91 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108279029	Lymphocyte cytosolic protein 2-like. (494 aa)
	ENSIPUP00000036938	annotation not available (366 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	ENSIPUP00000032472	annotation not available (110 aa)
	LOC108276232	Tyrosine-protein phosphatase non-receptor type 22-like isoform X1. (1143 aa)
	LOC108259845	piggyBac transposable element-derived protein 4-like. (597 aa)
	chuk	Inhibitor of Nuclear factor kappa-B kinase subunit alpha. (756 aa)
	map3k20	Mitogen-activated protein kinase kinase kinase MLT. (796 aa)
	LOC108277126	F-box/WD repeat-containing protein 11 isoform X1. (525 aa)
	cd3e	T-cell surface glycoprotein CD3 epsilon chain isoform X3. (187 aa)
	cd3g	T-cell surface glycoprotein CD3 gamma chain. (165 aa)
	LOC108257355	3-phosphoinositide-dependent protein kinase 1-like. (509 aa)
	itk	Tyrosine-protein kinase. (616 aa)
	card11	Caspase recruitment domain-containing protein 11 isoform X2. (1144 aa)
	ENSIPUP00000026753	annotation not available (361 aa)
	LOC108269686	annotation not available (442 aa)
	ptpn12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (701 aa)
	LOC108273087	Growth factor receptor-bound protein 2-like isoform X2. (318 aa)
	ENSIPUP00000025519	annotation not available (130 aa)
	ube2n	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	LOC108258503	piggyBac transposable element-derived protein 4-like. (591 aa)
	ENSIPUP00000024142	annotation not available (159 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1306 aa)
	malt1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X2. (790 aa)
	rps27a	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
	LOC108258222	NF-kappa-B inhibitor alpha-like. (308 aa)
	psma7	Proteasome subunit alpha type. (251 aa)
	LOC108267562	Non-specific serine/threonine protein kinase. (504 aa)
	LOC108266872-2	piggyBac transposable element-derived protein 4-like isoform X1. (551 aa)
	bcl10	B-cell lymphoma/leukemia 10 isoform X1. (248 aa)
	LOC108268214	Uncharacterized protein LOC108268214. (851 aa)
	grap2	GRB2-related adapter protein 2. (265 aa)
	ENSIPUP00000019761	Si:ch211-130m23.5. (664 aa)
	ENSIPUP00000019727	annotation not available (584 aa)
	ikbkg	NF-kappa-B essential modulator. (568 aa)
	nfkbia	NF-kappa-B inhibitor alpha. (320 aa)
	tab2	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (673 aa)
	cd247	T-cell surface glycoprotein CD3 zeta chain precursor. (153 aa)
	ENSIPUP00000016429	annotation not available (122 aa)
	inpp5d	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1118 aa)
	map3k7	Mitogen-activated protein kinase kinase kinase 7. (550 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	LOC108260438	Protein spinster homolog 3-like isoform X1. (525 aa)
	LOC108260072	Protein spinster homolog 3-like isoform X1. (506 aa)
	LOC108278019	piggyBac transposable element-derived protein 4-like isoform X1. (614 aa)
	LOC108269586	Uncharacterized protein LOC108269586. (190 aa)
	ENSIPUP00000013982	annotation not available (153 aa)
	ENSIPUP00000013970	annotation not available (138 aa)
	ENSIPUP00000013961	annotation not available (142 aa)
	ENSIPUP00000013925	annotation not available (153 aa)
	ENSIPUP00000013863	annotation not available (145 aa)
	ENSIPUP00000013843	annotation not available (202 aa)
	ENSIPUP00000013817	annotation not available (111 aa)
	ENSIPUP00000013788	annotation not available (123 aa)
	ENSIPUP00000013704	annotation not available (142 aa)
	ENSIPUP00000013655	annotation not available (116 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (579 aa)
	ENSIPUP00000013622	annotation not available (158 aa)
	ENSIPUP00000013604	annotation not available (115 aa)
	ENSIPUP00000013590	annotation not available (139 aa)
	ENSIPUP00000013583	annotation not available (114 aa)
	ENSIPUP00000013569	annotation not available (279 aa)
	ENSIPUP00000013545	annotation not available (117 aa)
	ENSIPUP00000013526	annotation not available (130 aa)
	LOC108275024	F-box/WD repeat-containing protein 11-like isoform X1. (567 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (727 aa)
