STRINGSTRING
slf1 slf1 orc6 orc6 kat5 kat5 LOC108258154 LOC108258154 LOC108260056 LOC108260056 psma4 psma4 LOC108262407 LOC108262407 LOC108262397 LOC108262397 LOC108255684-5 LOC108255684-5 LOC108255684-4 LOC108255684-4 cdc7 cdc7 LOC108270562 LOC108270562 ENSIPUP00000019080 ENSIPUP00000019080 ENSIPUP00000018991 ENSIPUP00000018991 143b1 143b1 LOC108262131 LOC108262131 LOC108255684-3 LOC108255684-3 rad50 rad50 psma6 psma6 cdk2 cdk2 ENSIPUP00000018324 ENSIPUP00000018324 143g1 143g1 tdrd3 tdrd3 cdc6 cdc6 psmd3 psmd3 LOC108278678 LOC108278678 LOC108261379-3 LOC108261379-3 LOC108261964 LOC108261964 LOC108255684-2 LOC108255684-2 ENSIPUP00000017847 ENSIPUP00000017847 rfc4 rfc4 ENSIPUP00000017662 ENSIPUP00000017662 LOC108261899 LOC108261899 LOC108261901 LOC108261901 ENSIPUP00000017440 ENSIPUP00000017440 LOC108261861 LOC108261861 LOC108261860 LOC108261860 ENSIPUP00000017001 ENSIPUP00000017001 psmb3 psmb3 LOC108272412 LOC108272412 LOC108258592 LOC108258592 LOC108270933 LOC108270933 atrip atrip ENSIPUP00000016437 ENSIPUP00000016437 ENSIPUP00000016196 ENSIPUP00000016196 LOC108271195 LOC108271195 LOC108261712 LOC108261712 LOC108257302 LOC108257302 brcc3 brcc3 rfc3 rfc3 babam2 babam2 psmd4 psmd4 psmd14 psmd14 psmd7 psmd7 LOC108280894 LOC108280894 psme1 psme1 mcm4 mcm4 ube2v2 ube2v2 LOC108260489 LOC108260489 mcm7 mcm7 psmd10 psmd10 blm blm exd2 exd2 psmd8 psmd8 psmc1 psmc1 mre11 mre11 LOC108262486 LOC108262486 LOC108262497 LOC108262497 pias4 pias4 LOC108262536 LOC108262536 rbbp8 rbbp8 LOC108261379 LOC108261379 LOC108262589 LOC108262589 LOC108255684 LOC108255684 LOC108262596 LOC108262596 ENSIPUP00000002007 ENSIPUP00000002007 LOC108262617 LOC108262617 LOC108262621 LOC108262621 ENSIPUP00000002141 ENSIPUP00000002141 LOC108262673 LOC108262673 psmf1 psmf1 LOC100305105 LOC100305105 chek1 chek1 psma3 psma3 wrn wrn ENSIPUP00000002932 ENSIPUP00000002932 meiob meiob LOC108265441 LOC108265441 psmc3 psmc3 nbn nbn ENSIPUP00000005160 ENSIPUP00000005160 LOC108272432 LOC108272432 LOC108272324 LOC108272324 abraxas1 abraxas1 LOC108269366 LOC108269366 LOC108261983 LOC108261983 cdca7l cdca7l LOC108274842 LOC108274842 rpa1 rpa1 recql4 recql4 mcm5 mcm5 topbp1 topbp1 mcm8 mcm8 psmd5 psmd5 mdc1 mdc1 orc3 orc3 ENSIPUP00000013757 ENSIPUP00000013757 mcm2 mcm2 LOC108261690 LOC108261690 ENSIPUP00000013437 ENSIPUP00000013437 LOC108261379-2 LOC108261379-2 rmi1 rmi1 psmc4 psmc4 ENSIPUP00000012797 ENSIPUP00000012797 LOC108261488 LOC108261488 atm atm LOC108261425 LOC108261425 ENSIPUP00000011897 ENSIPUP00000011897 mcm3 mcm3 psd13 psd13 ENSIPUP00000011577 ENSIPUP00000011577 ENSIPUP00000011444 ENSIPUP00000011444 babam1 babam1 nsd2 nsd2 psma1 psma1 psmb5 psmb5 uimc1 uimc1 rad1 rad1 cdc25b cdc25b LOC108277171 LOC108277171 ENSIPUP00000009144 ENSIPUP00000009144 ywhae ywhae orc1 orc1 kxd1 kxd1 mcm10 mcm10 psma7 psma7 LOC108258228 LOC108258228 LOC100304914 LOC100304914 rps27a rps27a psmb2 psmb2 psmd12 psmd12 atr atr CLSPN CLSPN chek2 chek2 cdk1 cdk1 psme4 psme4 rad9a rad9a psmb1 psmb1 ccnb1 ccnb1 top3a top3a piezo2 piezo2 ube2n ube2n rpa3 rpa3 psmc5 psmc5 LOC108277419 LOC108277419 ankrd12 ankrd12 rhno1 rhno1 dna2 dna2 psmc6 psmc6 exo1 exo1 LOC108255359 LOC108255359 hus1 hus1 psmd11 psmd11 LOC108264466 LOC108264466 rmi2 rmi2 psa6 psa6 psme3 psme3 LOC108267915 LOC108267915 rfc5 rfc5 cdca7 cdca7 LOC108261097 LOC108261097 psmd9 