPUP00000025403	ENSIPUP00000027147	annotation not available	Bcl-2-like protein 11 isoform X2.	0.871
LOC108268908	tgfb2	ENSIPUP00000033493	ENSIPUP00000025520	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.901
LOC108274195	map2k4	ENSIPUP00000007411	ENSIPUP00000033218	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1; Belongs to the protein kinase superfamily.	Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily.	0.901
LOC108274195	map2k7	ENSIPUP00000007411	ENSIPUP00000031342	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1; Belongs to the protein kinase superfamily.	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	0.973
LOC108274750	bcl2l11	ENSIPUP00000025129	ENSIPUP00000027147	Apoptosis regulator BAX-like.	Bcl-2-like protein 11 isoform X2.	0.986
LOC108276969	atm	ENSIPUP00000031599	ENSIPUP00000012238	Neurofibromin isoform X3.	Non-specific serine/threonine protein kinase.	0.418
aifm1	casp9	ENSIPUP00000027239	ENSIPUP00000028681	LOW QUALITY PROTEIN: apoptosis-inducing factor 1, mitochondrial.	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	0.584
atm	LOC108276969	ENSIPUP00000012238	ENSIPUP00000031599	Non-specific serine/threonine protein kinase.	Neurofibromin isoform X3.	0.418
atm	nf1	ENSIPUP00000012238	ENSIPUP00000005123	Non-specific serine/threonine protein kinase.	Neurofibromin isoform X5.	0.418
bax	bcl2l11	ENSIPUP00000022942	ENSIPUP00000027147	Apoptosis regulator BAX.	Bcl-2-like protein 11 isoform X2.	0.990
bax	casp9	ENSIPUP00000022942	ENSIPUP00000028681	Apoptosis regulator BAX.	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	0.496
bcl2l11	BAX	ENSIPUP00000027147	ENSIPUP00000022885	Bcl-2-like protein 11 isoform X2.	BCL2 associated X, apoptosis regulator.	0.871
bcl2l11	ENSIPUP00000025403	ENSIPUP00000027147	ENSIPUP00000025403	Bcl-2-like protein 11 isoform X2.	annotation not available	0.871
bcl2l11	LOC108274750	ENSIPUP00000027147	ENSIPUP00000025129	Bcl-2-like protein 11 isoform X2.	Apoptosis regulator BAX-like.	0.986
bcl2l11	bax	ENSIPUP00000027147	ENSIPUP00000022942	Bcl-2-like protein 11 isoform X2.	Apoptosis regulator BAX.	0.990
bcl2l11	casp9	ENSIPUP00000027147	ENSIPUP00000028681	Bcl-2-like protein 11 isoform X2.	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	0.559
bcl2l11	ddit3	ENSIPUP00000027147	ENSIPUP00000036454	Bcl-2-like protein 11 isoform X2.	DNA damage-inducible transcript 3 protein.	0.560
casp9	aifm1	ENSIPUP00000028681	ENSIPUP00000027239	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	LOW QUALITY PROTEIN: apoptosis-inducing factor 1, mitochondrial.	0.584
casp9	bax	ENSIPUP00000028681	ENSIPUP00000022942	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	Apoptosis regulator BAX.	0.496