STRINGSTRING
ngfr ngfr ikbkb ikbkb LOC108271158 LOC108271158 ripk2 ripk2 myd88 myd88 sqstm1 sqstm1 irak1 irak1 prkci prkci LOC108276493 LOC108276493 rps27a rps27a LOC108273578 LOC108273578 traf6 traf6 ngf ngf
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ngfrTumor necrosis factor receptor superfamily member 16 isoform X1. (378 aa)
ikbkbInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (776 aa)
LOC108271158Receptor-interacting serine/threonine-protein kinase 2-like isoform X1. (531 aa)
ripk2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (579 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (279 aa)
sqstm1Sequestosome-1. (460 aa)
irak1Interleukin-1 receptor-associated kinase 1 isoform X4. (718 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (509 aa)
LOC108276493Neurotrophin-7-like; Belongs to the NGF-beta family. (211 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
LOC108273578Tumor necrosis factor receptor superfamily member 16-like. (409 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
ngfBeta-nerve growth factor; Belongs to the NGF-beta family. (197 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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