13 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108269786	E3 ubiquitin-protein ligase pellino homolog 1-like. (424 aa)
	LOC108258444	E3 ubiquitin-protein ligase pellino homolog 1-like isoform X1. (468 aa)
	LOC108255212	Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
	ikbkb	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (776 aa)
	LOC108270353	E3 ubiquitin-protein ligase pellino homolog 2-like. (442 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	chuk	Inhibitor of Nuclear factor kappa-B kinase subunit alpha. (756 aa)
	LOC108258111	E3 ubiquitin-protein ligase pellino homolog 2-like. (426 aa)
	LOC108267165	E3 ubiquitin-protein ligase pellino homolog 1-like isoform X1. (492 aa)
	ube2n	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	irak1	Interleukin-1 receptor-associated kinase 1 isoform X4. (718 aa)
	ikbkg	NF-kappa-B essential modulator. (568 aa)
	rps27a	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108255212	LOC108258111	ENSIPUP00000003446	ENSIPUP00000030084	Ubiquitin-conjugating enzyme E2 variant 1.	E3 ubiquitin-protein ligase pellino homolog 2-like.	0.726
LOC108255212	LOC108258444	ENSIPUP00000003446	ENSIPUP00000012557	Ubiquitin-conjugating enzyme E2 variant 1.	E3 ubiquitin-protein ligase pellino homolog 1-like isoform X1.	0.726
LOC108255212	LOC108267165	ENSIPUP00000003446	ENSIPUP00000026396	Ubiquitin-conjugating enzyme E2 variant 1.	E3 ubiquitin-protein ligase pellino homolog 1-like isoform X1.	0.726
LOC108255212	LOC108269786	ENSIPUP00000003446	ENSIPUP00000019757	Ubiquitin-conjugating enzyme E2 variant 1.	E3 ubiquitin-protein ligase pellino homolog 1-like.	0.726
LOC108255212	LOC108270353	ENSIPUP00000003446	ENSIPUP00000035758	Ubiquitin-conjugating enzyme E2 variant 1.	E3 ubiquitin-protein ligase pellino homolog 2-like.	0.726
LOC108255212	chuk	ENSIPUP00000003446	ENSIPUP00000031478	Ubiquitin-conjugating enzyme E2 variant 1.	Inhibitor of Nuclear factor kappa-B kinase subunit alpha.	0.692
LOC108255212	ikbkb	ENSIPUP00000003446	ENSIPUP00000037211	Ubiquitin-conjugating enzyme E2 variant 1.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	0.692
LOC108255212	ikbkg	ENSIPUP00000003446	ENSIPUP00000019557	Ubiquitin-conjugating enzyme E2 variant 1.	NF-kappa-B essential modulator.	0.686
LOC108255212	irak1	ENSIPUP00000003446	ENSIPUP00000019227	Ubiquitin-conjugating enzyme E2 variant 1.	Interleukin-1 receptor-associated kinase 1 isoform X4.	0.536
LOC108255212	rps27a	ENSIPUP00000003446	ENSIPUP00000022626	Ubiquitin-conjugating enzyme E2 variant 1.	Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]	0.999
LOC108255212	traf6	ENSIPUP00000003446	ENSIPUP00000032978	Ubiquitin-conjugating enzyme E2 variant 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.731
LOC108255212	ube2n	ENSIPUP00000003446	ENSIPUP00000025480	Ubiquitin-conjugating enzyme E2 variant 1.	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.	0.976
LOC108258111	LOC108255212	ENSIPUP00000030084	ENSIPUP00000003446	E3 ubiquitin-protein ligase pellino homolog 2-like.	Ubiquitin-conjugating enzyme E2 variant 1.	0.726
LOC108258111	chuk	ENSIPUP00000030084	ENSIPUP00000031478	E3 ubiquitin-protein ligase pellino homolog 2-like.	Inhibitor of Nuclear factor kappa-B kinase subunit alpha.	0.474
LOC108258111	ikbkb	ENSIPUP00000030084	ENSIPUP00000037211	E3 ubiquitin-protein ligase pellino homolog 2-like.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	0.552
LOC108258111	irak1	ENSIPUP00000030084	ENSIPUP00000019227	E3 ubiquitin-protein ligase pellino homolog 2-like.	Interleukin-1 receptor-associated kinase 1 isoform X4.	0.813
LOC108258111	traf6	ENSIPUP00000030084	ENSIPUP00000032978	E3 ubiquitin-protein ligase pellino homolog 2-like.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.727
LOC108258111	ube2n	ENSIPUP00000030084	ENSIPUP00000025480	E3 ubiquitin-protein ligase pellino homolog 2-like.	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.	0.642
LOC108258444	LOC108255212	ENSIPUP00000012557	ENSIPUP00000003446	E3 ubiquitin-protein ligase pellino homolog 1-like isoform X1.	Ubiquitin-conjugating enzyme E2 variant 1.	0.726
LOC108258444	chuk	ENSIPUP00000012557	ENSIPUP00000031478	E3 ubiquitin-protein ligase pellino homolog 1-like isoform X1.	Inhibitor of Nuclear factor kappa-B kinase subunit alpha.	0.474