STRINGSTRING
mapkap1 mapkap1 ppp2ca ppp2ca LOC108277489 LOC108277489 atm atm phf20 phf20 akt3 akt3 ccna1 ccna1 LOC108260071 LOC108260071 SGK1 SGK1 daxx daxx kxd1 kxd1 ENSIPUP00000007434 ENSIPUP00000007434 mdm2 mdm2 mdm4 mdm4 LOC108257814 LOC108257814 LOC108260120 LOC108260120 mtor mtor LOC108264913 LOC108264913 cdk1 cdk1 ccna2 ccna2 LOC108257355 LOC108257355 akt1 akt1 LOC108267915 LOC108267915 rffl rffl tp53 tp53 uba52 uba52 LOC108268783 LOC108268783 LOC108279333 LOC108279333 LOC108277312 LOC108277312 ccng1 ccng1 LOC108277698 LOC108277698 cdk2 cdk2 mlst8 mlst8 ppp2cb ppp2cb LOC108264340 LOC108264340 txndc11 txndc11 prr5 prr5 usp7 usp7 rps27a rps27a chek2 chek2 LOC108264442 LOC108264442 rictor rictor LOC108259077 LOC108259077
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mapkap1Target of rapamycin complex 2 subunit MAPKAP1. (527 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC108277489Ubiquitin carboxyl-terminal hydrolase. (561 aa)
atmNon-specific serine/threonine protein kinase. (3076 aa)
phf20PHD finger protein 20 isoform X3. (940 aa)
akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ccna1cyclin-A1 isoform X2; Belongs to the cyclin family. (397 aa)
LOC108260071Ubiquitin carboxyl-terminal hydrolase. (542 aa)
SGK1Non-specific serine/threonine protein kinase. (690 aa)
daxxDeath domain-associated protein 6 isoform X1. (716 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
ENSIPUP00000007434annotation not available (165 aa)
mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (473 aa)
mdm4Protein Mdm4 isoform X2; Belongs to the MDM2/MDM4 family. (468 aa)
LOC108257814Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (580 aa)
LOC108260120Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (589 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2525 aa)
LOC108264913E3 ubiquitin-protein ligase RNF34-like isoform X1. (434 aa)
cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (302 aa)
ccna2cyclin-A2; Belongs to the cyclin family. (423 aa)
LOC1082573553-phosphoinositide-dependent protein kinase 1-like. (509 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
LOC108267915Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (394 aa)
rfflE3 ubiquitin-protein ligase rififylin isoform X1. (349 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (376 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
LOC108268783Proline-rich protein 5-like isoform X1. (441 aa)
LOC108279333E3 ubiquitin-protein ligase rififylin-like isoform X1. (260 aa)
LOC108277312E3 ubiquitin-protein ligase RNF34-like isoform X1. (388 aa)
ccng1Cyclin-G1; Belongs to the cyclin family. (299 aa)
LOC108277698Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like. (589 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (301 aa)
mlst8Target of rapamycin complex subunit LST8. (326 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC108264340Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
txndc11Thioredoxin domain-containing protein 11. (770 aa)
prr5Proline-rich protein 5 isoform X1. (439 aa)
usp7Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family. (1112 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
chek2Serine/threonine-protein kinase Chk2. (539 aa)
LOC1082644423-phosphoinositide-dependent protein kinase 1-like isoform X1. (537 aa)
rictorRapamycin-insensitive companion of mTOR isoform X2. (1568 aa)
LOC108259077Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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