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1263 aa)
	ENSIPUP00000009176	annotation not available (577 aa)
	pak1	Non-specific serine/threonine protein kinase. (546 aa)
	csk	Tyrosine-protein kinase. (449 aa)
	ub2v1	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	kxd1	kxDL motif-containing protein 1 isoform X2. (187 aa)
	LOC108271158	Receptor-interacting serine/threonine-protein kinase 2-like isoform X1. (531 aa)
	ENSIPUP00000007666	annotation not available (428 aa)
	uba52	ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
	fyb1	FYN-binding protein isoform X1. (807 aa)
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	LOC108266369	Immunoglobulin superfamily member 3-like isoform X3. (1040 aa)
	LOC108266368	Immunoglobulin superfamily member 2-like isoform X1. (1136 aa)
	LOC108273902	piggyBac transposable element-derived protein 4-like. (609 aa)
	LOC108255212	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	spns1	Protein spinster homolog 1. (505 aa)
	pag1	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (377 aa)
	nck1	Cytoplasmic protein. (381 aa)
	ENSIPUP00000000678	annotation not available (595 aa)
	LOC108264442	3-phosphoinositide-dependent protein kinase 1-like isoform X1. (537 aa)
	LOC108270956	Mucosa-associated lymphoid tissue lymphoma translocation protein 1-like. (802 aa)
	ikbkb	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (776 aa)
	pak2	Non-specific serine/threonine protein kinase. (531 aa)
	ENSIPUP00000037378	annotation not available (513 aa)
	optn	Optineurin. (550 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	ENSIPUP00000019761	ENSIPUP00000015381	ENSIPUP00000019761	Tyrosine-protein kinase.	Si:ch211-130m23.5.	0.463
CSK	LOC108269686	ENSIPUP00000015381	ENSIPUP00000026656	Tyrosine-protein kinase.	annotation not available	0.509
CSK	LOC108273087	ENSIPUP00000015381	ENSIPUP00000025679	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2-like isoform X2.	0.428
CSK	LOC108276232	ENSIPUP00000015381	ENSIPUP00000032431	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type 22-like isoform X1.	0.732
CSK	cd247	ENSIPUP00000015381	ENSIPUP00000016754	Tyrosine-protein kinase.	T-cell surface glycoprotein CD3 zeta chain precursor.	0.640
CSK	cd3e	ENSIPUP00000015381	ENSIPUP00000029007	Tyrosine-protein kinase.	T-cell surface glycoprotein CD3 epsilon chain isoform X3.	0.624
CSK	cd3g	ENSIPUP00000015381	ENSIPUP00000028981	Tyrosine-protein kinase.	T-cell surface glycoprotein CD3 gamma chain.	0.463
CSK	grap2	ENSIPUP00000015381	ENSIPUP00000019871	Tyrosine-protein kinase.	GRB2-related adapter protein 2.	0.428
CSK	nck1	ENSIPUP00000015381	ENSIPUP00000001267	Tyrosine-protein kinase.	Cytoplasmic protein.	0.466
CSK	pag1	ENSIPUP00000015381	ENSIPUP00000001882	Tyrosine-protein kinase.	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1.	0.912
CSK	plcg1	ENSIPUP00000015381	ENSIPUP00000024034	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.463
CSK	plcg2	ENSIPUP00000015381	ENSIPUP00000009177	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.463
CSK	pten	ENSIPUP00000015381	ENSIPUP00000004920	Tyrosine-protein kinase.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.509
CSK	ptpn12	ENSIPUP00000015381	ENSIPUP00000026394	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.722
CSK	uba52	ENSIPUP00000015381	ENSIPUP00000007381	Tyrosine-protein kinase.	ubiquitin-60S ribosomal protein L40 isoform X1.	0.415
ENSIPUP00000000678	LOC108279029	ENSIPUP00000000678	ENSIPUP00000036100	annotation not available	Lymphocyte cytosolic protein 2-like.	0.509
ENSIPUP00000000678	cd247	ENSIPUP00000000678	ENSIPUP00000016754	annotation not available	T-cell surface glycoprotein CD3 zeta chain precursor.	0.829
ENSIPUP00000000678	cd3e	ENSIPUP00000000678	ENSIPUP00000029007	annotation not available	T-cell surface glycoprotein CD3 epsilon chain isoform X3.	0.883
ENSIPUP00000007666	LOC108279029	ENSIPUP00000007666	ENSIPUP00000036100	annotation not available	Lymphocyte cytosolic protein 2-like.	0.509
ENSIPUP00000007666	cd247	ENSIPUP00000007666	ENSIPUP00000016754	annotation not available	T-cell surface glycoprotein CD3 zeta chain precursor.	0.829