STRINGSTRING
psme2 psme2 mcm9 mcm9 psmb6 psmb6 LOC108275335 LOC108275335 skp1 skp1 rcbtb1 rcbtb1 psmd9 psmd9 pole pole rfc5 rfc5 psme3 psme3 psa6 psa6 cdc27 cdc27 lig1 lig1 psmd11 psmd11 anapc1 anapc1 cdc26 cdc26 psmc6 psmc6 dna2 dna2 psmc5 psmc5 rpa3 rpa3 pole2 pole2 psmb1 psmb1 LOC108280911 LOC108280911 ccna2 ccna2 anapc2 anapc2 tm7sf3 tm7sf3 atad5 atad5 psme4 psme4 psmd12 psmd12 psmb2 psmb2 LOC108263846 LOC108263846 pola1 pola1 LOC108280318 LOC108280318 rps27a rps27a LOC100304914 LOC100304914 LOC108258228 LOC108258228 psma7 psma7 bicral bicral rpa2 rpa2 orc6 orc6 anapc15 anapc15 LOC108258154 LOC108258154 psma4 psma4 pold4 pold4 fzr1 fzr1 ccne1 ccne1 psma6 psma6 cdk2 cdk2 cdc6 cdc6 psmd3 psmd3 rfc4 rfc4 prim1 prim1 LOC108272959 LOC108272959 LOC108272957 LOC108272957 psmb3 psmb3 LOC108272412 LOC108272412 LOC108270933 LOC108270933 fam89a fam89a LOC108268046 LOC108268046 rfc3 rfc3 psmd4 psmd4 psmd14 psmd14 psmd7 psmd7 anapc16 anapc16 LOC108280894 LOC108280894 ccna1 ccna1 anapc7 anapc7 mcm2 mcm2 LOC108280768 LOC108280768 anapc4 anapc4 psmc4 psmc4 pola2 pola2 gins3 gins3 ube2s ube2s mcm3 mcm3 psd13 psd13 ENSIPUP00000011577 ENSIPUP00000011577 pole3 pole3 LOC108271213 LOC108271213 pole4 pole4 psma1 psma1 psmb5 psmb5 gins2 gins2 orc1 orc1 kxd1 kxd1 orc3 orc3 cul1 cul1 uba52 uba52 psmd5 psmd5 mcm8 mcm8 mcm5 mcm5 rpa1 rpa1 LOC108274842 LOC108274842 rfc1 rfc1 ube2c ube2c rfc2 rfc2 pcna pcna psmd1 psmd1 orc5 orc5 psmc2 psmc2 cdt1 cdt1 psmd6 psmd6 cdc16 cdc16 LOC108256709 LOC108256709 pold1 pold1 rbx1 rbx1 LOC108273255 LOC108273255 psma2 psma2 anapc11 anapc11 psa2 psa2 psma5 psma5 mcm6 mcm6 gins4 gins4 LOC108263058 LOC108263058 psmc3 psmc3 cdc23 cdc23 pold2 pold2 pold3 pold3 meiob meiob anapc10 anapc10 psma3 psma3 CCNE2 CCNE2 skp2 skp2 ENSIPUP00000002499 ENSIPUP00000002499 ENSIPUP00000002488 ENSIPUP00000002488 psmf1 psmf1 fen1 fen1 gmnn gmnn psmc1 psmc1 psmd8 psmd8 psmd10 psmd10 mcm7 mcm7 bicra bicra mcm4 mcm4 psme1 psme1 LOC108279000 LOC108279000 orc2 orc2 LOC108258499 LOC108258499 PSMB8 PSMB8 LOC108258501 LOC108258501 pb9la pb9la anapc5 anapc5 LOC108258508 LOC108258508 psmb7 psmb7 orc4 orc4 psmb4 psmb4 rcbtb2 rcbtb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psme2Proteasome activator complex subunit 2. (242 aa)
mcm9DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1097 aa)
psmb6Proteasome subunit beta. (244 aa)
LOC108275335G1/S-specific cyclin-E2-like; Belongs to the cyclin family. (392 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (201 aa)
rcbtb1RCC1 and BTB domain-containing protein 1. (531 aa)
psmd926S proteasome non-ATPase regulatory subunit 9. (213 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
rfc5Replication factor C subunit 5. (339 aa)
psme3Proteasome activator complex subunit 3. (256 aa)
psa6Proteasome subunit alpha type. (246 aa)
cdc27Cell division cycle protein 27 homolog isoform X1. (834 aa)
lig1DNA ligase. (946 aa)
psmd1126S proteasome non-ATPase regulatory subunit 11B. (422 aa)
anapc1Anaphase-promoting complex subunit 1 isoform X1. (1959 aa)
cdc26Anaphase-promoting complex subunit CDC26 isoform X1. (86 aa)
psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (371 aa)
dna2DNA replication ATP-dependent helicase/nuclease DNA2 isoform X4. (1343 aa)
psmc526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
rpa3Replication protein A 14 kDa subunit. (122 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC108280911Fizzy-related protein homolog isoform X1. (495 aa)
