STRINGSTRING
LOC108258501 LOC108258501 pb9la pb9la LOC108258508 LOC108258508 psmb7 psmb7 tp53 tp53 psmb4 psmb4 psme2 psme2 psmb6 psmb6 psmd9 psmd9 LOC108267915 LOC108267915 psme3 psme3 psa6 psa6 psmd11 psmd11 cop1 cop1 psmc6 psmc6 psmc5 psmc5 psmb1 psmb1 psme4 psme4 psmd12 psmd12 psmb2 psmb2 rps27a rps27a LOC100304914 LOC100304914 LOC108258228 LOC108258228 psma7 psma7 psma4 psma4 psma6 psma6 psmd3 psmd3 psmb3 psmb3 LOC108270933 LOC108270933 psmd4 psmd4 psmd14 psmd14 psmd7 psmd7 psmc4 psmc4 atm atm psd13 psd13 psma1 psma1 psmb5 psmb5 kxd1 kxd1 uba52 uba52 psmd5 psmd5 LOC108274842 LOC108274842 psmc3 psmc3 psma3 psma3 psmf1 psmf1 psmc1 psmc1 psmd8 psmd8 psmd10 psmd10 psme1 psme1 psmd6 psmd6 psmc2 psmc2 psmd1 psmd1 psma2 psma2 psa2 psa2 psma5 psma5 PSMB8 PSMB8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108258501Proteasome subunit beta. (274 aa)
pb9laProteasome subunit beta. (214 aa)
LOC108258508Proteasome subunit beta. (218 aa)
psmb7Proteasome subunit beta. (318 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (376 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (215 aa)
psme2Proteasome activator complex subunit 2. (242 aa)
psmb6Proteasome subunit beta. (244 aa)
psmd926S proteasome non-ATPase regulatory subunit 9. (213 aa)
LOC108267915Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (394 aa)
psme3Proteasome activator complex subunit 3. (256 aa)
psa6Proteasome subunit alpha type. (246 aa)
psmd1126S proteasome non-ATPase regulatory subunit 11B. (422 aa)
cop1E3 ubiquitin-protein ligase RFWD2 isoform X1. (692 aa)
psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (371 aa)
psmc526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
psmb1Proteasome subunit beta. (237 aa)
psme4Proteasome activator complex subunit 4 isoform X2. (1827 aa)
psmd1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
psmb2Proteasome subunit beta. (199 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
LOC100304914Proteasome subunit alpha type. (251 aa)
LOC108258228Proteasome subunit alpha type-6-like. (228 aa)
psma7Proteasome subunit alpha type. (251 aa)
psma4Proteasome subunit alpha type. (261 aa)
psma6Proteasome subunit alpha type. (246 aa)
psmd326S proteasome non-ATPase regulatory subunit 3. (514 aa)
psmb3Proteasome subunit beta. (205 aa)
LOC10827093326S proteasome non-ATPase regulatory subunit 13-like isoform X1. (378 aa)
psmd426S proteasome non-ATPase regulatory subunit 4. (373 aa)
psmd1426S proteasome non-ATPase regulatory subunit 14. (300 aa)
psmd726S proteasome non-ATPase regulatory subunit 7. (326 aa)
psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (412 aa)
atmNon-specific serine/threonine protein kinase. (3076 aa)
psd1326S proteasome non-ATPase regulatory subunit 13. (400 aa)
psma1Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
psmb5Proteasome subunit beta. (277 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
psmd526S proteasome non-ATPase regulatory subunit 5. (505 aa)
LOC108274842Proteasome subunit beta type-7-like. (278 aa)
psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (427 aa)
psma3Proteasome subunit alpha type. (255 aa)
psmf1Proteasome inhibitor PI31 subunit. (270 aa)
psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
psmd826S proteasome non-ATPase regulatory subunit 8. (267 aa)
psmd1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
psme1Proteasome activator complex subunit 1. (246 aa)
psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
psmc226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (965 aa)
psma2Proteasome 20S subunit alpha 2. (234 aa)
psa2Proteasome subunit alpha type. (234 aa)
psma5Proteasome subunit alpha type. (241 aa)
PSMB8Proteasome subunit beta. (274 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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