STRINGSTRING
LOC108259026 LOC108259026 LOC108262899 LOC108262899 fgf10 fgf10 grb2 grb2 fgf20 fgf20 LOC108260120 LOC108260120 LOC108268489 LOC108268489 LOC108277863 LOC108277863 mapk1 mapk1 LOC108268415 LOC108268415 LOC108276199 LOC108276199 LOC108279521 LOC108279521 braf braf LOC108256206 LOC108256206 ENSIPUP00000024252 ENSIPUP00000024252 LOC108278138 LOC108278138 fgf7 fgf7 fgf16 fgf16 rps27a rps27a fgfr2 fgfr2 LOC108269204 LOC108269204 fgf4 fgf4 fgf3 fgf3 mknk2 mknk2 mknk1 mknk1 LOC108269225 LOC108269225 LOC108277698 LOC108277698 LOC108269308 LOC108269308 cbl cbl fgf1-2 fgf1-2 fgf1 fgf1 fgf5 fgf5 LOC108274431 LOC108274431 LOC108256494 LOC108256494 frs2 frs2 ppp2ca ppp2ca fgf17 fgf17 LOC108266192 LOC108266192 uba52 uba52 fgf23 fgf23 LOC108278508 LOC108278508 LOC108255075 LOC108255075 ppp2cb ppp2cb fgf22 fgf22 fgf2 fgf2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108259026Protein sprouty homolog 2-like. (333 aa)
LOC108262899Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
grb2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
LOC108260120Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (589 aa)
LOC108268489Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
LOC108277863Fibronectin type-III domain-containing protein 3a-like isoform X1. (1241 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
LOC108268415Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC108276199Tyrosine-protein kinase. (543 aa)
LOC108279521Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (204 aa)
brafSerine/threonine-protein kinase B-raf. (782 aa)
LOC108256206Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
ENSIPUP00000024252annotation not available (77 aa)
LOC108278138MAP kinase-interacting serine/threonine-protein kinase 2-like isoform X1; Belongs to the protein kinase superfamily. (126 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
fgfr2Fibroblast growth factor receptor. (840 aa)
LOC108269204Fibronectin type-III domain-containing protein 3A-like isoform X1. (1169 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (185 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (265 aa)
mknk2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (476 aa)
mknk1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (459 aa)
LOC108269225E3 ubiquitin-protein ligase CBL-like isoform X1. (625 aa)
LOC108277698Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like. (589 aa)
LOC108269308Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa)
cblE3 ubiquitin-protein ligase CBL. (911 aa)
fgf1-2Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
LOC108274431Fibroblast growth factor 18-like isoform X1; Belongs to the heparin-binding growth factors family. (208 aa)
LOC108256494Growth factor receptor-bound protein 2. (217 aa)
frs2Fibroblast growth factor receptor substrate 2 isoform X1. (514 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
LOC108266192Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (69 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (254 aa)
LOC108278508Fibroblast growth factor 10-like. (314 aa)
LOC108255075Tyrosine-protein kinase. (533 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (151 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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