STRINGSTRING
fzd8 fzd8 dvl2 dvl2 LOC108266250 LOC108266250 LOC108266251 LOC108266251 LOC108266249 LOC108266249 ppp2cb ppp2cb LOC108267535 LOC108267535 lrp6 lrp6 apc apc gsk3a gsk3a wnt3a wnt3a ppp2ca ppp2ca apc2 apc2 lrp5 lrp5 wnt1 wnt1 hmgxb3 hmgxb3 ctnnb1 ctnnb1 LOC108277698 LOC108277698 fzd2 fzd2 LOC108268006 LOC108268006 ENSIPUP00000018803 ENSIPUP00000018803 ppp2r5d ppp2r5d dvl3 dvl3 csnk1a1 csnk1a1 LOC108269231 LOC108269231 LOC108258646 LOC108258646 LOC108256545 LOC108256545 amer1 amer1 LOC108257929 LOC108257929 LOC108268465 LOC108268465 lrp4 lrp4 LOC108268464 LOC108268464 cav3 cav3 axin1 axin1 frat2 frat2 ppp2r5a ppp2r5a PPP2R5E PPP2R5E dvl1 dvl1 LOC108260120 LOC108260120 LOC108257814 LOC108257814 fzd5 fzd5 gsk3b gsk3b wnt8b wnt8b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzd8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
dvl2Segment polarity protein dishevelled homolog DVL-2. (746 aa)
LOC108266250Putative methyltransferase DDB_G0268948. (271 aa)
LOC108266251Uncharacterized methyltransferase-like C25B8.10. (271 aa)
LOC108266249Uncharacterized methyltransferase-like C25B8.10. (271 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC108267535Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (503 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
apcAdenomatous polyposis coli protein isoform X1. (2760 aa)
gsk3aGlycogen synthase kinase-3 alpha isoform X1; Belongs to the protein kinase superfamily. (440 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
apc2Adenomatous polyposis coli protein 2. (2087 aa)
lrp5Low-density lipoprotein receptor-related protein 5. (1534 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
hmgxb3HMG domain-containing protein 3 isoform X1. (1293 aa)
ctnnb1Catenin beta-1 isoform X3. (789 aa)
LOC108277698Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like. (589 aa)
fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
LOC108268006Segment polarity protein dishevelled homolog DVL-3-like. (662 aa)
ENSIPUP00000018803annotation not available (129 aa)
ppp2r5dSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (633 aa)
dvl3Segment polarity protein dishevelled homolog DVL-3. (670 aa)
csnk1a1Casein kinase I isoform X4; Belongs to the protein kinase superfamily. (336 aa)
LOC108269231Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
LOC108258646Glycogen synthase kinase-3 beta-like isoform X1; Belongs to the protein kinase superfamily. (422 aa)
LOC108256545Catenin beta-1-like. (779 aa)
amer1APC membrane recruitment protein 1. (973 aa)
LOC108257929Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (468 aa)
LOC108268465Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
lrp4Low-density lipoprotein receptor-related protein 4. (1900 aa)
LOC108268464Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
axin1Axin-1 isoform X1. (806 aa)
frat2GSK-3-binding protein FRAT2. (148 aa)
ppp2r5aSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (505 aa)
PPP2R5ESerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (476 aa)
dvl1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (730 aa)
LOC108260120Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (589 aa)
LOC108257814Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (580 aa)
fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
gsk3bGlycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (421 aa)
wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (34%) [HD]