Your Input: | |
| | LOC108260489 | Histone H2B; Belongs to the histone H2B family. (117 aa) |
| | ube2i | SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (177 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa) |
| | LOC108262486 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa) |
| | LOC108262497 | Histone H4-like. (96 aa) |
| | pias4 | E3 SUMO-protein ligase PIAS4. (506 aa) |
| | LOC108262536 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa) |
| | LOC108261379 | Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa) |
| | LOC108262589 | Histone H4-like. (96 aa) |
| | LOC108255684 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | LOC108262596 | Histone H4-like. (96 aa) |
| | ENSIPUP00000002007 | annotation not available (133 aa) |
| | LOC108262617 | Histone H2B-like. (103 aa) |
| | LOC108262621 | Histone H4-like. (75 aa) |
| | ENSIPUP00000002141 | annotation not available (67 aa) |
| | LOC108262673 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | ENSIPUP00000002932 | annotation not available (108 aa) |
| | apbb1 | Amyloid beta A4 precursor protein-binding family B member 1. (747 aa) |
| | nbn | Nibrin. (831 aa) |
| | ENSIPUP00000005160 | annotation not available (81 aa) |
| | LOC108272432 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (102 aa) |
| | LOC108272324 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | abraxas1 | BRCA1-A complex subunit Abraxas. (393 aa) |
| | LOC108261983 | Histone H2B-like; Belongs to the histone H2B family. (88 aa) |
| | uba52 | ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa) |
| | mdc1 | Mediator of DNA damage checkpoint protein 1 isoform X2. (1909 aa) |
| | smarca5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1090 aa) |
| | kxd1 | kxDL motif-containing protein 1 isoform X2. (187 aa) |
| | ENSIPUP00000009144 | Histone H2B 3. (118 aa) |
| | LOC108277171 | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | ppp5c | Serine/threonine-protein phosphatase. (481 aa) |
| | uimc1 | BRCA1-A complex subunit RAP80 isoform X1. (960 aa) |
| | nsd2 | Histone-lysine N-methyltransferase NSD2 isoform X2. (1480 aa) |
| | babam1 | BRISC and BRCA1-A complex member 1. (369 aa) |
| | ENSIPUP00000011444 | annotation not available (131 aa) |
| | ENSIPUP00000011897 | annotation not available (218 aa) |
| | LOC108261425 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa) |
| | atm | Non-specific serine/threonine protein kinase. (3076 aa) |
| | LOC108261488 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | eya1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (604 aa) |
| | baz1b | Tyrosine-protein kinase BAZ1B isoform X1. (1573 aa) |
| | ENSIPUP00000012797 | annotation not available (109 aa) |
| | LOC108261379-2 | Histone H2B-like. (124 aa) |
| | ENSIPUP00000013437 | annotation not available (145 aa) |
| | LOC108261690 | Histone H4. (96 aa) |
| | ENSIPUP00000013757 | annotation not available (100 aa) |
| | babam2 | BRCA1-A complex subunit BRE. (386 aa) |
| | eya4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (644 aa) |
| | ube2v2 | Ubiquitin-conjugating enzyme E2 variant 2. (148 aa) |
| | brcc3 | Lys-63-specific deubiquitinase BRCC36 isoform X1. (260 aa) |
| | LOC108261712 | Histone H4-like. (81 aa) |
| | ENSIPUP00000016196 | annotation not available (490 aa) |
| | ENSIPUP00000016437 | annotation not available (175 aa) |
| | LOC108258592 | Histone H2A; Belongs to the histone H2A family. (132 aa) |
| | ENSIPUP00000017001 | annotation not available (67 aa) |
| | LOC108261860 | Histone H4-like. (96 aa) |
| | LOC108261861 | Histone H2B; Belongs to the histone H2B family. (125 aa) |
| | ENSIPUP00000017440 | annotation not available (144 aa) |
| | LOC108261901 | Histone H4-like. (96 aa) |
| | LOC108261899 | Histone H2B-like. (117 aa) |
| | ENSIPUP00000017662 | annotation not available (150 aa) |
| | LOC108255684-2 | Histone H4. (103 aa) |
| | LOC108261964 | Histone H2B; Belongs to the histone H2B family. (124 aa) |
| | LOC108261379-3 | Histone H2B-like. (124 aa) |
| | ENSIPUP00000018324 | annotation not available (150 aa) |
| | rad50 | DNA repair protein RAD50 isoform X1. (1311 aa) |
| | LOC108255684-3 | Histone H4. (103 aa) |
| | LOC108262131 | Histone H2B-like. (90 aa) |
| | ENSIPUP00000018991 | annotation not available (96 aa) |
| | ENSIPUP00000019080 | annotation not available (285 aa) |
| | LOC108255684-4 | Histone H4. (103 aa) |
| | LOC108255684-5 | Histone H4. (103 aa) |
| | LOC108262397 | Histone H4-like. (96 aa) |
| | LOC108262407 | Histone H2B; Belongs to the histone H2B family. (164 aa) |
| | LOC108280529 | Lysine-specific demethylase 4A-like isoform X1. (916 aa) |
| | kat5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (435 aa) |
| | rps27a | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa) |
| | abl1 | Tyrosine-protein kinase. (1089 aa) |
| | chek2 | Serine/threonine-protein kinase Chk2. (539 aa) |
| | LOC108260009 | Putative global transcription activator SNF2L1. (1016 aa) |
| | ube2n | Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | ankrd12 | Ankyrin repeat domain-containing protein 12 isoform X2. (2035 aa) |
| | eya3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (659 aa) |
| | LOC108255359 | Uncharacterized protein LOC108255359 isoform X2. (1394 aa) |
| | LOC108257257 | SUMO-conjugating enzyme UBC9-B. (157 aa) |
| | LOC108267915 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (394 aa) |
| | LOC108261097 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | rnf169 | E3 ubiquitin-protein ligase RNF169. (619 aa) |
| | rnf168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (461 aa) |
| | sumo1 | Small ubiquitin-related modifier. (131 aa) |
| | tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (376 aa) |
| | rnf8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (491 aa) |
| | brca1 | Breast cancer type 1 susceptibility protein isoform X2. (1369 aa) |
| | ENSIPUP00000033019 | annotation not available (92 aa) |
| | herc2 | E3 ubiquitin-protein ligase HERC2. (4717 aa) |
| | tp53bp1 | Tumor suppressor p53-binding protein 1 isoform X3. (1750 aa) |
| | ankrd11 | Ankyrin repeat domain-containing protein 11 isoform X2. (2820 aa) |
| | pwwp2a | PWWP domain-containing protein 2A. (668 aa) |
| | eya2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (476 aa) |
| | LOC108271011 | Lysine-specific demethylase 4B-like isoform X1. (1105 aa) |
