STRINGSTRING
BTBD7 BTBD7 spry1 spry1 LOC108276021 LOC108276021 sox10 sox10 LOC108280865 LOC108280865 LOC108279384 LOC108279384 ENSIPUP00000005375 ENSIPUP00000005375 LOC108274807 LOC108274807 ctnnbip1 ctnnbip1 LOC108264167 LOC108264167 dlg5 dlg5 LOC108267606 LOC108267606 ednra ednra LOC108270435 LOC108270435 gdnf gdnf ENSIPUP00000006938 ENSIPUP00000006938 hhip hhip lrp6 lrp6 smad4 smad4 bmp4 bmp4 LOC108264812 LOC108264812 LOC108280750 LOC108280750 LOC108277494 LOC108277494 pkd1 pkd1 lrp5 lrp5 nkx3-1 nkx3-1 dag1 dag1 npnt npnt lef1 lef1 LOC108259026 LOC108259026 LOC108266333 LOC108266333 fgf1 fgf1 socs3 socs3 wt1 wt1 wnt6 wnt6 tcf21 tcf21 ctsz ctsz fgf1-2 fgf1-2 LOC108259890 LOC108259890 sox9 sox9 gbx2 gbx2 LOC108265008 LOC108265008 edn1 edn1 nog nog ilk ilk fem1b fem1b timeless timeless LOC108264570 LOC108264570 greb1 greb1 LOC108255347 LOC108255347 LOC108277309 LOC108277309 ENSIPUP00000021843 ENSIPUP00000021843 LOC108274104 LOC108274104 nfatc4 nfatc4 fgf7 fgf7 ar ar ENSIPUP00000024431 ENSIPUP00000024431 tmem59l tmem59l ppp3r1 ppp3r1 LOC108280169 LOC108280169 tgfbr2 tgfbr2 LOC108257674 LOC108257674 sars1 sars1 LOC108273360 LOC108273360 LOC108257833 LOC108257833 srf srf LOC108258023 LOC108258023 spint1 spint1 rspo2 rspo2 TMED2 TMED2 nrarp nrarp med1 med1 LOC108270114 LOC108270114 LOC108269268 LOC108269268 mks1 mks1 LOC108270922 LOC108270922 LOC108255640 LOC108255640 il10 il10 ctsh ctsh LOC108258530 LOC108258530 sema3c sema3c LOC108280990 LOC108280990 LOC108265115 LOC108265115
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BTBD7BTB/POZ domain-containing protein 7-like. (1108 aa)
spry1Protein sprouty homolog 1. (294 aa)
LOC108276021Endothelin B receptor-like; Belongs to the G-protein coupled receptor 1 family. (505 aa)
sox10Transcription factor SOX-10. (468 aa)
LOC108280865Vascular endothelial growth factor A-A-like; Belongs to the PDGF/VEGF growth factor family. (185 aa)
LOC108279384Transforming growth factor beta; Belongs to the TGF-beta family. (380 aa)
ENSIPUP00000005375Polycystic kidney disease 1b. (3029 aa)
LOC108274807Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
LOC108264167Bone morphogenetic protein 2-like. (420 aa)
dlg5Disks large homolog 5 isoform X5; Belongs to the MAGUK family. (1970 aa)
LOC108267606Mothers against decapentaplegic homolog. (574 aa)
ednraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (424 aa)
LOC108270435Bone morphogenetic protein 2-like. (392 aa)
gdnfGlial cell line-derived neurotrophic factor. (295 aa)
ENSIPUP00000006938Si:ch211-194g2.4. (144 aa)
hhipHedgehog-interacting protein isoform X2. (690 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
smad4Mothers against decapentaplegic homolog. (546 aa)
bmp4Bone morphogenetic protein 4. (402 aa)
LOC108264812Semaphorin-3ab; Belongs to the semaphorin family. (780 aa)
LOC108280750Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
LOC108277494Kunitz-type protease inhibitor 2-like. (406 aa)
pkd1Polycystin-1. (4383 aa)
lrp5Low-density lipoprotein receptor-related protein 5. (1534 aa)
nkx3-1Homeobox protein Nkx-3.1. (215 aa)
dag1Dystroglycan. (867 aa)
npntNephronectin isoform X1. (627 aa)
lef1Lymphoid enhancer-binding factor 1 isoform X1. (362 aa)
LOC108259026Protein sprouty homolog 2-like. (333 aa)
LOC108266333Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (581 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
socs3Suppressor of cytokine signaling 3. (201 aa)
wt1Wilms tumor protein isoform X1. (418 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
tcf21Transcription factor 21. (189 aa)
ctszCathepsin Z isoform X2; Belongs to the peptidase C1 family. (291 aa)
fgf1-2Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC108259890Transcription factor Sox-9-A-like. (464 aa)
sox9Transcription factor SOX-9. (449 aa)
gbx2Homeobox protein GBX-2. (332 aa)
LOC108265008Uncharacterized protein LOC108265008. (280 aa)
edn1Endothelin-1. (195 aa)
nogNoggin; Belongs to the noggin family. (225 aa)
ilkIntegrin-linked protein kinase. (452 aa)
fem1bProtein fem-1 homolog B. (627 aa)
timelessProtein timeless homolog. (1245 aa)
LOC108264570Wilms tumor protein homolog isoform X1. (397 aa)
greb1Protein GREB1. (1822 aa)
LOC108255347Notch-regulated ankyrin repeat-containing protein B. (111 aa)
LOC108277309Transmembrane emp24 domain-containing protein 2-like. (193 aa)
ENSIPUP00000021843Secreted frizzled-related protein 2 like. (231 aa)
LOC108274104Suppressor of cytokine signaling 3-like. (223 aa)
nfatc4Nuclear factor of activated T-cells, cytoplasmic 4. (643 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
arAndrogen receptor. (848 aa)
ENSIPUP00000024431annotation not available (289 aa)
tmem59lTransmembrane protein 59-like. (173 aa)
ppp3r1Calcineurin subunit B type 1. (170 aa)
LOC108280169Cathepsin Z-like; Belongs to the peptidase C1 family. (329 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (572 aa)
LOC108257674Kunitz-type protease inhibitor 1-like. (488 aa)
sars1Serine--tRNA ligase, cytoplasmic. (515 aa)
LOC108273360Mothers against decapentaplegic homolog. (561 aa)
LOC108257833BTB/POZ domain-containing protein 7-like. (1006 aa)
srfSerum response factor isoform X3. (599 aa)
LOC108258023Bone morphogenetic protein 2-like. (410 aa)
spint1Kunitz-type protease inhibitor 1 isoform X2. (514 aa)
rspo2R-spondin-2 isoform X1. (269 aa)
TMED2Transmembrane emp24 domain-containing protein 2. (208 aa)
nrarpNotch-regulated ankyrin repeat-containing protein. (112 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1778 aa)
LOC108270114Growth/differentiation factor 6-A-like. (407 aa)
LOC108269268Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (459 aa)
mks1Meckel syndrome type 1 protein. (557 aa)
LOC108270922Serum response factor-like isoform X1. (442 aa)
LOC108255640Mothers against decapentaplegic homolog. (523 aa)
il10Interleukin-10. (223 aa)
ctshPro-cathepsin H precursor; Belongs to the peptidase C1 family. (326 aa)
LOC108258530Calcineurin subunit B type 1. (170 aa)
sema3csemaphorin-3C; Belongs to the semaphorin family. (665 aa)
LOC108280990Uncharacterized protein LOC108280990. (199 aa)
LOC108265115Dystroglycan-like isoform X1. (862 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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