STRINGSTRING
ercc1 ercc1 rfc4 rfc4 ercc4 ercc4 pold3 pold3 pold2 pold2 rfc1 rfc1 rpa1 rpa1 uba52 uba52 kxd1 kxd1 ddb1 ddb1 ercc2 ercc2 pole4 pole4 pole3 pole3 bivm bivm ercc5 ercc5 rfc3 rfc3 gtf2h1 gtf2h1 cul4a cul4a LOC108272412 LOC108272412 rfc2 rfc2 pcna pcna pold1 pold1 gtf2h2c gtf2h2c rbx1 rbx1 chd1l chd1l LOC108279000 LOC108279000 rcbtb2 rcbtb2 ercc3 ercc3 rcbtb1 rcbtb1 gtf2h3 gtf2h3 parp1 parp1 pole pole rfc5 rfc5 gtf2h5 gtf2h5 cul4b cul4b parp3 parp3 rpa3 rpa3 pole2 pole2 gtf2h4 gtf2h4 parp2 parp2 rps27a rps27a rpa2 rpa2 pold4 pold4 polk polk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ercc1DNA excision repair protein ERCC-1. (367 aa)
rfc4Replication factor C subunit 4 isoform X1. (358 aa)
ercc4DNA repair endonuclease XPF. (899 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (471 aa)
pold2DNA polymerase delta subunit 2. (467 aa)
rfc1Replication factor C subunit 1. (1129 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
ddb1DNA damage-binding protein 1. (1140 aa)
ercc2TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (761 aa)
pole4DNA polymerase epsilon subunit 4. (125 aa)
pole3DNA polymerase epsilon subunit 3. (149 aa)
bivmBasic immunoglobulin-like variable motif-containing protein isoform X1. (504 aa)
ercc5DNA repair protein complementing XP-G cells. (1107 aa)
rfc3Replication factor C subunit 3. (356 aa)
gtf2h1General transcription factor IIH subunit 1. (549 aa)
cul4acullin-4A; Belongs to the cullin family. (741 aa)
LOC108272412Replication protein A 32 kDa subunit-like. (251 aa)
rfc2Replication factor C subunit 2. (357 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (297 aa)
pold1DNA polymerase. (1066 aa)
gtf2h2cGeneral transcription factor IIH subunit 2-like protein. (394 aa)
rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
chd1lchromodomain-helicase-DNA-binding protein 1-like. (1024 aa)
LOC108279000E3 ubiquitin-protein ligase RBX1-like. (108 aa)
rcbtb2RCC1 and BTB domain-containing protein 2. (540 aa)
ercc3TFIIH basal transcription factor complex helicase XPB subunit. (780 aa)
rcbtb1RCC1 and BTB domain-containing protein 1. (531 aa)
gtf2h3General transcription factor IIH subunit 3 isoform X1. (300 aa)
parp1Poly [ADP-ribose] polymerase. (1018 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
rfc5Replication factor C subunit 5. (339 aa)
gtf2h5General transcription factor IIH subunit 5 isoform X1. (71 aa)
cul4bcullin-4B; Belongs to the cullin family. (854 aa)
parp3Poly [ADP-ribose] polymerase. (524 aa)
rpa3Replication protein A 14 kDa subunit. (122 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (467 aa)
parp2Poly [ADP-ribose] polymerase. (629 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
rpa2Replication protein A 32 kDa subunit. (294 aa)
pold4DNA polymerase delta subunit 4. (109 aa)
polkDNA polymerase kappa. (927 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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