STRINGSTRING
CNOT2 CNOT2 angel1 angel1 pde12 pde12 xrn2 xrn2 cnot8 cnot8 dis3l2 dis3l2 LOC108275399 LOC108275399 angel2 angel2 exosc9 exosc9 eri1 eri1 toe1 toe1 dcp2 dcp2 exd2 exd2 gnl3 gnl3 cpsf3 cpsf3 dis3 dis3 exosc10 exosc10 trir trir LOC108269158 LOC108269158 rexo2 rexo2 LOC108278618 LOC108278618 dis3l dis3l lrrc27 lrrc27 LOC108275083 LOC108275083 noct noct LOC108269372 LOC108269372 exosc2 exosc2 xrn1 xrn1 LOC108270067 LOC108270067 PNPT1 PNPT1 eri2 eri2 LOC108258427 LOC108258427 exosc7 exosc7 pan2 pan2 cnot6l cnot6l pan3 pan3 exosc8 exosc8 exosc3 exosc3 usb1 usb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CNOT2CCR4-NOT transcription complex subunit 2. (551 aa)
angel1Protein angel homolog 1. (750 aa)
pde122',5'-phosphodiesterase 12. (584 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (965 aa)
cnot8CCR4-NOT transcription complex subunit 8 isoform X1. (285 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (985 aa)
LOC108275399Ribonuclease ZC3H12A-like. (623 aa)
angel2Protein angel homolog 2. (525 aa)
exosc9Exosome complex component RRP45. (395 aa)
eri13'-5' exoribonuclease 1. (333 aa)
toe1Target of EGR1 protein 1. (508 aa)
dcp2m7GpppN-mRNA hydrolase. (388 aa)
exd2Exonuclease 3'-5' domain-containing protein 2 isoform X1. (631 aa)
gnl3Guanine nucleotide-binding protein-like 3. (526 aa)
cpsf3Cleavage and polyadenylation specificity factor subunit 3. (738 aa)
dis3Exosome complex exonuclease RRP44; Belongs to the RNR ribonuclease family. (951 aa)
exosc10Exosome component 10. (900 aa)
trirUncharacterized protein C19orf43 homolog. (170 aa)
LOC108269158CCR4-NOT transcription complex subunit 7. (286 aa)
rexo2Oligoribonuclease, mitochondrial. (271 aa)
LOC108278618CCR4-NOT transcription complex subunit 6. (556 aa)
dis3lDIS3-like exonuclease 1; Belongs to the RNR ribonuclease family. (1055 aa)
lrrc27Leucine-rich repeat-containing protein 27. (388 aa)
LOC108275083CCR4-NOT transcription complex subunit 2 isoform X1. (545 aa)
noctNocturnin isoform X1. (432 aa)
LOC108269372CCR4-NOT transcription complex subunit 6-like. (558 aa)
exosc2Exosome complex exonuclease rrp4. (294 aa)
xrn15'-3' exoribonuclease 1. (1665 aa)
LOC108270067Ribonuclease ZC3H12A-like. (605 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (713 aa)
eri2ERI1 exoribonuclease 2. (521 aa)
LOC108258427poly(A)-specific ribonuclease PARN-like. (596 aa)
exosc7Exosome complex exonuclease rrp42. (295 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1194 aa)
cnot6lCCR4-NOT transcription complex subunit 6-like. (549 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (804 aa)
exosc8Exosome complex exonuclease rrp43. (337 aa)
exosc3Exosome complex component RRP40. (246 aa)
usb1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (298 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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