ccna2cyclin-A2; Belongs to the cyclin family. (423 aa)
anapc2Anaphase-promoting complex subunit 2 isoform X2; Belongs to the cullin family. (804 aa)
tm7sf3Transmembrane 7 superfamily member 3 isoform X1. (562 aa)
atad5ATPase family AAA domain-containing protein 5 isoform X1. (1798 aa)
psme4Proteasome activator complex subunit 4 isoform X2. (1827 aa)
psmd1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
psmb2Proteasome subunit beta. (199 aa)
LOC108263846DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (515 aa)
pola1DNA polymerase. (1457 aa)
LOC108280318LOW QUALITY PROTEIN: probable flap endonuclease 1 homolog. (325 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
LOC100304914Proteasome subunit alpha type. (251 aa)
LOC108258228Proteasome subunit alpha type-6-like. (228 aa)
psma7Proteasome subunit alpha type. (251 aa)
bicralGLTSCR1-like protein. (836 aa)
rpa2Replication protein A 32 kDa subunit. (294 aa)
orc6Origin recognition complex subunit 6 isoform X1. (260 aa)
anapc15Anaphase-promoting complex subunit 15. (165 aa)
LOC108258154DNA helicase; Belongs to the MCM family. (791 aa)
psma4Proteasome subunit alpha type. (261 aa)
pold4DNA polymerase delta subunit 4. (109 aa)
fzr1Fizzy-related protein homolog isoform X1. (496 aa)
ccne1G1/S-specific cyclin-E1 isoform X2; Belongs to the cyclin family. (404 aa)
psma6Proteasome subunit alpha type. (246 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (301 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (587 aa)
psmd326S proteasome non-ATPase regulatory subunit 3. (514 aa)
rfc4Replication factor C subunit 4 isoform X1. (358 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (442 aa)
LOC108272959Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
LOC108272957Ubiquitin-conjugating enzyme E2 E2-like; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
psmb3Proteasome subunit beta. (205 aa)
LOC108272412Replication protein A 32 kDa subunit-like. (251 aa)
LOC10827093326S proteasome non-ATPase regulatory subunit 13-like isoform X1. (378 aa)
fam89aProtein FAM89A. (171 aa)
LOC108268046Fizzy-related protein homolog. (486 aa)
rfc3Replication factor C subunit 3. (356 aa)
psmd426S proteasome non-ATPase regulatory subunit 4. (373 aa)
psmd1426S proteasome non-ATPase regulatory subunit 14. (300 aa)
psmd726S proteasome non-ATPase regulatory subunit 7. (326 aa)
anapc16Anaphase-promoting complex subunit 16. (84 aa)
LOC108280894DNA helicase; Belongs to the MCM family. (825 aa)
ccna1cyclin-A1 isoform X2; Belongs to the cyclin family. (397 aa)
anapc7Anaphase-promoting complex subunit 7. (565 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
LOC108280768Cullin-1; Belongs to the cullin family. (777 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (773 aa)
psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (412 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (614 aa)
gins3DNA replication complex GINS protein PSF3. (211 aa)
ube2sUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (228 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
psd1326S proteasome non-ATPase regulatory subunit 13. (400 aa)
ENSIPUP00000011577DNA replication ATP-dependent helicase/nuclease DNA2-like. (96 aa)
pole3DNA polymerase epsilon subunit 3. (149 aa)
LOC108271213C-C motif chemokine 20-like. (127 aa)
pole4DNA polymerase epsilon subunit 4. (125 aa)
psma1Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
psmb5Proteasome subunit beta. (277 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1030 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
