STRINGSTRING
plch1 plch1 LOC108277652 LOC108277652 tasor tasor plcl1 plcl1 LOC108273053 LOC108273053 plcd1 plcd1 plce1 plce1 ippk ippk inpp5d inpp5d LOC108265505 LOC108265505 LOC108266487 LOC108266487 itpkc itpkc LOC108259491 LOC108259491 ipmk ipmk ip6k1 ip6k1 LOC108269684 LOC108269684 LOC108269686 LOC108269686 LOC108257830 LOC108257830 ocrl ocrl sash3 sash3 isyna1 isyna1 inpp5a inpp5a LOC108272115 LOC108272115 PLCB1 PLCB1 LOC108258041 LOC108258041 plcb2 plcb2 LOC108268467 LOC108268467 LOC108255881 LOC108255881 ppip5k2 ppip5k2 ENSIPUP00000001869 ENSIPUP00000001869 LOC108267602 LOC108267602 LOC108258212 LOC108258212 LOC108263300 LOC108263300 impa1 impa1 LOC108280636 LOC108280636 ENSIPUP00000004727 ENSIPUP00000004727 minpp1 minpp1 LOC108270447 LOC108270447 pten pten LOC108268790 LOC108268790 LOC108273813 LOC108273813 inpp4a inpp4a plcb1 plcb1 PLCB4 PLCB4 plcl2 plcl2 miox miox LOC108279338 LOC108279338 samd5 samd5 sash1 sash1 inpp4b inpp4b inpp1 inpp1 plcg2 plcg2 LOC108255045 LOC108255045 itpka itpka impa2 impa2 LOC108271898 LOC108271898 LOC108276637 LOC108276637 itpk1 itpk1 ppip5k1 ppip5k1 LOC108272042 LOC108272042 LOC108268863 LOC108268863 plch2 plch2 samsn1 samsn1 nudt4 nudt4 plcd3 plcd3 plcg1 plcg1 LOC108275142 LOC108275142 inpp5b inpp5b inppl1 inppl1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
plch1Phosphoinositide phospholipase C. (1745 aa)
LOC108277652SAM domain-containing protein SAMSN-1-like. (393 aa)
tasorProtein TASOR isoform X8. (1856 aa)
plcl1Phosphoinositide phospholipase C. (1132 aa)
LOC108273053Type I inositol 3,4-bisphosphate 4-phosphatase-like isoform X1. (983 aa)
plcd1Phosphoinositide phospholipase C. (765 aa)
plce11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1. (2117 aa)
ippkInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (486 aa)
inpp5dPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1118 aa)
LOC108265505Type I inositol 1,4,5-trisphosphate 5-phosphatase-like isoform X1. (394 aa)
LOC108266487Phosphoinositide phospholipase C. (746 aa)
itpkcKinase; Belongs to the inositol phosphokinase (IPK) family. (702 aa)
LOC108259491Phosphoinositide phospholipase C. (751 aa)
ipmkKinase; Belongs to the inositol phosphokinase (IPK) family. (424 aa)
ip6k1Kinase; Belongs to the inositol phosphokinase (IPK) family. (428 aa)
LOC108269684Multiple inositol polyphosphate phosphatase 1-like; Belongs to the histidine acid phosphatase family. (456 aa)
LOC108269686annotation not available (442 aa)
LOC108257830Inositol-tetrakisphosphate 1-kinase-like. (387 aa)
ocrlInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (975 aa)
sash3SAM and SH3 domain-containing protein 3. (388 aa)
isyna1Inositol-3-phosphate synthase 1. (549 aa)
inpp5aType I inositol 1,4,5-trisphosphate 5-phosphatase isoform X2. (412 aa)
LOC108272115Kinase; Belongs to the inositol phosphokinase (IPK) family. (457 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1244 aa)
LOC1082580411-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1267 aa)
plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1239 aa)
LOC108268467Kinase; Belongs to the inositol phosphokinase (IPK) family. (606 aa)
LOC108255881Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like isoform X1. (580 aa)
ppip5k2Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1329 aa)
ENSIPUP00000001869annotation not available (95 aa)
LOC1082676021-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1246 aa)
LOC108258212Kinase; Belongs to the inositol phosphokinase (IPK) family. (630 aa)
LOC108263300Kinase; Belongs to the inositol phosphokinase (IPK) family. (392 aa)
impa1Inositol-1-monophosphatase. (282 aa)
LOC108280636Phosphoinositide phospholipase C. (778 aa)
ENSIPUP00000004727annotation not available (151 aa)
minpp1Multiple inositol polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family. (468 aa)
LOC108270447SAM and SH3 domain-containing protein 1-like isoform X1. (1027 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
LOC108268790Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1214 aa)
LOC108273813Phosphoinositide phospholipase C. (780 aa)
inpp4aType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (995 aa)
plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1217 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
plcl2Phosphoinositide phospholipase C. (1080 aa)
mioxInositol oxygenase isoform X1. (285 aa)
LOC108279338Kinase; Belongs to the inositol phosphokinase (IPK) family. (426 aa)
samd5Sterile alpha motif domain-containing protein 5 isoform X4. (182 aa)
sash1SAM and SH3 domain-containing protein 1 isoform X2. (1171 aa)
inpp4bType II inositol 3,4-bisphosphate 4-phosphatase isoform X1. (927 aa)
inpp1Inositol polyphosphate 1-phosphatase. (380 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1263 aa)
LOC108255045Protein TASOR-like isoform X2. (1792 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (428 aa)
impa2Inositol-1-monophosphatase. (283 aa)
LOC108271898Diphosphoinositol polyphosphate phosphohydrolase 1-like isoform X1. (230 aa)
LOC108276637Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A-like. (516 aa)
itpk1Inositol-tetrakisphosphate 1-kinase. (414 aa)
ppip5k1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1369 aa)
LOC108272042Kinase; Belongs to the inositol phosphokinase (IPK) family. (481 aa)
LOC108268863Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B-like isoform X1. (1247 aa)
plch2Phosphoinositide phospholipase C. (1547 aa)
samsn1SAM domain-containing protein SAMSN-1. (630 aa)
nudt4Diphosphoinositol polyphosphate phosphohydrolase 2 isoform X1. (190 aa)
plcd3Phosphoinositide phospholipase C. (785 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1306 aa)
LOC108275142Diphosphoinositol polyphosphate phosphohydrolase 3-beta-like. (173 aa)
inpp5bType II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (894 aa)
inppl1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A-like. (683 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.