psmd9 rnf169 rnf169 LOC108269934 LOC108269934 rcbtb1 rcbtb1 pkmyt1 pkmyt1 rnf168 rnf168 psmb6 psmb6 mcm9 mcm9 psme2 psme2 rcbtb2 rcbtb2 psmb4 psmb4 tp53 tp53 orc4 orc4 psmb7 psmb7 LOC108258508 LOC108258508 pb9la pb9la wdr41 wdr41 LOC108258501 LOC108258501 PSMB8 PSMB8 orc2 orc2 mcm6 mcm6 rnf8 rnf8 brca1 brca1 psma5 psma5 ENSIPUP00000033019 ENSIPUP00000033019 herc2 herc2 psa2 psa2 ywhah ywhah psma2 psma2 dbf4 dbf4 rad17 rad17 LOC108267136 LOC108267136 tp53bp1 tp53bp1 wee2 wee2 ccnb2 ccnb2 psmd6 psmd6 ywhaq ywhaq ankrd11 ankrd11 piezo1 piezo1 psmc2 psmc2 orc5 orc5 psmd1 psmd1 rfc2 rfc2 LOC108265228 LOC108265228 ENSIPUP00000037149 ENSIPUP00000037149 LOC108271803 LOC108271803 rad9b rad9b cdc45 cdc45 rpa2 rpa2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
slf1SMC5-SMC6 complex localization factor protein 1 isoform X1. (891 aa)
orc6Origin recognition complex subunit 6 isoform X1. (260 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (435 aa)
LOC108258154DNA helicase; Belongs to the MCM family. (791 aa)
LOC10826005614-3-3 protein epsilon-like isoform X1; Belongs to the 14-3-3 family. (254 aa)
psma4Proteasome subunit alpha type. (261 aa)
LOC108262407Histone H2B; Belongs to the histone H2B family. (164 aa)
LOC108262397Histone H4-like. (96 aa)
LOC108255684-5Histone H4. (103 aa)
LOC108255684-4Histone H4. (103 aa)
cdc7Cell division cycle 7-related protein kinase isoform X2. (522 aa)
LOC108270562Wee1-like protein kinase. (532 aa)
ENSIPUP00000019080annotation not available (285 aa)
ENSIPUP00000018991annotation not available (96 aa)
143b114-3-3 protein beta/alpha-1; Belongs to the 14-3-3 family. (244 aa)
LOC108262131Histone H2B-like. (90 aa)
LOC108255684-3Histone H4. (103 aa)
rad50DNA repair protein RAD50 isoform X1. (1311 aa)
psma6Proteasome subunit alpha type. (246 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (301 aa)
ENSIPUP00000018324annotation not available (150 aa)
143g114-3-3 protein gamma-1; Belongs to the 14-3-3 family. (247 aa)
tdrd3Tudor domain-containing protein 3. (801 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (587 aa)
psmd326S proteasome non-ATPase regulatory subunit 3. (514 aa)
LOC108278678G2/mitotic-specific cyclin-B3-like; Belongs to the cyclin family. (414 aa)
LOC108261379-3Histone H2B-like. (124 aa)
LOC108261964Histone H2B; Belongs to the histone H2B family. (124 aa)
LOC108255684-2Histone H4. (103 aa)
ENSIPUP00000017847annotation not available (196 aa)
rfc4Replication factor C subunit 4 isoform X1. (358 aa)
ENSIPUP00000017662annotation not available (150 aa)
LOC108261899Histone H2B-like. (117 aa)
LOC108261901Histone H4-like. (96 aa)
ENSIPUP00000017440annotation not available (144 aa)
LOC108261861Histone H2B; Belongs to the histone H2B family. (125 aa)
LOC108261860Histone H4-like. (96 aa)
ENSIPUP00000017001annotation not available (67 aa)
psmb3Proteasome subunit beta. (205 aa)
LOC108272412Replication protein A 32 kDa subunit-like. (251 aa)
LOC108258592Histone H2A; Belongs to the histone H2A family. (132 aa)
LOC10827093326S proteasome non-ATPase regulatory subunit 13-like isoform X1. (378 aa)
atripATR-interacting protein. (754 aa)
ENSIPUP00000016437annotation not available (175 aa)
ENSIPUP00000016196annotation not available (490 aa)
LOC108271195Wee1-like protein kinase. (285 aa)
LOC108261712Histone H4-like. (81 aa)
