59 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sox4	Transcription factor SOX. (359 aa)
	xiap	E3 ubiquitin-protein ligase XIAP isoform X2. (437 aa)
	LOC108269206	E3 ubiquitin-protein ligase XIAP-like isoform X1. (386 aa)
	sox10	Transcription factor SOX-10. (468 aa)
	LOC108264340	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
	cby1	Protein chibby homolog 1. (125 aa)
	LOC108271216	Amino-terminal enhancer of split-like isoform X2. (211 aa)
	ENSIPUP00000002356	annotation not available (121 aa)
	LOC108271164	Protein groucho-1-like isoform X4. (353 aa)
	LOC108271319	Transducin-like enhancer protein 1. (790 aa)
	sox6	Transcription factor SOX-6 isoform X7. (759 aa)
	LOC108265410	Transcription factor 7-like 1-B. (527 aa)
	ctnnbip1	Beta-catenin-interacting protein 1. (81 aa)
	LOC108266170	Transcription factor Sox-1a. (345 aa)
	sox13	Transcription factor SOX-13 isoform X1. (655 aa)
	hmgxb4	HMG domain-containing protein 4. (619 aa)
	LOC108267652	Transcription factor Sox-19b-like. (294 aa)
	uba52	ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
	bhmg1	Basic helix-loop-helix and HMG box domain-containing protein 1 isoform X1. (479 aa)
	ENSIPUP00000007963	annotation not available (87 aa)
	kxd1	kxDL motif-containing protein 1 isoform X2. (187 aa)
	LOC108259077	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	lef1	Lymphoid enhancer-binding factor 1 isoform X1. (362 aa)
	akt3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	sox18	Transcription factor SOX-18. (431 aa)
	zbtb44	Zinc finger and BTB domain-containing protein 44 isoform X1. (657 aa)
	sox21	Transcription factor SOX-21. (229 aa)
	ctnnb1	Catenin beta-1 isoform X3. (789 aa)
	LOC108259890	Transcription factor Sox-9-A-like. (464 aa)
	sox8	Transcription factor SOX-8. (457 aa)
	sox9	Transcription factor SOX-9. (449 aa)
	LOC108269901	Exportin-1. (1071 aa)
	sox14	Transcription factor SOX-14. (244 aa)
	LOC108273322	Transcription factor SOX. (338 aa)
	LOC108266914	Transcription factor Sox-21-B-like. (242 aa)
	rps27a	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
	LOC108267240	Transcription factor Sox-17-alpha-like. (305 aa)
	tcf7l2	Transcription factor 7-like 2 isoform X2. (628 aa)
	LOC108267806	Transcription factor Sox-17-alpha-like. (442 aa)
	sox7	Transcription factor Sox-7. (398 aa)
	LOC108273085	HMG box-containing protein 4-like isoform X2. (201 aa)
	ENSIPUP00000024679	High mobility group protein 2-like 1. (92 aa)
	LOC108256545	Catenin beta-1-like. (779 aa)
	LOC108280588	Amino-terminal enhancer of split-like isoform X2. (205 aa)
	LOC108280589	Transducin-like enhancer protein 4 isoform X1. (341 aa)
	LOC108259372	Transducin-like enhancer protein 3 isoform X1. (777 aa)
	LOC108267737	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2544 aa)
	tcf7	Transcription factor 7 isoform X6. (417 aa)
	SOX1	Transcription factor SOX-1. (293 aa)
	LOC108260177	Transcription factor Sox-19a-like. (281 aa)
	sox3	Transcription factor SOX-3 isoform X1. (236 aa)
	LOC108264729	Protein groucho-2 isoform X2. (766 aa)
	sox11-a	Transcription factor SOX. (370 aa)
	LOC108269454	Transcription factor SOX. (371 aa)
	ENSIPUP00000036008	annotation not available (118 aa)
	sox5	Transcription factor SOX-5. (713 aa)
	LOC108258411	Exportin-1-like. (1095 aa)
	SOX2	Transcription factor SOX-2. (334 aa)
	LOC108255020	Transcription factor SOX. (351 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSIPUP00000002356	LOC108256545	ENSIPUP00000002356	ENSIPUP00000024768	annotation not available	Catenin beta-1-like.	0.413
ENSIPUP00000002356	LOC108265410	ENSIPUP00000002356	ENSIPUP00000005324	annotation not available	Transcription factor 7-like 1-B.	0.660
ENSIPUP00000002356	ctnnb1	ENSIPUP00000002356	ENSIPUP00000015789	annotation not available	Catenin beta-1 isoform X3.	0.413
ENSIPUP00000002356	lef1	ENSIPUP00000002356	ENSIPUP00000013133	annotation not available	Lymphoid enhancer-binding factor 1 isoform X1.	0.663
ENSIPUP00000002356	rps27a	ENSIPUP00000002356	ENSIPUP00000022626	annotation not available	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.440
ENSIPUP00000002356	tcf7	ENSIPUP00000002356	ENSIPUP00000030727	annotation not available	Transcription factor 7 isoform X6.	0.663
ENSIPUP00000002356	tcf7l2	ENSIPUP00000002356	ENSIPUP00000024052	annotation not available	Transcription factor 7-like 2 isoform X2.	0.660
ENSIPUP00000024679	tcf7	ENSIPUP00000024679	ENSIPUP00000030727	High mobility group protein 2-like 1.	Transcription factor 7 isoform X6.	0.400
ENSIPUP00000036008	LOC108256545	ENSIPUP00000036008	ENSIPUP00000024768	annotation not available	Catenin beta-1-like.	0.578
ENSIPUP00000036008	LOC108265410	ENSIPUP00000036008	ENSIPUP00000005324	annotation not available	Transcription factor 7-like 1-B.	0.443
ENSIPUP00000036008	ctnnb1	ENSIPUP00000036008	ENSIPUP00000015789	annotation not available	Catenin beta-1 isoform X3.	0.578
ENSIPUP00000036008	lef1	ENSIPUP00000036008	ENSIPUP00000013133	annotation not available	Lymphoid enhancer-binding factor 1 isoform X1.	0.443
ENSIPUP00000036008	sox10	ENSIPUP00000036008	ENSIPUP00000001124	annotation not available	Transcription factor SOX-10.	0.443
ENSIPUP00000036008	sox13	ENSIPUP00000036008	ENSIPUP00000006519	annotation not available	Transcription factor SOX-13 isoform X1.	0.607
ENSIPUP00000036008	sox5	ENSIPUP00000036008	ENSIPUP00000036009	annotation not available	Transcription factor SOX-5.	0.720
ENSIPUP00000036008	sox6	ENSIPUP00000036008	ENSIPUP00000005000	annotation not available	Transcription factor SOX-6 isoform X7.	0.752
ENSIPUP00000036008	tcf7	ENSIPUP00000036008	ENSIPUP00000030727	annotation not available	Transcription factor 7 isoform X6.	0.611
ENSIPUP00000036008	tcf7l2	ENSIPUP00000036008	ENSIPUP00000024052	annotation not available	Transcription factor 7-like 2 isoform X2.	0.443
LOC108255020	LOC108256545	ENSIPUP00000036720	ENSIPUP00000024768	Transcription factor SOX.	Catenin beta-1-like.	0.476
LOC108255020	LOC108265410	ENSIPUP00000036720	ENSIPUP00000005324	Transcription factor SOX.	Transcription factor 7-like 1-B.	0.462