8 items (Ictalurus punctatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

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Your Input:
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	kxd1	kxDL motif-containing protein 1 isoform X2. (187 aa)
	usp7	Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family. (1112 aa)
	rps27a	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
	nedd4	E3 ubiquitin-protein ligase NEDD4. (900 aa)
	LOC108269686	annotation not available (442 aa)
	xiap	E3 ubiquitin-protein ligase XIAP isoform X2. (437 aa)
	LOC108269206	E3 ubiquitin-protein ligase XIAP-like isoform X1. (386 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108269206	LOC108269686	ENSIPUP00000000677	ENSIPUP00000026656	E3 ubiquitin-protein ligase XIAP-like isoform X1.	annotation not available	0.548
LOC108269206	pten	ENSIPUP00000000677	ENSIPUP00000004920	E3 ubiquitin-protein ligase XIAP-like isoform X1.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.548
LOC108269206	rps27a	ENSIPUP00000000677	ENSIPUP00000022626	E3 ubiquitin-protein ligase XIAP-like isoform X1.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.797
LOC108269206	xiap	ENSIPUP00000000677	ENSIPUP00000000674	E3 ubiquitin-protein ligase XIAP-like isoform X1.	E3 ubiquitin-protein ligase XIAP isoform X2.	0.900
LOC108269686	LOC108269206	ENSIPUP00000026656	ENSIPUP00000000677	annotation not available	E3 ubiquitin-protein ligase XIAP-like isoform X1.	0.548
LOC108269686	nedd4	ENSIPUP00000026656	ENSIPUP00000023237	annotation not available	E3 ubiquitin-protein ligase NEDD4.	0.634
LOC108269686	pten	ENSIPUP00000026656	ENSIPUP00000004920	annotation not available	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.901
LOC108269686	rps27a	ENSIPUP00000026656	ENSIPUP00000022626	annotation not available	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.583
LOC108269686	usp7	ENSIPUP00000026656	ENSIPUP00000021605	annotation not available	Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family.	0.813
LOC108269686	xiap	ENSIPUP00000026656	ENSIPUP00000000674	annotation not available	E3 ubiquitin-protein ligase XIAP isoform X2.	0.548
kxd1	rps27a	ENSIPUP00000008247	ENSIPUP00000022626	kxDL motif-containing protein 1 isoform X2.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.802
nedd4	LOC108269686	ENSIPUP00000023237	ENSIPUP00000026656	E3 ubiquitin-protein ligase NEDD4.	annotation not available	0.634
nedd4	pten	ENSIPUP00000023237	ENSIPUP00000004920	E3 ubiquitin-protein ligase NEDD4.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.634
nedd4	rps27a	ENSIPUP00000023237	ENSIPUP00000022626	E3 ubiquitin-protein ligase NEDD4.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.841
pten	LOC108269206	ENSIPUP00000004920	ENSIPUP00000000677	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	E3 ubiquitin-protein ligase XIAP-like isoform X1.	0.548
pten	LOC108269686	ENSIPUP00000004920	ENSIPUP00000026656	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	annotation not available	0.901
pten	nedd4	ENSIPUP00000004920	ENSIPUP00000023237	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	E3 ubiquitin-protein ligase NEDD4.	0.634
pten	rps27a	ENSIPUP00000004920	ENSIPUP00000022626	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.583
pten	usp7	ENSIPUP00000004920	ENSIPUP00000021605	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family.	0.813
pten	xiap	ENSIPUP00000004920	ENSIPUP00000000674	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	E3 ubiquitin-protein ligase XIAP isoform X2.	0.548