STRINGSTRING
LOC108255503 LOC108255503 pik3ca pik3ca LOC108275608 LOC108275608 crkl crkl yes1 yes1 pik3cd pik3cd uba52 uba52 LOC108270342 LOC108270342 crk crk pik3r3 pik3r3 rapgef1 rapgef1 LOC108256494 LOC108256494 pik3cb pik3cb LOC108265900 LOC108265900 hck hck cbl cbl LOC108269225 LOC108269225 CRK CRK rps27a rps27a LOC108258139 LOC108258139 pik3r1 pik3r1 grb2 grb2 syk syk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108255503Tyrosine-protein kinase. (532 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
LOC108275608Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
crklCrk-like protein. (305 aa)
yes1Tyrosine-protein kinase. (547 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
uba52ubiquitin-60S ribosomal protein L40 isoform X1. (128 aa)
LOC108270342Tyrosine-protein kinase. (538 aa)
crkAdapter molecule crk. (308 aa)
pik3r3Phosphatidylinositol 3-kinase regulatory subunit alpha. (739 aa)
rapgef1Rap guanine nucleotide exchange factor 1 isoform X4. (1101 aa)
LOC108256494Growth factor receptor-bound protein 2. (217 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
LOC108265900Rap guanine nucleotide exchange factor 1-like isoform X1. (1061 aa)
hckTyrosine-protein kinase. (503 aa)
cblE3 ubiquitin-protein ligase CBL. (911 aa)
LOC108269225E3 ubiquitin-protein ligase CBL-like isoform X1. (625 aa)
CRKAdapter molecule crk-like. (357 aa)
rps27aUbiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)
LOC108258139Tyrosine-protein kinase. (490 aa)
pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (728 aa)
grb2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
sykTyrosine-protein kinase. (627 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (22%) [HD]