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uba52 uba52 ap2s1 ap2s1 LOC108267679 LOC108267679 ap2a1 ap2a1 kxd1 kxd1 clta clta nr1h3 nr1h3 ap2a2 ap2a2 mylip mylip cltc cltc vldlr vldlr ap2b1 ap2b1 rps27a rps27a clhc1 clhc1 pcsk9 pcsk9 LOC108264350 LOC108264350 LOC108272890 LOC108272890
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (147 aa)
LOC108267679AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
kxd1kxDL motif-containing protein 1 isoform X2. (187 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (234 aa)
nr1h3Oxysterols receptor LXR-alpha isoform X2. (446 aa)
ap2a2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (944 aa)
mylipE3 ubiquitin-protein ligase MYLIP-A. (472 aa)
cltcClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
vldlrVery low-density lipoprotein receptor isoform X1. (876 aa)
ap2b1AP complex subunit beta. (951 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
clhc1Clathrin heavy chain linker domain-containing protein 1 isoform X1. (618 aa)
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (651 aa)
LOC108264350AP-2 complex subunit mu-B. (438 aa)
LOC108272890E3 ubiquitin-protein ligase MYLIP-B-like. (463 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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