26 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108263675	Mitogen-activated protein kinase. (439 aa)
	LOC108255212	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	uba52	ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
	LOC108274195	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1; Belongs to the protein kinase superfamily. (425 aa)
	LOC108271158	Receptor-interacting serine/threonine-protein kinase 2-like isoform X1. (531 aa)
	kxd1	kxDL motif-containing protein 1 isoform X2. (187 aa)
	ub2v1	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	nod1	Nucleotide-binding oligomerization domain-containing protein 1. (946 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (579 aa)
	map3k7	Mitogen-activated protein kinase kinase kinase 7. (550 aa)
	tab2	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (673 aa)
	irak1	Interleukin-1 receptor-associated kinase 1 isoform X4. (718 aa)
	ikbkg	NF-kappa-B essential modulator. (568 aa)
	LOC108274025	Mitogen-activated protein kinase. (384 aa)
	rps27a	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
	LOC108278438	Mitogen-activated protein kinase. (447 aa)
	tab3	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (554 aa)
	nod2	Nucleotide-binding oligomerization domain-containing protein 2. (981 aa)
	tab1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (495 aa)
	ube2n	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	mapk9	Mitogen-activated protein kinase. (421 aa)
	map3k20	Mitogen-activated protein kinase kinase kinase MLT. (796 aa)
	map2k7	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (445 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	map2k4	Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily. (420 aa)
	optn	Optineurin. (550 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108255212	LOC108271158	ENSIPUP00000003446	ENSIPUP00000007939	Ubiquitin-conjugating enzyme E2 variant 1.	Receptor-interacting serine/threonine-protein kinase 2-like isoform X1.	0.510
LOC108255212	ikbkg	ENSIPUP00000003446	ENSIPUP00000019557	Ubiquitin-conjugating enzyme E2 variant 1.	NF-kappa-B essential modulator.	0.686
LOC108255212	irak1	ENSIPUP00000003446	ENSIPUP00000019227	Ubiquitin-conjugating enzyme E2 variant 1.	Interleukin-1 receptor-associated kinase 1 isoform X4.	0.536
LOC108255212	map3k20	ENSIPUP00000003446	ENSIPUP00000029930	Ubiquitin-conjugating enzyme E2 variant 1.	Mitogen-activated protein kinase kinase kinase MLT.	0.510
LOC108255212	map3k7	ENSIPUP00000003446	ENSIPUP00000015661	Ubiquitin-conjugating enzyme E2 variant 1.	Mitogen-activated protein kinase kinase kinase 7.	0.510
LOC108255212	optn	ENSIPUP00000003446	ENSIPUP00000034663	Ubiquitin-conjugating enzyme E2 variant 1.	Optineurin.	0.686
LOC108255212	ripk2	ENSIPUP00000003446	ENSIPUP00000013628	Ubiquitin-conjugating enzyme E2 variant 1.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.510
LOC108255212	rps27a	ENSIPUP00000003446	ENSIPUP00000022626	Ubiquitin-conjugating enzyme E2 variant 1.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.999
LOC108255212	tab1	ENSIPUP00000003446	ENSIPUP00000025352	Ubiquitin-conjugating enzyme E2 variant 1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1.	0.524
LOC108255212	tab2	ENSIPUP00000003446	ENSIPUP00000017236	Ubiquitin-conjugating enzyme E2 variant 1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.	0.964
LOC108255212	tab3	ENSIPUP00000003446	ENSIPUP00000023511	Ubiquitin-conjugating enzyme E2 variant 1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3.	0.964
LOC108255212	traf6	ENSIPUP00000003446	ENSIPUP00000032978	Ubiquitin-conjugating enzyme E2 variant 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.731
LOC108255212	ub2v1	ENSIPUP00000003446	ENSIPUP00000008321	Ubiquitin-conjugating enzyme E2 variant 1.	Ubiquitin-conjugating enzyme E2 variant 1.	0.925
LOC108255212	uba52	ENSIPUP00000003446	ENSIPUP00000007381	Ubiquitin-conjugating enzyme E2 variant 1.	ubiquitin-60S ribosomal protein L40 isoform X1.	0.999
LOC108255212	ube2n	ENSIPUP00000003446	ENSIPUP00000025480	Ubiquitin-conjugating enzyme E2 variant 1.	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.	0.976
LOC108263675	LOC108274195	ENSIPUP00000000359	ENSIPUP00000007411	Mitogen-activated protein kinase.	Dual specificity mitogen-activated protein kinase kinase 4-like isoform X1; Belongs to the protein kinase superfamily.	0.987
LOC108263675	map2k4	ENSIPUP00000000359	ENSIPUP00000033218	Mitogen-activated protein kinase.	Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily.	0.988
LOC108263675	map2k7	ENSIPUP00000000359	ENSIPUP00000031342	Mitogen-activated protein kinase.	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	0.988
LOC108263675	map3k20	ENSIPUP00000000359	ENSIPUP00000029930	Mitogen-activated protein kinase.	Mitogen-activated protein kinase kinase kinase MLT.	0.421
LOC108263675	map3k7	ENSIPUP00000000359	ENSIPUP00000015661	Mitogen-activated protein kinase.	Mitogen-activated protein kinase kinase kinase 7.	0.423