LOC10825730214-3-3 protein zeta/delta-like; Belongs to the 14-3-3 family. (243 aa)
brcc3Lys-63-specific deubiquitinase BRCC36 isoform X1. (260 aa)
rfc3Replication factor C subunit 3. (356 aa)
babam2BRCA1-A complex subunit BRE. (386 aa)
psmd426S proteasome non-ATPase regulatory subunit 4. (373 aa)
psmd1426S proteasome non-ATPase regulatory subunit 14. (300 aa)
psmd726S proteasome non-ATPase regulatory subunit 7. (326 aa)
LOC108280894DNA helicase; Belongs to the MCM family. (825 aa)
psme1Proteasome activator complex subunit 1. (246 aa)
mcm4DNA helicase; Belongs to the MCM family. (845 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (148 aa)
LOC108260489Histone H2B; Belongs to the histone H2B family. (117 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (722 aa)
psmd1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
blmBloom syndrome protein isoform X1. (1132 aa)
exd2Exonuclease 3'-5' domain-containing protein 2 isoform X1. (631 aa)
psmd826S proteasome non-ATPase regulatory subunit 8. (267 aa)
psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)
LOC108262486Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
LOC108262497Histone H4-like. (96 aa)
pias4E3 SUMO-protein ligase PIAS4. (506 aa)
LOC108262536Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (100 aa)
rbbp8DNA endonuclease RBBP8. (74 aa)
LOC108261379Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
LOC108262589Histone H4-like. (96 aa)
LOC108255684Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC108262596Histone H4-like. (96 aa)
ENSIPUP00000002007annotation not available (133 aa)
LOC108262617Histone H2B-like. (103 aa)
LOC108262621Histone H4-like. (75 aa)
ENSIPUP00000002141annotation not available (67 aa)
LOC108262673Histone H2B; Belongs to the histone H2B family. (124 aa)
psmf1Proteasome inhibitor PI31 subunit. (270 aa)
LOC10030510514-3-3 protein beta/alpha-A; Belongs to the 14-3-3 family. (232 aa)
chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (466 aa)
psma3Proteasome subunit alpha type. (255 aa)
wrnWerner syndrome ATP-dependent helicase isoform X1. (1429 aa)
ENSIPUP00000002932annotation not available (108 aa)
meiobMeiosis-specific with OB domain-containing protein. (466 aa)
LOC10826544114-3-3 protein beta/alpha-A-like; Belongs to the 14-3-3 family. (245 aa)
psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (427 aa)
nbnNibrin. (831 aa)
ENSIPUP00000005160annotation not available (81 aa)
LOC108272432Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (102 aa)
LOC108272324Histone H2B; Belongs to the histone H2B family. (124 aa)
abraxas1BRCA1-A complex subunit Abraxas. (393 aa)
LOC108269366G2 and S phase-expressed protein 1-like. (777 aa)
LOC108261983Histone H2B-like; Belongs to the histone H2B family. (88 aa)
cdca7lCell division cycle-associated 7-like protein. (473 aa)
LOC108274842Proteasome subunit beta type-7-like. (278 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
recql4ATP-dependent DNA helicase Q4. (1490 aa)
mcm5DNA helicase; Belongs to the MCM family. (736 aa)
topbp1DNA topoisomerase 2-binding protein 1 isoform X7. (1561 aa)
mcm8DNA helicase MCM8; Belongs to the MCM family. (852 aa)
psmd526S proteasome non-ATPase regulatory subunit 5. (505 aa)
mdc1Mediator of DNA damage checkpoint protein 1 isoform X2. (1909 aa)
orc3Origin recognition complex subunit 3 isoform X1. (718 aa)
