STRINGSTRING
mknk1 mknk1 grb2 grb2 LOC108260120 LOC108260120 LOC108277863 LOC108277863 mapk1 mapk1 LOC108276199 LOC108276199 braf braf LOC108256206 LOC108256206 ENSIPUP00000024252 ENSIPUP00000024252 LOC108278138 LOC108278138 rps27a rps27a LOC108269204 LOC108269204 mknk2 mknk2 LOC108269225 LOC108269225 LOC108277698 LOC108277698 cbl cbl LOC108259026 LOC108259026 LOC108256494 LOC108256494 ppp2ca ppp2ca uba52 uba52 LOC108255075 LOC108255075 ppp2cb ppp2cb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mknk1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (459 aa)
grb2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
LOC108260120Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (589 aa)
LOC108277863Fibronectin type-III domain-containing protein 3a-like isoform X1. (1241 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
LOC108276199Tyrosine-protein kinase. (543 aa)
brafSerine/threonine-protein kinase B-raf. (782 aa)
LOC108256206Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
ENSIPUP00000024252annotation not available (77 aa)
LOC108278138MAP kinase-interacting serine/threonine-protein kinase 2-like isoform X1; Belongs to the protein kinase superfamily. (126 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
LOC108269204Fibronectin type-III domain-containing protein 3A-like isoform X1. (1169 aa)
mknk2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (476 aa)
LOC108269225E3 ubiquitin-protein ligase CBL-like isoform X1. (625 aa)
LOC108277698Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like. (589 aa)
cblE3 ubiquitin-protein ligase CBL. (911 aa)
LOC108259026Protein sprouty homolog 2-like. (333 aa)
LOC108256494Growth factor receptor-bound protein 2. (217 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
LOC108255075Tyrosine-protein kinase. (533 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.