orc3Origin recognition complex subunit 3 isoform X1. (718 aa)
cul1Cullin 1. (861 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
psmd526S proteasome non-ATPase regulatory subunit 5. (505 aa)
mcm8DNA helicase MCM8; Belongs to the MCM family. (852 aa)
mcm5DNA helicase; Belongs to the MCM family. (736 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
LOC108274842Proteasome subunit beta type-7-like. (278 aa)
rfc1Replication factor C subunit 1. (1129 aa)
ube2cUbiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (172 aa)
rfc2Replication factor C subunit 2. (357 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (297 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (965 aa)
orc5Origin recognition complex subunit 5. (445 aa)
psmc226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
cdt1DNA replication factor Cdt1. (672 aa)
psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
cdc16Cell division cycle protein 16 homolog isoform X1. (611 aa)
LOC108256709Ubiquitin-conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
pold1DNA polymerase. (1066 aa)
rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
LOC108273255ATPase family AAA domain-containing protein 5-like. (927 aa)
psma2Proteasome 20S subunit alpha 2. (234 aa)
anapc11Anaphase-promoting complex subunit 11 isoform X1. (88 aa)
psa2Proteasome subunit alpha type. (234 aa)
psma5Proteasome subunit alpha type. (241 aa)
mcm6DNA helicase; Belongs to the MCM family. (823 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
LOC108263058LOW QUALITY PROTEIN: DNA replication complex GINS protein PSF1-like. (230 aa)
psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (427 aa)
cdc23Cell division cycle protein 23 homolog. (585 aa)
pold2DNA polymerase delta subunit 2. (467 aa)
pold3DNA polymerase delta subunit 3 isoform X1. (471 aa)
meiobMeiosis-specific with OB domain-containing protein. (466 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
psma3Proteasome subunit alpha type. (255 aa)
CCNE2G1/S-specific cyclin-E2-like; Belongs to the cyclin family. (379 aa)
skp2S-phase kinase-associated protein 2. (411 aa)
ENSIPUP00000002499annotation not available (78 aa)
ENSIPUP00000002488annotation not available (80 aa)
psmf1Proteasome inhibitor PI31 subunit. (270 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
gmnnGeminin. (262 aa)
psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
psmd826S proteasome non-ATPase regulatory subunit 8. (267 aa)
psmd1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (722 aa)
bicraGlioma tumor suppressor candidate region gene 1 protein isoform X1. (1765 aa)
mcm4DNA helicase; Belongs to the MCM family. (845 aa)
psme1Proteasome activator complex subunit 1. (246 aa)
LOC108279000E3 ubiquitin-protein ligase RBX1-like. (108 aa)
orc2Origin recognition complex subunit 2. (576 aa)
LOC108258499Proteasome subunit beta. (277 aa)
PSMB8Proteasome subunit beta. (274 aa)
LOC108258501Proteasome subunit beta. (274 aa)
pb9laProteasome subunit beta. (214 aa)
anapc5Anaphase-promoting complex subunit 5. (767 aa)
LOC108258508Proteasome subunit beta. (218 aa)
psmb7Proteasome subunit beta. (318 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (428 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (215 aa)
rcbtb2RCC1 and BTB domain-containing protein 2. (540 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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