ENSIPUP00000013757annotation not available (100 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
LOC108261690Histone H4. (96 aa)
ENSIPUP00000013437annotation not available (145 aa)
LOC108261379-2Histone H2B-like. (124 aa)
rmi1recQ-mediated genome instability protein 1. (649 aa)
psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (412 aa)
ENSIPUP00000012797annotation not available (109 aa)
LOC108261488Histone H2B; Belongs to the histone H2B family. (124 aa)
atmNon-specific serine/threonine protein kinase. (3076 aa)
LOC108261425Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
ENSIPUP00000011897annotation not available (218 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
psd1326S proteasome non-ATPase regulatory subunit 13. (400 aa)
ENSIPUP00000011577DNA replication ATP-dependent helicase/nuclease DNA2-like. (96 aa)
ENSIPUP00000011444annotation not available (131 aa)
babam1BRISC and BRCA1-A complex member 1. (369 aa)
nsd2Histone-lysine N-methyltransferase NSD2 isoform X2. (1480 aa)
psma1Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (263 aa)
psmb5Proteasome subunit beta. (277 aa)
uimc1BRCA1-A complex subunit RAP80 isoform X1. (960 aa)
rad1Cell cycle checkpoint protein RAD1 isoform X1. (291 aa)
cdc25bM-phase inducer phosphatase 2. (570 aa)
LOC108277171Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSIPUP00000009144Histone H2B 3. (118 aa)
ywhae14-3-3 protein epsilon isoform X1; Belongs to the 14-3-3 family. (255 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1030 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
mcm10Protein MCM10 homolog isoform X2. (876 aa)
psma7Proteasome subunit alpha type. (251 aa)
LOC108258228Proteasome subunit alpha type-6-like. (228 aa)
LOC100304914Proteasome subunit alpha type. (251 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
psmb2Proteasome subunit beta. (199 aa)
psmd1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
atrSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2616 aa)
CLSPNClaspin. (857 aa)
chek2Serine/threonine-protein kinase Chk2. (539 aa)
cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (302 aa)
psme4Proteasome activator complex subunit 4 isoform X2. (1827 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (384 aa)
psmb1Proteasome subunit beta. (237 aa)
ccnb1G2/mitotic-specific cyclin-B1 isoform X2; Belongs to the cyclin family. (401 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (999 aa)
piezo2Piezo-type mechanosensitive ion channel component. (2893 aa)
ube2nUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
rpa3Replication protein A 14 kDa subunit. (122 aa)
psmc526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
LOC10827741914-3-3 protein gamma-2-like; Belongs to the 14-3-3 family. (247 aa)
ankrd12Ankyrin repeat domain-containing protein 12 isoform X2. (2035 aa)
rhno1RAD9, HUS1, RAD1-interacting nuclear orphan protein 1. (293 aa)
dna2DNA replication ATP-dependent helicase/nuclease DNA2 isoform X4. (1343 aa)
psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (371 aa)
exo1Exonuclease 1 isoform X1. (769 aa)
LOC108255359Uncharacterized protein LOC108255359 isoform X2. (1394 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (281 aa)
psmd1126S proteasome non-ATPase regulatory subunit 11B. (422 aa)
LOC108264466Wee1-like protein kinase. (615 aa)
