57 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	aida	Axin interactor, dorsalization-associated protein isoform X1. (303 aa)
	LOC108275286	cAMP-dependent protein kinase type II-beta regulatory subunit-like. (403 aa)
	LOC108259206	Cyclin-dependent kinase inhibitor 1B-like. (204 aa)
	LOC108276876	Progestin and adipoQ receptor family member 3-like. (308 aa)
	pkig	cAMP-dependent protein kinase inhibitor gamma. (76 aa)
	LOC108276969	Neurofibromin isoform X3. (2756 aa)
	LOC108278595	Uncharacterized protein LOC108278567. (879 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
	sirt1	NAD-dependent protein deacetylase sirtuin-1 isoform X3. (731 aa)
	hmgcr	3-hydroxy-3-methylglutaryl coenzyme A reductase. (886 aa)
	men1	Menin. (616 aa)
	LOC108254707	cAMP-dependent protein kinase type II-beta regulatory subunit-like. (438 aa)
	cdk5rap3	CDK5 regulatory subunit-associated protein 3. (504 aa)
	LOC108272579	Dysbindin-like isoform X1. (188 aa)
	cdkn1a	Cyclin-dependent kinase inhibitor 1 isoform X1. (175 aa)
	irak3	Interleukin-1 receptor-associated kinase 3. (609 aa)
	tnfaip3	Tumor necrosis factor alpha-induced protein 3. (764 aa)
	cdkn2d	Cyclin-dependent kinase 4 inhibitor D. (170 aa)
	LOC108280031	Cyclin-dependent kinase inhibitor 1B-like. (157 aa)
	fbxo7	F-box only protein 7 isoform X1. (505 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (451 aa)
	LOC108274779	Cyclin-dependent kinase inhibitor 1C-like. (191 aa)
	ENSIPUP00000021843	Secreted frizzled-related protein 2 like. (231 aa)
	LOC108278928	3-hydroxy-3-methylglutaryl coenzyme A reductase. (858 aa)
	prkar1a	cAMP-dependent protein kinase type I-alpha regulatory subunit. (379 aa)
	LOC108274040	cAMP-dependent protein kinase type I-alpha regulatory subunit. (376 aa)
	LOC108280806	Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (158 aa)
	LOC108269231	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	sorl1	Sortilin-related receptor isoform X1. (2208 aa)
	tfap4	Transcription factor AP-4 isoform X1. (350 aa)
	ENSIPUP00000017806	Cyclin-dependent kinase inhibitor 1D. (147 aa)
	LOC108272203	Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (210 aa)
	cdkn1b	Cyclin-dependent kinase inhibitor 1B. (170 aa)
	spry4	Protein sprouty homolog 4. (312 aa)
	lats1	Serine/threonine-protein kinase LATS1. (1065 aa)
	LOC108259026	Protein sprouty homolog 2-like. (333 aa)
	paqr3	Progestin and adipoQ receptor family member 3 isoform X1. (312 aa)
	gba	Glucosylceramidase. (531 aa)
	lrp5	Low-density lipoprotein receptor-related protein 5. (1534 aa)
	LOC108279299	Protein sprouty homolog 2-like. (283 aa)
	LOC108265715	cAMP-dependent protein kinase type II-alpha regulatory subunit-like. (396 aa)
	bmp4	Bone morphogenetic protein 4. (402 aa)
	dusp19	Dual specificity protein phosphatase 19. (214 aa)
	myocd	Myocardin isoform X3. (1080 aa)
	lrp6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
	cdk5rap1	CDK5 regulatory subunit-associated protein 1 isoform X1. (574 aa)
	LOC108273817	Protein HEXIM-like. (344 aa)
	LOC108264167	Bone morphogenetic protein 2-like. (420 aa)
	lats2	Serine/threonine-protein kinase LATS2. (1145 aa)
	nf1	Neurofibromin isoform X5. (2745 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (598 aa)
	dusp10	Dual specificity protein phosphatase 10 isoform X1. (461 aa)
	LOC108263810	Cyclin-dependent kinase 4 inhibitor B-like. (172 aa)
	cdkn2c	Cyclin-dependent kinase 4 inhibitor C. (168 aa)
	LOC108255556	SH2B adapter protein 3-like. (346 aa)
