STRINGSTRING
uba52 uba52 wnt3a wnt3a lrp5 lrp5 rnf43 rnf43 LGR6 LGR6 rps27a rps27a lgr5 lgr5 rspo1 rspo1 usp8 usp8 rspo3 rspo3 znrf3 znrf3 lgr4 lgr4 fzd6 fzd6 lrp4 lrp4 rspo2 rspo2 fzd5 fzd5 lrtm1 lrtm1 fzd4 fzd4 lrp6 lrp6 fzd8 fzd8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
lrp5Low-density lipoprotein receptor-related protein 5. (1534 aa)
rnf43E3 ubiquitin-protein ligase RNF43 isoform X1. (800 aa)
LGR6Leucine-rich repeat-containing G-protein coupled receptor 6. (904 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
lgr5Leucine-rich repeat-containing G-protein coupled receptor 5. (838 aa)
rspo1R-spondin-1 isoform X3. (266 aa)
usp8Ubiquitin carboxyl-terminal hydrolase 8. (1001 aa)
rspo3R-spondin-3. (312 aa)
znrf3E3 ubiquitin-protein ligase ZNRF3 isoform X1. (876 aa)
lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (957 aa)
fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (662 aa)
lrp4Low-density lipoprotein receptor-related protein 4. (1900 aa)
rspo2R-spondin-2 isoform X1. (269 aa)
fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
lrtm1Leucine-rich repeat and Transmembrane domain-containing protein 1. (349 aa)
fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1634 aa)
fzd8Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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