36 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108279085	Diablo homolog, mitochondrial-like. (232 aa)
	tm198	Transmembrane protein 198 isoform X1. (339 aa)
	LOC108272558	Uncharacterized protein LOC108272558. (217 aa)
	LOC108273334	Non-syndromic hearing impairment protein 5 homolog. (512 aa)
	LOC108266082	Uncharacterized protein LOC108266082. (241 aa)
	LOC108266429	Uncharacterized protein LOC108266429 isoform X1. (114 aa)
	LOC108266428	Uncharacterized protein LOC108266428 isoform X4. (111 aa)
	LOC108280779	Septin-5 isoform X3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (370 aa)
	LOC108278924	Septin-5-like isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (523 aa)
	LOC108267037	Transmembrane protein 198-B-like. (386 aa)
	LOC108255238	Transmembrane protein 198-like isoform X1. (343 aa)
	tmem198	Transmembrane protein 198. (354 aa)
	ENSIPUP00000020603	annotation not available (660 aa)
	LOC108270970	Apoptosis regulator BAX-like. (202 aa)
	filip1l	Filamin A-interacting protein 1-like isoform X1. (1185 aa)
	BAX	BCL2 associated X, apoptosis regulator. (176 aa)
	bax	Apoptosis regulator BAX. (189 aa)
	Tep1	Telomerase associated protein 1. (88 aa)
	casp9	Caspase-9 isoform X2; Belongs to the peptidase C14A family. (432 aa)
	LOC108273362	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	LOC108278350	Diablo homolog, mitochondrial-like. (265 aa)
	LOC108256206	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
	LOC108274750	Apoptosis regulator BAX-like. (199 aa)
	casp7	Caspase-7 isoform X1; Belongs to the peptidase C14A family. (310 aa)
	ENSIPUP00000025403	annotation not available (128 aa)
	apaf1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1236 aa)
	Sept5	Septin 5. (90 aa)
	apip	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (242 aa)
	LOC108260860	Caspase-3-like; Belongs to the peptidase C14A family. (287 aa)
	aven	Cell death regulator Aven. (342 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	LOC108265487	LOW QUALITY PROTEIN: septin-5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (487 aa)
	xiap	E3 ubiquitin-protein ligase XIAP isoform X2. (437 aa)
	LOC108269206	E3 ubiquitin-protein ligase XIAP-like isoform X1. (386 aa)
	gsdme	Non-syndromic hearing impairment protein 5. (484 aa)
	ENSIPUP00000006017	annotation not available (106 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAX	LOC108270970	ENSIPUP00000022885	ENSIPUP00000021392	BCL2 associated X, apoptosis regulator.	Apoptosis regulator BAX-like.	0.656
BAX	LOC108272558	ENSIPUP00000022885	ENSIPUP00000008740	BCL2 associated X, apoptosis regulator.	Uncharacterized protein LOC108272558.	0.489
BAX	LOC108273362	ENSIPUP00000022885	ENSIPUP00000027951	BCL2 associated X, apoptosis regulator.	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.657
BAX	LOC108278350	ENSIPUP00000022885	ENSIPUP00000026051	BCL2 associated X, apoptosis regulator.	Diablo homolog, mitochondrial-like.	0.515
BAX	LOC108279085	ENSIPUP00000022885	ENSIPUP00000007968	BCL2 associated X, apoptosis regulator.	Diablo homolog, mitochondrial-like.	0.515
BAX	apaf1	ENSIPUP00000022885	ENSIPUP00000026028	BCL2 associated X, apoptosis regulator.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.587
ENSIPUP00000025403	LOC108270970	ENSIPUP00000025403	ENSIPUP00000021392	annotation not available	Apoptosis regulator BAX-like.	0.639
ENSIPUP00000025403	LOC108272558	ENSIPUP00000025403	ENSIPUP00000008740	annotation not available	Uncharacterized protein LOC108272558.	0.489
ENSIPUP00000025403	LOC108273362	ENSIPUP00000025403	ENSIPUP00000027951	annotation not available	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.657
ENSIPUP00000025403	LOC108278350	ENSIPUP00000025403	ENSIPUP00000026051	annotation not available	Diablo homolog, mitochondrial-like.	0.515
ENSIPUP00000025403	LOC108279085	ENSIPUP00000025403	ENSIPUP00000007968	annotation not available	Diablo homolog, mitochondrial-like.	0.515
ENSIPUP00000025403	apaf1	ENSIPUP00000025403	ENSIPUP00000026028	annotation not available	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.587
LOC108255238	LOC108273362	ENSIPUP00000018545	ENSIPUP00000027951	Transmembrane protein 198-like isoform X1.	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.525
LOC108255238	Tep1	ENSIPUP00000018545	ENSIPUP00000024541	Transmembrane protein 198-like isoform X1.	Telomerase associated protein 1.	0.401
LOC108255238	apaf1	ENSIPUP00000018545	ENSIPUP00000026028	Transmembrane protein 198-like isoform X1.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.741
LOC108256206	LOC108260860	ENSIPUP00000024564	ENSIPUP00000034973	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Caspase-3-like; Belongs to the peptidase C14A family.	0.494
LOC108256206	LOC108273362	ENSIPUP00000024564	ENSIPUP00000027951	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.468
LOC108256206	apaf1	ENSIPUP00000024564	ENSIPUP00000026028	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.533
LOC108256206	casp9	ENSIPUP00000024564	ENSIPUP00000028681	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Caspase-9 isoform X2; Belongs to the peptidase C14A family.	0.534
LOC108256206	mapk1	ENSIPUP00000024564	ENSIPUP00000030101	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.946