	prkar1b	cAMP-dependent protein kinase type I-beta regulatory subunit. (444 aa)
	spry1	Protein sprouty homolog 1. (294 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSIPUP00000017806	LOC108263810	ENSIPUP00000017806	ENSIPUP00000002789	Cyclin-dependent kinase inhibitor 1D.	Cyclin-dependent kinase 4 inhibitor B-like.	0.529
ENSIPUP00000017806	cdkn2c	ENSIPUP00000017806	ENSIPUP00000002046	Cyclin-dependent kinase inhibitor 1D.	Cyclin-dependent kinase 4 inhibitor C.	0.476
ENSIPUP00000021843	lrp5	ENSIPUP00000021843	ENSIPUP00000011389	Secreted frizzled-related protein 2 like.	Low-density lipoprotein receptor-related protein 5.	0.450
ENSIPUP00000021843	lrp6	ENSIPUP00000021843	ENSIPUP00000007137	Secreted frizzled-related protein 2 like.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.450
LOC108254707	LOC108265715	ENSIPUP00000027063	ENSIPUP00000010419	cAMP-dependent protein kinase type II-beta regulatory subunit-like.	cAMP-dependent protein kinase type II-alpha regulatory subunit-like.	0.901
LOC108254707	LOC108274040	ENSIPUP00000027063	ENSIPUP00000020870	cAMP-dependent protein kinase type II-beta regulatory subunit-like.	cAMP-dependent protein kinase type I-alpha regulatory subunit.	0.903
LOC108254707	LOC108275286	ENSIPUP00000027063	ENSIPUP00000034303	cAMP-dependent protein kinase type II-beta regulatory subunit-like.	cAMP-dependent protein kinase type II-beta regulatory subunit-like.	0.906
LOC108254707	prkar1a	ENSIPUP00000027063	ENSIPUP00000021680	cAMP-dependent protein kinase type II-beta regulatory subunit-like.	cAMP-dependent protein kinase type I-alpha regulatory subunit.	0.903
LOC108254707	prkar1b	ENSIPUP00000027063	ENSIPUP00000001026	cAMP-dependent protein kinase type II-beta regulatory subunit-like.	cAMP-dependent protein kinase type I-beta regulatory subunit.	0.903
LOC108259026	spry1	ENSIPUP00000013787	ENSIPUP00000000362	Protein sprouty homolog 2-like.	Protein sprouty homolog 1.	0.683
LOC108259206	LOC108263810	ENSIPUP00000032875	ENSIPUP00000002789	Cyclin-dependent kinase inhibitor 1B-like.	Cyclin-dependent kinase 4 inhibitor B-like.	0.529
LOC108259206	cdkn2c	ENSIPUP00000032875	ENSIPUP00000002046	Cyclin-dependent kinase inhibitor 1B-like.	Cyclin-dependent kinase 4 inhibitor C.	0.476
LOC108263810	ENSIPUP00000017806	ENSIPUP00000002789	ENSIPUP00000017806	Cyclin-dependent kinase 4 inhibitor B-like.	Cyclin-dependent kinase inhibitor 1D.	0.529
LOC108263810	LOC108259206	ENSIPUP00000002789	ENSIPUP00000032875	Cyclin-dependent kinase 4 inhibitor B-like.	Cyclin-dependent kinase inhibitor 1B-like.	0.529
LOC108263810	LOC108274779	ENSIPUP00000002789	ENSIPUP00000022125	Cyclin-dependent kinase 4 inhibitor B-like.	Cyclin-dependent kinase inhibitor 1C-like.	0.529
LOC108263810	LOC108280031	ENSIPUP00000002789	ENSIPUP00000022867	Cyclin-dependent kinase 4 inhibitor B-like.	Cyclin-dependent kinase inhibitor 1B-like.	0.529
LOC108263810	cdkn1a	ENSIPUP00000002789	ENSIPUP00000025700	Cyclin-dependent kinase 4 inhibitor B-like.	Cyclin-dependent kinase inhibitor 1 isoform X1.	0.618
LOC108263810	cdkn1b	ENSIPUP00000002789	ENSIPUP00000017117	Cyclin-dependent kinase 4 inhibitor B-like.	Cyclin-dependent kinase inhibitor 1B.	0.529
LOC108263810	myocd	ENSIPUP00000002789	ENSIPUP00000007272	Cyclin-dependent kinase 4 inhibitor B-like.	Myocardin isoform X3.	0.439
LOC108263810	nf1	ENSIPUP00000002789	ENSIPUP00000005123	Cyclin-dependent kinase 4 inhibitor B-like.	Neurofibromin isoform X5.	0.421