rmi2RecQ-mediated Genome instability protein 2. (146 aa)
psa6Proteasome subunit alpha type. (246 aa)
psme3Proteasome activator complex subunit 3. (256 aa)
LOC108267915Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (394 aa)
rfc5Replication factor C subunit 5. (339 aa)
cdca7Cell division cycle-associated protein 7. (400 aa)
LOC108261097Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
psmd926S proteasome non-ATPase regulatory subunit 9. (213 aa)
rnf169E3 ubiquitin-protein ligase RNF169. (619 aa)
LOC10826993414-3-3 protein beta/alpha-like; Belongs to the 14-3-3 family. (240 aa)
rcbtb1RCC1 and BTB domain-containing protein 1. (531 aa)
pkmyt1Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase. (528 aa)
rnf168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (461 aa)
psmb6Proteasome subunit beta. (244 aa)
mcm9DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1097 aa)
psme2Proteasome activator complex subunit 2. (242 aa)
rcbtb2RCC1 and BTB domain-containing protein 2. (540 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (215 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (376 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (428 aa)
psmb7Proteasome subunit beta. (318 aa)
LOC108258508Proteasome subunit beta. (218 aa)
pb9laProteasome subunit beta. (214 aa)
wdr41WD repeat-containing protein 41. (451 aa)
LOC108258501Proteasome subunit beta. (274 aa)
PSMB8Proteasome subunit beta. (274 aa)
orc2Origin recognition complex subunit 2. (576 aa)
mcm6DNA helicase; Belongs to the MCM family. (823 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (491 aa)
brca1Breast cancer type 1 susceptibility protein isoform X2. (1369 aa)
psma5Proteasome subunit alpha type. (241 aa)
ENSIPUP00000033019annotation not available (92 aa)
herc2E3 ubiquitin-protein ligase HERC2. (4717 aa)
psa2Proteasome subunit alpha type. (234 aa)
ywhah14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa)
psma2Proteasome 20S subunit alpha 2. (234 aa)
dbf4Protein DBF4 homolog A isoform X2. (634 aa)
rad17Cell cycle checkpoint protein RAD17 isoform X4. (701 aa)
LOC108267136G2/mitotic-specific cyclin-B3-like isoform X1; Belongs to the cyclin family. (432 aa)
tp53bp1Tumor suppressor p53-binding protein 1 isoform X3. (1750 aa)
wee2Wee1-like protein kinase. (546 aa)
ccnb2G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (398 aa)
psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
ywhaq14-3-3 protein theta; Belongs to the 14-3-3 family. (244 aa)
ankrd11Ankyrin repeat domain-containing protein 11 isoform X2. (2820 aa)
piezo1Piezo-type mechanosensitive ion channel component. (2502 aa)
psmc226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
orc5Origin recognition complex subunit 5. (445 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (965 aa)
rfc2Replication factor C subunit 2. (357 aa)
LOC108265228Piezo-type mechanosensitive ion channel component. (543 aa)
ENSIPUP00000037149Piezo-type mechanosensitive ion channel component 2-like. (302 aa)
LOC108271803Piezo-type mechanosensitive ion channel component. (2836 aa)
rad9bCell cycle checkpoint control protein RAD9B isoform X1. (412 aa)
cdc45Cell division control protein 45 homolog. (571 aa)
rpa2Replication protein A 32 kDa subunit. (294 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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