24 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tmem59l	Transmembrane protein 59-like. (173 aa)
	ctnnbip1	Beta-catenin-interacting protein 1. (81 aa)
	LOC108264167	Bone morphogenetic protein 2-like. (420 aa)
	LOC108267606	Mothers against decapentaplegic homolog. (574 aa)
	gdnf	Glial cell line-derived neurotrophic factor. (295 aa)
	LOC108274048	Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (659 aa)
	smad4	Mothers against decapentaplegic homolog. (546 aa)
	bmp4	Bone morphogenetic protein 4. (402 aa)
	LOC108273496	Epithelial cell adhesion molecule-like. (283 aa)
	npnt	Nephronectin isoform X1. (627 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	LOC108263149	Epithelial cell adhesion molecule-like. (309 aa)
	wt1	Wilms tumor protein isoform X1. (418 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	tcf21	Transcription factor 21. (189 aa)
	fgf1-2	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
	LOC108255640	Mothers against decapentaplegic homolog. (523 aa)
	LOC108273360	Mothers against decapentaplegic homolog. (561 aa)
	LOC108277568	Heparan sulfate 2-O-sulfotransferase 1-like. (349 aa)
	greb1	Protein GREB1. (1822 aa)
	LOC108271533	Heparan sulfate 2-O-sulfotransferase 1. (356 aa)
	LOC108264570	Wilms tumor protein homolog isoform X1. (397 aa)
	ilk	Integrin-linked protein kinase. (452 aa)
	nog	Noggin; Belongs to the noggin family. (225 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108255640	LOC108264167	ENSIPUP00000035179	ENSIPUP00000005898	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2-like.	0.639
LOC108255640	bmp4	ENSIPUP00000035179	ENSIPUP00000008975	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.695
LOC108264167	LOC108255640	ENSIPUP00000005898	ENSIPUP00000035179	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog.	0.639
LOC108264167	LOC108267606	ENSIPUP00000005898	ENSIPUP00000006258	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog.	0.639
LOC108264167	LOC108273360	ENSIPUP00000005898	ENSIPUP00000027339	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog.	0.639
LOC108264167	nog	ENSIPUP00000005898	ENSIPUP00000018088	Bone morphogenetic protein 2-like.	Noggin; Belongs to the noggin family.	0.797
LOC108264167	smad4	ENSIPUP00000005898	ENSIPUP00000007352	Bone morphogenetic protein 2-like.	Mothers against decapentaplegic homolog.	0.639
LOC108264570	tcf21	ENSIPUP00000019034	ENSIPUP00000015552	Wilms tumor protein homolog isoform X1.	Transcription factor 21.	0.464
LOC108267606	LOC108264167	ENSIPUP00000006258	ENSIPUP00000005898	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2-like.	0.639
LOC108267606	LOC108273360	ENSIPUP00000006258	ENSIPUP00000027339	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC108267606	bmp4	ENSIPUP00000006258	ENSIPUP00000008975	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.639
LOC108267606	smad4	ENSIPUP00000006258	ENSIPUP00000007352	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC108273360	LOC108264167	ENSIPUP00000027339	ENSIPUP00000005898	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2-like.	0.639
LOC108273360	LOC108267606	ENSIPUP00000027339	ENSIPUP00000006258	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
LOC108273360	bmp4	ENSIPUP00000027339	ENSIPUP00000008975	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.639
LOC108273360	smad4	ENSIPUP00000027339	ENSIPUP00000007352	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.901
bmp4	LOC108255640	ENSIPUP00000008975	ENSIPUP00000035179	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.695
bmp4	LOC108267606	ENSIPUP00000008975	ENSIPUP00000006258	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.639
bmp4	LOC108273360	ENSIPUP00000008975	ENSIPUP00000027339	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.639
bmp4	nog	ENSIPUP00000008975	ENSIPUP00000018088	Bone morphogenetic protein 4.	Noggin; Belongs to the noggin family.	0.797