17 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	uba52	ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (147 aa)
	LOC108267679	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
	ap2a1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
	kxd1	kxDL motif-containing protein 1 isoform X2. (187 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (234 aa)
	nr1h3	Oxysterols receptor LXR-alpha isoform X2. (446 aa)
	ap2a2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (944 aa)
	mylip	E3 ubiquitin-protein ligase MYLIP-A. (472 aa)
	cltc	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
	vldlr	Very low-density lipoprotein receptor isoform X1. (876 aa)
	ap2b1	AP complex subunit beta. (951 aa)
	rps27a	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
	clhc1	Clathrin heavy chain linker domain-containing protein 1 isoform X1. (618 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (651 aa)
	LOC108264350	AP-2 complex subunit mu-B. (438 aa)
	LOC108272890	E3 ubiquitin-protein ligase MYLIP-B-like. (463 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108264350	ap2a1	ENSIPUP00000020061	ENSIPUP00000009719	AP-2 complex subunit mu-B.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.944
LOC108264350	ap2a2	ENSIPUP00000020061	ENSIPUP00000026518	AP-2 complex subunit mu-B.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.944
LOC108264350	ap2b1	ENSIPUP00000020061	ENSIPUP00000035796	AP-2 complex subunit mu-B.	AP complex subunit beta.	0.955
LOC108264350	ap2s1	ENSIPUP00000020061	ENSIPUP00000034411	AP-2 complex subunit mu-B.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.985
LOC108264350	clhc1	ENSIPUP00000020061	ENSIPUP00000022517	AP-2 complex subunit mu-B.	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	0.770
LOC108264350	clta	ENSIPUP00000020061	ENSIPUP00000033043	AP-2 complex subunit mu-B.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.833
LOC108264350	cltc	ENSIPUP00000020061	ENSIPUP00000023082	AP-2 complex subunit mu-B.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.898
LOC108264350	rps27a	ENSIPUP00000020061	ENSIPUP00000022626	AP-2 complex subunit mu-B.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.641
LOC108264350	uba52	ENSIPUP00000020061	ENSIPUP00000007381	AP-2 complex subunit mu-B.	ubiquitin-60S ribosomal protein L40 isoform X1.	0.629
LOC108264350	vldlr	ENSIPUP00000020061	ENSIPUP00000037055	AP-2 complex subunit mu-B.	Very low-density lipoprotein receptor isoform X1.	0.419
LOC108267679	ap2a1	ENSIPUP00000018897	ENSIPUP00000009719	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.991
LOC108267679	ap2a2	ENSIPUP00000018897	ENSIPUP00000026518	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.991
LOC108267679	ap2b1	ENSIPUP00000018897	ENSIPUP00000035796	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta.	0.993
LOC108267679	ap2s1	ENSIPUP00000018897	ENSIPUP00000034411	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.997
LOC108267679	clhc1	ENSIPUP00000018897	ENSIPUP00000022517	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	0.770
LOC108267679	clta	ENSIPUP00000018897	ENSIPUP00000033043	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.833
LOC108267679	cltc	ENSIPUP00000018897	ENSIPUP00000023082	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.968
LOC108267679	rps27a	ENSIPUP00000018897	ENSIPUP00000022626	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.641
LOC108267679	uba52	ENSIPUP00000018897	ENSIPUP00000007381	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	ubiquitin-60S ribosomal protein L40 isoform X1.	0.629
LOC108267679	vldlr	ENSIPUP00000018897	ENSIPUP00000037055	AP-2 complex subunit mu-A-like isoform X1; Belongs to the adaptor complexes medium subunit family.	Very low-density lipoprotein receptor isoform X1.	0.419