(27 nodes) Late endosome to vacuole transport network (Ictalurus punctatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	snf8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	chm4c	Charged multivesicular body protein 4C. (236 aa)
	stam	Signal transducing adapter molecule 1. (507 aa)
	vps36	Vacuolar protein-sorting-associated protein 36. (381 aa)
	LOC108277388	Charged multivesicular body protein 6-like isoform X2. (204 aa)
	chmp5	Charged multivesicular body protein 5 isoform X1. (219 aa)
	LOC108272732	Charged multivesicular body protein 4b. (222 aa)
	vta1	Vacuolar protein sorting-associated protein vta1-like protein. (306 aa)
	LOC108266599	Transmembrane protein 50B-like isoform X1. (158 aa)
	chmp6	Charged multivesicular body protein 6. (204 aa)
	chmp1a	Charged multivesicular body protein 1A. (198 aa)
	chmp7	Charged multivesicular body protein 7. (443 aa)
	ptpn23	Tyrosine-protein phosphatase non-receptor type 23 isoform X3. (1959 aa)
	LOC108257436	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1. (1212 aa)
	LOC108265407	Charged multivesicular body protein 4b. (221 aa)
	leprot	Leptin receptor gene-related protein. (173 aa)
	vps25	Vacuolar protein-sorting-associated protein 25. (174 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (223 aa)
	chmp5-2	Charged multivesicular body protein 5. (220 aa)
	chmp2a	Charged multivesicular body protein 2A. (222 aa)
	tmem50a	Transmembrane protein 50A isoform X1. (191 aa)
	pik3r4	Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1381 aa)
	becn1	Beclin-1. (448 aa)
	chmp2b	Charged multivesicular body protein 2b. (214 aa)
	chm2b	Charged multivesicular body protein 2B. (216 aa)
	chmp3	Charged multivesicular body protein 3. (219 aa)
	leprotl1	Leptin receptor overlapping transcript-like 1. (131 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108257436	LOC108265407	ENSIPUP00000017433	ENSIPUP00000018880	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 4b.	0.886
LOC108257436	LOC108272732	ENSIPUP00000017433	ENSIPUP00000006232	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 4b.	0.886
LOC108257436	chm4c	ENSIPUP00000017433	ENSIPUP00000004752	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 4C.	0.886
LOC108257436	chmp1a	ENSIPUP00000017433	ENSIPUP00000010919	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 1A.	0.409
LOC108257436	chmp2a	ENSIPUP00000017433	ENSIPUP00000029034	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 2A.	0.432
LOC108257436	chmp3	ENSIPUP00000017433	ENSIPUP00000035676	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 3.	0.445
LOC108257436	chmp5	ENSIPUP00000017433	ENSIPUP00000006077	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 5 isoform X1.	0.539
LOC108257436	chmp5-2	ENSIPUP00000017433	ENSIPUP00000023855	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Charged multivesicular body protein 5.	0.539
LOC108257436	stam	ENSIPUP00000017433	ENSIPUP00000005192	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Signal transducing adapter molecule 1.	0.882
LOC108257436	vps25	ENSIPUP00000017433	ENSIPUP00000021119	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Vacuolar protein-sorting-associated protein 25.	0.411
LOC108257436	vps28	ENSIPUP00000017433	ENSIPUP00000021961	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.578
LOC108257436	vps36	ENSIPUP00000017433	ENSIPUP00000005406	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Vacuolar protein-sorting-associated protein 36.	0.422
LOC108257436	vta1	ENSIPUP00000017433	ENSIPUP00000006890	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	Vacuolar protein sorting-associated protein vta1-like protein.	0.434
LOC108265407	LOC108257436	ENSIPUP00000018880	ENSIPUP00000017433	Charged multivesicular body protein 4b.	Tyrosine-protein phosphatase non-receptor type 23-like isoform X1.	0.886
LOC108265407	LOC108272732	ENSIPUP00000018880	ENSIPUP00000006232	Charged multivesicular body protein 4b.	Charged multivesicular body protein 4b.	0.901
LOC108265407	LOC108277388	ENSIPUP00000018880	ENSIPUP00000005644	Charged multivesicular body protein 4b.	Charged multivesicular body protein 6-like isoform X2.	0.882
LOC108265407	chm2b	ENSIPUP00000018880	ENSIPUP00000034902	Charged multivesicular body protein 4b.	Charged multivesicular body protein 2B.	0.745
LOC108265407	chm4c	ENSIPUP00000018880	ENSIPUP00000004752	Charged multivesicular body protein 4b.	Charged multivesicular body protein 4C.	0.911
LOC108265407	chmp1a	ENSIPUP00000018880	ENSIPUP00000010919	Charged multivesicular body protein 4b.	Charged multivesicular body protein 1A.	0.875
LOC108265407	chmp2a	ENSIPUP00000018880	ENSIPUP00000029034	Charged multivesicular body protein 4b.	Charged multivesicular body protein 2A.	0.945