43 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fzd8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	dvl2	Segment polarity protein dishevelled homolog DVL-2. (746 aa)
	LOC108266250	Putative methyltransferase DDB_G0268948. (271 aa)
	LOC108266251	Uncharacterized methyltransferase-like C25B8.10. (271 aa)
	LOC108266249	Uncharacterized methyltransferase-like C25B8.10. (271 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	LOC108267535	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (503 aa)
	lrp6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
	apc	Adenomatous polyposis coli protein isoform X1. (2760 aa)
	gsk3a	Glycogen synthase kinase-3 alpha isoform X1; Belongs to the protein kinase superfamily. (440 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	apc2	Adenomatous polyposis coli protein 2. (2087 aa)
	lrp5	Low-density lipoprotein receptor-related protein 5. (1534 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
	hmgxb3	HMG domain-containing protein 3 isoform X1. (1293 aa)
	ctnnb1	Catenin beta-1 isoform X3. (789 aa)
	LOC108277698	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like. (589 aa)
	fzd2	Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
	LOC108268006	Segment polarity protein dishevelled homolog DVL-3-like. (662 aa)
	ENSIPUP00000018803	annotation not available (129 aa)
	ppp2r5d	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (633 aa)
	dvl3	Segment polarity protein dishevelled homolog DVL-3. (670 aa)
	csnk1a1	Casein kinase I isoform X4; Belongs to the protein kinase superfamily. (336 aa)
	LOC108269231	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC108258646	Glycogen synthase kinase-3 beta-like isoform X1; Belongs to the protein kinase superfamily. (422 aa)
	LOC108256545	Catenin beta-1-like. (779 aa)
	amer1	APC membrane recruitment protein 1. (973 aa)
	LOC108257929	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (468 aa)
	LOC108268465	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	lrp4	Low-density lipoprotein receptor-related protein 4. (1900 aa)
	LOC108268464	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
	axin1	Axin-1 isoform X1. (806 aa)
	frat2	GSK-3-binding protein FRAT2. (148 aa)
	ppp2r5a	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (505 aa)
	PPP2R5E	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (476 aa)
	dvl1	Segment polarity protein dishevelled homolog DVL-1 isoform X1. (730 aa)
	LOC108260120	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (589 aa)
	LOC108257814	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (580 aa)
	fzd5	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
	gsk3b	Glycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (421 aa)
	wnt8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSIPUP00000018803	LOC108256545	ENSIPUP00000018803	ENSIPUP00000024768	annotation not available	Catenin beta-1-like.	0.828
ENSIPUP00000018803	LOC108257814	ENSIPUP00000018803	ENSIPUP00000033796	annotation not available	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.444
ENSIPUP00000018803	LOC108257929	ENSIPUP00000018803	ENSIPUP00000025162	annotation not available	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.430
ENSIPUP00000018803	LOC108258646	ENSIPUP00000018803	ENSIPUP00000022541	annotation not available	Glycogen synthase kinase-3 beta-like isoform X1; Belongs to the protein kinase superfamily.	0.827
ENSIPUP00000018803	LOC108260120	ENSIPUP00000018803	ENSIPUP00000033638	annotation not available	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform.	0.468
ENSIPUP00000018803	LOC108267535	ENSIPUP00000018803	ENSIPUP00000005763	annotation not available	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.483
ENSIPUP00000018803	LOC108268006	ENSIPUP00000018803	ENSIPUP00000018725	annotation not available	Segment polarity protein dishevelled homolog DVL-3-like.	0.789
ENSIPUP00000018803	LOC108268464	ENSIPUP00000018803	ENSIPUP00000027285	annotation not available	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.618
ENSIPUP00000018803	LOC108268465	ENSIPUP00000018803	ENSIPUP00000027268	annotation not available	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.618
ENSIPUP00000018803	LOC108277698	ENSIPUP00000018803	ENSIPUP00000018052	annotation not available	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like.	0.468
ENSIPUP00000018803	PPP2R5E	ENSIPUP00000018803	ENSIPUP00000032801	annotation not available	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.430
ENSIPUP00000018803	amer1	ENSIPUP00000018803	ENSIPUP00000024852	annotation not available	APC membrane recruitment protein 1.	0.833
ENSIPUP00000018803	apc	ENSIPUP00000018803	ENSIPUP00000008487	annotation not available	Adenomatous polyposis coli protein isoform X1.	0.866
ENSIPUP00000018803	apc2	ENSIPUP00000018803	ENSIPUP00000011279	annotation not available	Adenomatous polyposis coli protein 2.	0.823
ENSIPUP00000018803	cav3	ENSIPUP00000018803	ENSIPUP00000027712	annotation not available	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.460
ENSIPUP00000018803	csnk1a1	ENSIPUP00000018803	ENSIPUP00000019973	annotation not available	Casein kinase I isoform X4; Belongs to the protein kinase superfamily.	0.891
ENSIPUP00000018803	ctnnb1	ENSIPUP00000018803	ENSIPUP00000015789	annotation not available	Catenin beta-1 isoform X3.	0.885
ENSIPUP00000018803	dvl1	ENSIPUP00000018803	ENSIPUP00000033052	annotation not available	Segment polarity protein dishevelled homolog DVL-1 isoform X1.	0.751
ENSIPUP00000018803	dvl2	ENSIPUP00000018803	ENSIPUP00000001569	annotation not available	Segment polarity protein dishevelled homolog DVL-2.	0.794
ENSIPUP00000018803	dvl3	ENSIPUP00000018803	ENSIPUP00000019963	annotation not available	Segment polarity protein dishevelled homolog DVL-3.	0.788