15 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sh2b1	SH2B adapter protein 1 isoform X1. (878 aa)
	ghr	Growth hormone receptor precursor. (555 aa)
	cul1	Cullin 1. (861 aa)
	LOC108280547	Prolactin; Belongs to the somatotropin/prolactin family. (227 aa)
	LOC108279639	Prolactin-like. (252 aa)
	LOC108280768	Cullin-1; Belongs to the cullin family. (777 aa)
	LOC108255897	Tyrosine-protein kinase. (1121 aa)
	prlr	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily. (584 aa)
	jak2	Tyrosine-protein kinase. (1115 aa)
	LOC100305005	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family. (200 aa)
	LOC108264905	Growth hormone receptor-like. (578 aa)
	LOC108276625	Somatolactin. (227 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (201 aa)
	LOC108279000	E3 ubiquitin-protein ligase RBX1-like. (108 aa)
	rbx1	E3 ubiquitin-protein ligase RBX1. (108 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100305005	LOC108264905	ENSIPUP00000027839	ENSIPUP00000028334	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family.	Growth hormone receptor-like.	0.982
LOC100305005	LOC108279639	ENSIPUP00000027839	ENSIPUP00000009595	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family.	Prolactin-like.	0.726
LOC100305005	LOC108280547	ENSIPUP00000027839	ENSIPUP00000009385	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family.	Prolactin; Belongs to the somatotropin/prolactin family.	0.750
LOC100305005	ghr	ENSIPUP00000027839	ENSIPUP00000007036	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family.	Growth hormone receptor precursor.	0.982
LOC100305005	prlr	ENSIPUP00000027839	ENSIPUP00000023913	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.	0.841
LOC108255897	LOC108264905	ENSIPUP00000021369	ENSIPUP00000028334	Tyrosine-protein kinase.	Growth hormone receptor-like.	0.624
LOC108255897	LOC108279639	ENSIPUP00000021369	ENSIPUP00000009595	Tyrosine-protein kinase.	Prolactin-like.	0.417
LOC108255897	LOC108280547	ENSIPUP00000021369	ENSIPUP00000009385	Tyrosine-protein kinase.	Prolactin; Belongs to the somatotropin/prolactin family.	0.417
LOC108255897	LOC108280768	ENSIPUP00000021369	ENSIPUP00000013535	Tyrosine-protein kinase.	Cullin-1; Belongs to the cullin family.	0.413
LOC108255897	cul1	ENSIPUP00000021369	ENSIPUP00000007459	Tyrosine-protein kinase.	Cullin 1.	0.413
LOC108255897	ghr	ENSIPUP00000021369	ENSIPUP00000007036	Tyrosine-protein kinase.	Growth hormone receptor precursor.	0.624
LOC108255897	jak2	ENSIPUP00000021369	ENSIPUP00000025760	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC108255897	prlr	ENSIPUP00000021369	ENSIPUP00000023913	Tyrosine-protein kinase.	Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily.	0.626
LOC108255897	sh2b1	ENSIPUP00000021369	ENSIPUP00000002396	Tyrosine-protein kinase.	SH2B adapter protein 1 isoform X1.	0.763
LOC108255897	skp1	ENSIPUP00000021369	ENSIPUP00000030698	Tyrosine-protein kinase.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.469
LOC108264905	LOC100305005	ENSIPUP00000028334	ENSIPUP00000027839	Growth hormone receptor-like.	Somatotropin; Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation; Belongs to the somatotropin/prolactin family.	0.982
LOC108264905	LOC108255897	ENSIPUP00000028334	ENSIPUP00000021369	Growth hormone receptor-like.	Tyrosine-protein kinase.	0.624
LOC108264905	LOC108276625	ENSIPUP00000028334	ENSIPUP00000030302	Growth hormone receptor-like.	Somatolactin.	0.841
LOC108264905	LOC108279639	ENSIPUP00000028334	ENSIPUP00000009595	Growth hormone receptor-like.	Prolactin-like.	0.553
LOC108264905	LOC108280547	ENSIPUP00000028334	ENSIPUP00000009385	Growth hormone receptor-like.	Prolactin; Belongs to the somatotropin/prolactin family.	0.553