STRINGSTRING
ctnnbip1 ctnnbip1 LOC108264167 LOC108264167 LOC108267606 LOC108267606 gdnf gdnf LOC108274048 LOC108274048 smad4 smad4 bmp4 bmp4 LOC108273496 LOC108273496 npnt npnt fgf1 fgf1 LOC108263149 LOC108263149 wt1 wt1 wnt6 wnt6 tcf21 tcf21 fgf1-2 fgf1-2 nog nog ilk ilk LOC108264570 LOC108264570 LOC108271533 LOC108271533 greb1 greb1 tmem59l tmem59l LOC108277568 LOC108277568 LOC108273360 LOC108273360 LOC108255640 LOC108255640
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
LOC108264167Bone morphogenetic protein 2-like. (420 aa)
LOC108267606Mothers against decapentaplegic homolog. (574 aa)
gdnfGlial cell line-derived neurotrophic factor. (295 aa)
LOC108274048Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (659 aa)
smad4Mothers against decapentaplegic homolog. (546 aa)
bmp4Bone morphogenetic protein 4. (402 aa)
LOC108273496Epithelial cell adhesion molecule-like. (283 aa)
npntNephronectin isoform X1. (627 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC108263149Epithelial cell adhesion molecule-like. (309 aa)
wt1Wilms tumor protein isoform X1. (418 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
tcf21Transcription factor 21. (189 aa)
fgf1-2Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
nogNoggin; Belongs to the noggin family. (225 aa)
ilkIntegrin-linked protein kinase. (452 aa)
LOC108264570Wilms tumor protein homolog isoform X1. (397 aa)
LOC108271533Heparan sulfate 2-O-sulfotransferase 1. (356 aa)
greb1Protein GREB1. (1822 aa)
tmem59lTransmembrane protein 59-like. (173 aa)
LOC108277568Heparan sulfate 2-O-sulfotransferase 1-like. (349 aa)
LOC108273360Mothers against decapentaplegic homolog. (561 aa)
LOC108255640Mothers against decapentaplegic homolog. (523 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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